SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e7o'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 5e7o DMSO REDUCTASE
FAMILY TYPE II
ENZYME, IRON-SULFUR
SUBUNIT
(Azospira
oryzae) 		3 / 3 THR B 141
PRO B 254
THR B 252
 None
None
SF4  B 403 ( 4.9A)
 0.96A 1dscC-5e7oB:
undetectable		 1dscC-5e7oB:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 5e7o DMSO REDUCTASE
FAMILY TYPE II
ENZYME, IRON-SULFUR
SUBUNIT
(Azospira
oryzae) 		3 / 3 THR B 252
THR B 141
PRO B 254
 SF4  B 403 ( 4.9A)
None
None
 0.83A 1fjaC-5e7oB:
undetectable		 1fjaC-5e7oB:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 5e7o DMSO REDUCTASE
FAMILY TYPE II
ENZYME, IRON-SULFUR
SUBUNIT
(Azospira
oryzae) 		3 / 3 THR B 252
THR B 141
PRO B 254
 SF4  B 403 ( 4.9A)
None
None
 0.83A 1fjaD-5e7oB:
undetectable		 1fjaD-5e7oB:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 5e7o DMSO REDUCTASE
FAMILY TYPE II
ENZYME, IRON-SULFUR
SUBUNIT
(Azospira
oryzae) 		3 / 3 THR B 141
THR B 252
PRO B 143
 None
SF4  B 403 ( 4.9A)
SF4  B 403 ( 4.8A)
 0.84A 1qfiB-5e7oB:
undetectable		 1qfiB-5e7oB:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5e7o DMSO REDUCTASE
FAMILY TYPE II
ENZYME, IRON-SULFUR
SUBUNIT
(Azospira
oryzae) 		4 / 5 PRO B 281
GLY B 123
ASN B 128
GLY B 121
 None
 1.14A 1zlqA-5e7oB:
undetectable		 1zlqA-5e7oB:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 5e7o DMSO REDUCTASE
FAMILY TYPE II
ENZYME, IRON-SULFUR
SUBUNIT
(Azospira
oryzae) 		3 / 3 THR B 252
THR B 141
PRO B 254
 SF4  B 403 ( 4.9A)
None
None
 0.81A 209dC-5e7oB:
undetectable		 209dC-5e7oB:
4.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGK_A_0TXA302_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5e7o DMSO REDUCTASE
FAMILY TYPE II
ENZYME, IRON-SULFUR
SUBUNIT
(Azospira
oryzae) 		4 / 6 GLN B 174
PHE B 187
ILE B  78
PRO B  79
 None
 1.12A 4fgkA-5e7oB:
undetectable		 4fgkA-5e7oB:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JS5_A_ASCA202_0
(CYTOCHROME C')		 5e7o DMSO REDUCTASE
FAMILY TYPE II
ENZYME, IRON-SULFUR
SUBUNIT
(Azospira
oryzae) 		3 / 3 CYH B 170
LYS B 169
HIS B 166
 F3S  B 402 (-2.8A)
None
None
 1.28A 5js5A-5e7oB:
undetectable		 5js5A-5e7oB:
15.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XOO_A_ADNA506_1
(GLYCOSAMINOGLYCAN
XYLOSYLKINASE)		 5e7o DMSO REDUCTASE
FAMILY TYPE II
ENZYME, IRON-SULFUR
SUBUNIT
(Azospira
oryzae) 		4 / 6 TYR B 182
LEU B 288
GLU B  50
LEU B 133
 None
 1.45A 5xooA-5e7oB:
undetectable		 5xooA-5e7oB:
14.56