SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e7p'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZ4_B_CAMB502_0
(CYTOCHROME P450-CAM)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 404
VAL A 427
VAL A 233
ASP A 230
 ADP  A 901 (-4.9A)
ADP  A 901 ( 4.4A)
None
None
 1.17A 1dz4B-5e7pA:
undetectable		 1dz4B-5e7pA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DZM_A_BZMA600_0
(ODORANT-BINDING
PROTEIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 8 ILE A 670
VAL A 726
GLY A 667
LEU A 678
 None
 0.94A 1dzmA-5e7pA:
undetectable		 1dzmA-5e7pA:
10.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 9 LEU A 352
ILE A 348
VAL A 297
GLY A 298
LEU A 292
 None
 1.25A 1e7aB-5e7pA:
undetectable		 1e7aB-5e7pA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FK6_A_LNLA1201_1
(NON-SPECIFIC LIPID
TRANSFER PROTEIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 678
ALA A 682
ARG A 659
LEU A 697
ALA A  48
 None
 1.00A 1fk6A-5e7pA:
undetectable		 1fk6A-5e7pA:
7.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_B_ESTB1600_1
(ESTROGEN RECEPTOR)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 645
LEU A 611
LEU A 610
ILE A 617
GLY A 616
 None
 1.17A 1g50B-5e7pA:
undetectable		 1g50B-5e7pA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1G50_C_ESTC2600_1
(ESTROGEN RECEPTOR)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 11 LEU A 645
LEU A 611
LEU A 610
ILE A 617
GLY A 616
 None
 1.17A 1g50C-5e7pA:
undetectable		 1g50C-5e7pA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 5 GLY A 321
GLN A 220
VAL A 217
SER A 319
 None
 1.28A 1p6kB-5e7pA:
undetectable		 1p6kB-5e7pA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_J_CHDJ3060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 1.00A 1v54A-5e7pA:
undetectable
1v54J-5e7pA:
undetectable		 1v54A-5e7pA:
22.32
1v54J-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZU_B_ACTB861_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 5 GLY A 321
GLN A 220
VAL A 217
SER A 319
 None
 1.23A 1zzuB-5e7pA:
undetectable		 1zzuB-5e7pA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		3 / 3 ASP A 486
PHE A 534
ARG A  53
 None
ADP  A 902 (-3.8A)
None
 0.89A 2a3aA-5e7pA:
undetectable		 2a3aA-5e7pA:
18.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_A_1FLA2002_1
(SERUM ALBUMIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 10 LEU A 639
LEU A 610
ALA A 591
LEU A 570
VAL A 567
 None
 1.10A 2bxeA-5e7pA:
2.4		 2bxeA-5e7pA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXE_B_1FLB2001_1
(SERUM ALBUMIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 352
ILE A 348
VAL A 297
GLY A 298
LEU A 292
 None
 1.29A 2bxeB-5e7pA:
undetectable		 2bxeB-5e7pA:
21.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CIZ_A_ACTA1320_0
(CHLOROPEROXIDASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 ALA A 277
PHE A 324
ILE A 364
VAL A 268
 ADP  A 901 (-3.4A)
None
None
None
 0.84A 2cizA-5e7pA:
undetectable		 2cizA-5e7pA:
17.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 1.02A 2dyrA-5e7pA:
undetectable
2dyrJ-5e7pA:
undetectable		 2dyrA-5e7pA:
22.32
2dyrJ-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_J_CHDJ101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 1.04A 2dysA-5e7pA:
undetectable
2dysJ-5e7pA:
undetectable		 2dysA-5e7pA:
22.32
2dysJ-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_W_CHDW101_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 1.00A 2dysN-5e7pA:
undetectable
2dysW-5e7pA:
undetectable		 2dysN-5e7pA:
22.32
2dysW-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 0.99A 2eijA-5e7pA:
undetectable
2eijJ-5e7pA:
undetectable		 2eijA-5e7pA:
22.32
2eijJ-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 7 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 0.97A 2eikA-5e7pA:
undetectable
2eikJ-5e7pA:
undetectable		 2eikA-5e7pA:
22.32
2eikJ-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 0.97A 2eilA-5e7pA:
undetectable
2eilJ-5e7pA:
undetectable		 2eilA-5e7pA:
22.32
2eilJ-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_2_BO221405_1
(PROTEASOME COMPONENT
PRE3)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 11 THR A 188
THR A  66
THR A  65
ALA A  92
ALA A  68
 None
 1.02A 2f162-5e7pA:
undetectable		 2f162-5e7pA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F16_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 11 THR A 188
THR A  66
THR A  65
ALA A  92
ALA A  68
 None
 1.02A 2f16N-5e7pA:
undetectable		 2f16N-5e7pA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J7X_A_ESTA1454_1
(ESTROGEN RECEPTOR
BETA)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A  24
LEU A  60
LEU A 101
GLY A  93
LEU A  89
 None
 1.14A 2j7xA-5e7pA:
undetectable		 2j7xA-5e7pA:
15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_A_ACTA1121_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 5 SER A 112
VAL A 183
SER A 198
VAL A 196
 None
 1.35A 2j9cA-5e7pA:
undetectable
2j9cB-5e7pA:
undetectable
2j9cC-5e7pA:
undetectable		 2j9cA-5e7pA:
9.77
2j9cB-5e7pA:
9.77
2j9cC-5e7pA:
9.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NV4_B_SAMB202_0
(UPF0066 PROTEIN
AF_0241)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ALA A 428
PRO A 271
GLY A 480
LEU A 469
SER A 472
 ADP  A 901 ( 3.7A)
PG4  A 903 (-3.8A)
None
None
None
 1.38A 2nv4B-5e7pA:
undetectable		 2nv4B-5e7pA:
11.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 4 ALA A 690
VAL A 694
PHE A 534
THR A 665
 ADP  A 902 (-3.3A)
None
ADP  A 902 (-3.8A)
None
 1.41A 2pkkA-5e7pA:
undetectable		 2pkkA-5e7pA:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RHM_B_BEZB194_0
(PUTATIVE KINASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 5 PRO A 632
ILE A 635
ARG A 593
ASP A 588
 None
 1.45A 2rhmB-5e7pA:
2.8		 2rhmB-5e7pA:
13.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZAW_A_CAMA422_0
(CYTOCHROME P450-CAM)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 404
VAL A 427
VAL A 233
ASP A 230
 ADP  A 901 (-4.9A)
ADP  A 901 ( 4.4A)
None
None
 1.20A 2zawA-5e7pA:
undetectable		 2zawA-5e7pA:
21.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 1.08A 2zxwA-5e7pA:
undetectable
2zxwJ-5e7pA:
undetectable		 2zxwA-5e7pA:
22.32
2zxwJ-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A51_C_VDYC6178_1
(VITAMIN D
HYDROXYLASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 325
LEU A 323
ILE A 348
VAL A 373
LEU A 377
 None
 1.20A 3a51C-5e7pA:
undetectable		 3a51C-5e7pA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 8 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 0.93A 3ablN-5e7pA:
undetectable
3ablW-5e7pA:
undetectable		 3ablN-5e7pA:
22.32
3ablW-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_J_CHDJ60_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 1.01A 3abmA-5e7pA:
undetectable
3abmJ-5e7pA:
undetectable		 3abmA-5e7pA:
22.32
3abmJ-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		3 / 3 PRO A  44
LEU A  47
ARG A  53
 None
 0.82A 3aqiB-5e7pA:
undetectable		 3aqiB-5e7pA:
18.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 1.00A 3asnA-5e7pA:
undetectable
3asnJ-5e7pA:
undetectable		 3asnA-5e7pA:
22.32
3asnJ-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_J_CHDJ60_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 1.01A 3asoA-5e7pA:
undetectable
3asoJ-5e7pA:
undetectable		 3asoA-5e7pA:
22.32
3asoJ-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 5 VAL A  40
VAL A  39
THR A  66
ARG A  41
 None
 1.20A 3bjwA-5e7pA:
undetectable		 3bjwA-5e7pA:
8.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 8 SER A 472
SER A 190
GLY A 136
PRO A 193
 None
None
None
ADP  A 901 (-4.5A)
 0.94A 3lslA-5e7pA:
undetectable
3lslD-5e7pA:
undetectable		 3lslA-5e7pA:
15.07
3lslD-5e7pA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_2_BO221405_1
(PROTEASOME COMPONENT
PRE3
PROTEASOME COMPONENT
PUP1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A 188
THR A  66
THR A  65
ALA A  92
ALA A  68
 None
 1.02A 3mg02-5e7pA:
undetectable
3mg0V-5e7pA:
undetectable		 3mg02-5e7pA:
13.26
3mg0V-5e7pA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MG0_N_BO2N1404_1
(PROTEASOME COMPONENT
PRE3)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 11 THR A 188
THR A  66
THR A  65
ALA A  92
ALA A  68
 None
 1.01A 3mg0N-5e7pA:
undetectable		 3mg0N-5e7pA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGP_B_017B200_1
(FIV PROTEASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 10 LEU A 614
ALA A 591
MET A 556
GLY A 552
LEU A 610
 None
 1.01A 3ogpA-5e7pA:
undetectable		 3ogpA-5e7pA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OGQ_A_AB1A200_1
(FIV PROTEASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		6 / 10 LEU A 614
ALA A 591
VAL A 606
MET A 556
GLY A 552
LEU A 610
 None
 1.06A 3ogqA-5e7pA:
undetectable		 3ogqA-5e7pA:
8.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OLS_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A  24
LEU A  60
LEU A 101
GLY A  93
LEU A  89
 None
 1.09A 3olsA-5e7pA:
undetectable		 3olsA-5e7pA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RF4_B_FUNB202_1
(MACROPHAGE MIGRATION
INHIBITORY FACTOR)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 11 ILE A 364
ARG A 281
VAL A 322
PHE A 324
VAL A 289
 None
 1.29A 3rf4A-5e7pA:
undetectable
3rf4B-5e7pA:
undetectable		 3rf4A-5e7pA:
10.75
3rf4B-5e7pA:
10.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E3H_A_HQEA303_1
(CARBONIC ANHYDRASE 2)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 10 VAL A 115
LEU A 178
VAL A 180
LEU A 134
VAL A 145
 None
 1.00A 4e3hA-5e7pA:
undetectable		 4e3hA-5e7pA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_A_SUZA201_1
(TRANSTHYRETIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 7 ALA A 182
SER A 112
THR A 114
SER A 198
 None
 0.69A 4iklA-5e7pA:
undetectable
4iklB-5e7pA:
undetectable		 4iklA-5e7pA:
10.47
4iklB-5e7pA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IKL_B_SUZB201_1
(TRANSTHYRETIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 8 SER A 198
ALA A 182
SER A 112
THR A 114
 None
 0.70A 4iklA-5e7pA:
undetectable
4iklB-5e7pA:
undetectable		 4iklA-5e7pA:
10.47
4iklB-5e7pA:
10.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J26_A_ESTA600_1
(ESTROGEN RECEPTOR
BETA)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A  24
LEU A  60
LEU A 101
GLY A  93
LEU A  89
 None
 1.09A 4j26A-5e7pA:
undetectable		 4j26A-5e7pA:
14.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OQR_A_2UOA502_1
(CYP105AS1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 9 VAL A  94
ALA A  92
THR A  88
VAL A  40
ALA A  82
 None
 1.25A 4oqrA-5e7pA:
undetectable		 4oqrA-5e7pA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_B_BO2B201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A 188
THR A  66
THR A  65
ALA A  92
ALA A  68
 None
 1.02A 4qvnV-5e7pA:
undetectable
4qvnb-5e7pA:
undetectable		 4qvnV-5e7pA:
15.84
4qvnb-5e7pA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVN_N_BO2N201_1
(PROTEASOME SUBUNIT
BETA TYPE-2
PROTEASOME SUBUNIT
BETA TYPE-1)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A 188
THR A  66
THR A  65
ALA A  92
ALA A  68
 None
 1.02A 4qvnH-5e7pA:
undetectable
4qvnN-5e7pA:
undetectable		 4qvnH-5e7pA:
15.84
4qvnN-5e7pA:
13.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4X20_D_LOCD502_2
(TUBULIN BETA CHAIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 11 LEU A 454
LEU A 439
ALA A 166
VAL A 169
ILE A 171
 None
 1.16A 4x20D-5e7pA:
undetectable		 4x20D-5e7pA:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_A_HISA302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A  62
VAL A  94
THR A  66
VAL A 100
LEU A  84
 None
 1.27A 4yb6A-5e7pA:
undetectable
4yb6E-5e7pA:
undetectable		 4yb6A-5e7pA:
17.96
4yb6E-5e7pA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_B_HISB302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A  62
VAL A  94
THR A  66
VAL A 100
LEU A  84
 None
 1.27A 4yb6B-5e7pA:
undetectable
4yb6C-5e7pA:
undetectable		 4yb6B-5e7pA:
17.96
4yb6C-5e7pA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_C_HISC302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 10 GLY A  62
VAL A  94
THR A  66
VAL A 100
LEU A  84
 None
 1.20A 4yb6C-5e7pA:
undetectable
4yb6F-5e7pA:
undetectable		 4yb6C-5e7pA:
17.96
4yb6F-5e7pA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_D_HISD302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 10 LEU A  84
GLY A  62
VAL A  94
THR A  66
VAL A 100
 None
 1.17A 4yb6A-5e7pA:
undetectable
4yb6D-5e7pA:
undetectable		 4yb6A-5e7pA:
17.96
4yb6D-5e7pA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_E_HISE302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 10 LEU A  84
GLY A  62
VAL A  94
THR A  66
VAL A 100
 None
 1.22A 4yb6D-5e7pA:
undetectable
4yb6E-5e7pA:
undetectable		 4yb6D-5e7pA:
17.96
4yb6E-5e7pA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YB6_F_HISF302_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 10 LEU A  84
GLY A  62
VAL A  94
THR A  66
VAL A 100
 None
 1.29A 4yb6B-5e7pA:
undetectable
4yb6F-5e7pA:
undetectable		 4yb6B-5e7pA:
17.96
4yb6F-5e7pA:
17.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_C_ACTC1740_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGS
FAD-BINDING SUBUNIT)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 4 VAL A 297
GLU A 296
GLY A 294
LEU A 292
 None
 1.11A 5g5gC-5e7pA:
undetectable		 5g5gC-5e7pA:
26.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GTR_A_ESTA601_1
(ESTROGEN RECEPTOR)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A  24
LEU A  60
LEU A 101
GLY A  93
LEU A  89
 None
 1.15A 5gtrA-5e7pA:
undetectable		 5gtrA-5e7pA:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_B_6V8B304_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A 188
THR A  66
THR A  65
ALA A  92
ALA A  68
 None
 1.10A 5lf7V-5e7pA:
undetectable
5lf7b-5e7pA:
undetectable		 5lf7V-5e7pA:
15.71
5lf7b-5e7pA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_N_6V8N305_0
(PROTEASOME SUBUNIT
BETA TYPE-6
PROTEASOME SUBUNIT
BETA TYPE-7)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A 188
THR A  66
THR A  65
ALA A  92
ALA A  68
 None
 1.08A 5lf7H-5e7pA:
undetectable
5lf7N-5e7pA:
undetectable		 5lf7H-5e7pA:
15.71
5lf7N-5e7pA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MFX_A_ACTA701_0
(GENOME POLYPROTEIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 5 ARG A 397
THR A 395
ALA A 396
ASP A 393
 None
 1.36A 5mfxA-5e7pA:
4.6		 5mfxA-5e7pA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 587
GLY A 627
VAL A 625
PHE A 571
ALA A 591
 None
 1.02A 5n0oA-5e7pA:
3.5		 5n0oA-5e7pA:
21.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0R_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 587
GLY A 627
VAL A 625
PHE A 571
ALA A 591
 None
 1.03A 5n0rA-5e7pA:
undetectable		 5n0rA-5e7pA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0S_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 587
GLY A 627
VAL A 625
PHE A 571
ALA A 591
 None
 1.03A 5n0sA-5e7pA:
undetectable		 5n0sA-5e7pA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 587
GLY A 627
VAL A 625
PHE A 571
ALA A 591
 None
 1.04A 5n0tA-5e7pA:
3.6		 5n0tA-5e7pA:
21.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 587
GLY A 627
VAL A 625
PHE A 571
ALA A 591
 None
 1.02A 5n0wA-5e7pA:
undetectable		 5n0wA-5e7pA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0W_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 587
GLY A 627
VAL A 625
PHE A 571
ALA A 591
 None
 1.00A 5n0wB-5e7pA:
3.5		 5n0wB-5e7pA:
21.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N4I_A_SAMA501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ILE A 587
GLY A 627
VAL A 625
PHE A 571
ALA A 591
 None
 1.03A 5n4iA-5e7pA:
undetectable		 5n4iA-5e7pA:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 9 ARG A 706
LEU A  47
ILE A  52
GLY A  51
LEU A  42
 None
 0.92A 5o96A-5e7pA:
undetectable
5o96B-5e7pA:
undetectable		 5o96A-5e7pA:
16.37
5o96B-5e7pA:
16.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VC0_A_RITA602_1
(CYTOCHROME P450 3A4)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 ASP A 293
ARG A 131
LEU A 430
ILE A 466
ILE A 171
 None
 1.16A 5vc0A-5e7pA:
undetectable		 5vc0A-5e7pA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 6 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 0.98A 5x1fA-5e7pA:
2.2
5x1fJ-5e7pA:
undetectable		 5x1fA-5e7pA:
22.32
5x1fJ-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 8 LEU A 430
ARG A  37
THR A 464
LEU A 463
 None
 0.92A 5xdxN-5e7pA:
undetectable
5xdxW-5e7pA:
undetectable		 5xdxN-5e7pA:
22.32
5xdxW-5e7pA:
4.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_A_ECLA1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 7 ILE A 587
LEU A 590
ILE A 617
ALA A 566
 None
 0.84A 6b5vA-5e7pA:
undetectable
6b5vC-5e7pA:
undetectable		 6b5vA-5e7pA:
6.71
6b5vC-5e7pA:
6.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_C_ECLC1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 7 ILE A 587
LEU A 590
ILE A 617
ALA A 566
 None
 0.84A 6b5vC-5e7pA:
undetectable
6b5vD-5e7pA:
undetectable		 6b5vC-5e7pA:
6.71
6b5vD-5e7pA:
6.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5V_D_ECLD1001_1
(TRANSIENT RECEPTOR
POTENTIAL CATION
CHANNEL SUBFAMILY V
MEMBER 5)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 7 ALA A 566
ILE A 587
LEU A 590
ILE A 617
 None
 0.84A 6b5vB-5e7pA:
undetectable
6b5vD-5e7pA:
undetectable		 6b5vB-5e7pA:
6.71
6b5vD-5e7pA:
6.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSG_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 10 LEU A 640
VAL A 522
TYR A 525
GLY A 627
LEU A 648
 None
 1.47A 6bsgA-5e7pA:
2.8		 6bsgA-5e7pA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BSI_A_EFZA601_1
(REVERSE
TRANSCRIPTASE P66
SUBUNIT)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 10 LEU A 640
VAL A 522
TYR A 525
GLY A 627
LEU A 648
 None
 1.36A 6bsiA-5e7pA:
undetectable		 6bsiA-5e7pA:
7.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXM_A_SAMA402_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 LEU A 640
LEU A 570
ARG A 644
ILE A 617
ASP A 615
 None
 1.09A 6bxmA-5e7pA:
2.4		 6bxmA-5e7pA:
17.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_2
(TUBULIN BETA CHAIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 5 LEU A 377
THR A 366
ARG A 305
ARG A 111
 None
 1.25A 6ew0B-5e7pA:
undetectable		 6ew0B-5e7pA:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_2
(TUBULIN BETA CHAIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 5 LEU A 377
THR A 366
ARG A 305
ARG A 111
 None
 1.25A 6ew0D-5e7pA:
undetectable		 6ew0D-5e7pA:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_2
(TUBULIN BETA CHAIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 5 LEU A 377
THR A 366
ARG A 305
ARG A 111
 None
 1.26A 6ew0H-5e7pA:
undetectable		 6ew0H-5e7pA:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_2
(TUBULIN BETA CHAIN)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		4 / 5 LEU A 377
THR A 366
ARG A 305
ARG A 111
 None
 1.26A 6ew0I-5e7pA:
undetectable		 6ew0I-5e7pA:
7.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_B_BO2B201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A 188
THR A  66
THR A  65
ALA A  92
ALA A  68
 None
 1.02A 6hwdV-5e7pA:
undetectable
6hwdb-5e7pA:
undetectable		 6hwdV-5e7pA:
7.84
6hwdb-5e7pA:
8.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HWD_N_BO2N201_0
(PROTEASOME SUBUNIT
BETA TYPE-1
PROTEASOME SUBUNIT
BETA TYPE-2)		 5e7p CELL DIVISION
CONTROL PROTEIN
CDC48
(Mycolicibacteriu
m
smegmatis) 		5 / 12 THR A 188
THR A  66
THR A  65
ALA A  92
ALA A  68
 None
 1.03A 6hwdH-5e7pA:
undetectable
6hwdN-5e7pA:
undetectable		 6hwdH-5e7pA:
7.84
6hwdN-5e7pA:
8.00