SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e7q'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_A_SAMA105_0
(PROTEIN (MET
REPRESSOR))		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 8 ARG A  38
LEU A 148
GLU A 145
HIS A 134
 None
 0.82A 1cmaA-5e7qA:
undetectable
1cmaB-5e7qA:
undetectable		 1cmaA-5e7qA:
11.76
1cmaB-5e7qA:
11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTB_A_PZQA901_0
(GLUTATHIONE
S-TRANSFERASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		3 / 3 GLN A 220
TYR A 325
ARG A 335
 None
 0.89A 1gtbA-5e7qA:
undetectable		 1gtbA-5e7qA:
16.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 4 GLY A 152
LEU A 153
GLY A 151
ARG A  41
 None
 1.05A 1j7kA-5e7qA:
3.0		 1j7kA-5e7qA:
20.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KT6_A_RTLA184_0
(PLASMA
RETINOL-BINDING
PROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 11 LEU A  77
ALA A  22
LEU A  42
HIS A  13
ARG A  11
 None
 1.17A 1kt6A-5e7qA:
undetectable		 1kt6A-5e7qA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 6 ARG A  53
ILE A 160
GLY A  78
ALA A  79
 SO4  A 702 (-4.3A)
None
None
None
 0.98A 1wmqA-5e7qA:
undetectable		 1wmqA-5e7qA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 6 ARG A  53
ILE A 160
GLY A  78
ALA A  79
 SO4  A 702 (-4.3A)
None
None
None
 0.98A 1wmqB-5e7qA:
undetectable		 1wmqB-5e7qA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 6 ARG A  53
ILE A 160
GLY A  78
ALA A  79
 SO4  A 702 (-4.3A)
None
None
None
 0.96A 1wpuA-5e7qA:
undetectable		 1wpuA-5e7qA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 6 ARG A  53
ILE A 160
GLY A  78
ALA A  79
 SO4  A 702 (-4.3A)
None
None
None
 0.97A 1wpuB-5e7qA:
undetectable		 1wpuB-5e7qA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 6 ARG A  53
ILE A 160
GLY A  78
ALA A  79
 SO4  A 702 (-4.3A)
None
None
None
 0.96A 1wrqA-5e7qA:
undetectable		 1wrqA-5e7qA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 6 ARG A  53
ILE A 160
GLY A  78
ALA A  79
 SO4  A 702 (-4.3A)
None
None
None
 0.96A 1wrqB-5e7qA:
undetectable		 1wrqB-5e7qA:
15.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_A_CUA1599_0
(NITROUS OXIDE
REDUCTASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		3 / 3 CYH A 426
CYH A 471
HIS A 470
 None
 0.87A 2iwkA-5e7qA:
undetectable		 2iwkA-5e7qA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IWK_B_CUB1599_0
(NITROUS OXIDE
REDUCTASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		3 / 3 CYH A 426
CYH A 471
HIS A 470
 None
 0.85A 2iwkB-5e7qA:
undetectable		 2iwkB-5e7qA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QMZ_B_LDPB502_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 5 GLN A 220
PHE A 221
PHE A 300
GLY A 310
 None
SO4  A 709 (-4.7A)
SO4  A 709 (-4.8A)
None
 1.24A 2qmzA-5e7qA:
undetectable
2qmzB-5e7qA:
3.9		 2qmzA-5e7qA:
20.44
2qmzB-5e7qA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_B_ML1B233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 6 GLY A 310
GLY A 318
PHE A 221
PHE A 300
 None
None
SO4  A 709 (-4.7A)
SO4  A 709 (-4.8A)
 1.04A 2qx6A-5e7qA:
3.9
2qx6B-5e7qA:
3.9		 2qx6A-5e7qA:
20.44
2qx6B-5e7qA:
20.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_A_ASDA1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 8 ILE A 360
GLY A 393
ARG A 394
LEU A 404
 None
 0.64A 2vctA-5e7qA:
2.1		 2vctA-5e7qA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_B_ASDB1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 8 ILE A 360
GLY A 393
ARG A 394
LEU A 404
 None
 0.66A 2vctB-5e7qA:
undetectable		 2vctB-5e7qA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCT_C_ASDC1223_1
(GLUTATHIONE
S-TRANSFERASE A2)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 8 ILE A 360
GLY A 393
ARG A 394
LEU A 404
 None
 0.71A 2vctC-5e7qA:
2.1		 2vctC-5e7qA:
17.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 8 ILE A 216
GLY A 312
GLN A 313
THR A 314
 None
 0.26A 2wd9B-5e7qA:
25.8		 2wd9B-5e7qA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 10 THR A 171
ILE A 216
GLY A 312
GLN A 313
THR A 314
 None
 0.43A 2wd9C-5e7qA:
35.9		 2wd9C-5e7qA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2X2N_D_X2ND1479_1
(LANOSTEROL
14-ALPHA-DEMETHYLASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 ILE A 235
ALA A 333
ALA A 323
LEU A 198
MET A 191
 None
 1.18A 2x2nD-5e7qA:
undetectable		 2x2nD-5e7qA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FC6_C_REAC501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 VAL A  67
ALA A  73
ALA A  74
LEU A  42
ALA A  43
 None
 0.63A 3fc6C-5e7qA:
undetectable		 3fc6C-5e7qA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KW2_A_ADNA300_1
(PROBABLE R-RNA
METHYLTRANSFERASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 11 ALA A 320
SER A 317
LEU A 316
THR A 341
ALA A 362
 None
 1.25A 3kw2A-5e7qA:
undetectable		 3kw2A-5e7qA:
19.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MBG_C_ACTC800_0
(FAD-LINKED
SULFHYDRYL OXIDASE
ALR)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		3 / 3 ASP A 346
ARG A 350
ALA A 348
 None
SO4  A 705 (-3.4A)
None
 0.68A 3mbgC-5e7qA:
undetectable		 3mbgC-5e7qA:
14.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P97_C_SAMC263_0
(NON-STRUCTURAL
PROTEIN 5)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.88A 3p97C-5e7qA:
undetectable		 3p97C-5e7qA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QEO_B_LLTB261_1
(DEOXYCYTIDINE KINASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 7 VAL A 453
LEU A 503
TYR A 500
LEU A 411
 None
 1.06A 3qeoB-5e7qA:
undetectable		 3qeoB-5e7qA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A202_1
(POL POLYPROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 9 LEU A  46
ASP A 157
GLY A   7
ILE A   6
LEU A  42
 None
 0.98A 3u7sA-5e7qA:
undetectable		 3u7sA-5e7qA:
11.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTJ_C_SAMC1263_0
(NON-STRUCTURAL
PROTEIN 5)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.88A 4ctjC-5e7qA:
undetectable		 4ctjC-5e7qA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DTZ_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 8C8)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 6 ALA A 256
ALA A 282
PRO A 286
THR A 283
 None
 1.01A 4dtzA-5e7qA:
undetectable		 4dtzA-5e7qA:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4F3T_A_IPHA902_0
(PROTEIN ARGONAUTE-2)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 6 LEU A  42
LEU A 148
GLU A 145
TYR A 144
 None
 1.01A 4f3tA-5e7qA:
undetectable		 4f3tA-5e7qA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IIL_A_RBFA401_2
(MEMBRANE LIPOPROTEIN
TPN38(B))		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 8 PRO A 481
PRO A 473
GLN A 465
GLN A 429
 None
 1.03A 4iilA-5e7qA:
5.1		 4iilA-5e7qA:
22.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N09_A_ADNA401_1
(ADENOSINE KINASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 LEU A 198
GLY A 223
ASN A 233
ALA A 195
GLY A 231
 None
 1.13A 4n09A-5e7qA:
2.7		 4n09A-5e7qA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1Z_B_MXMB807_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 MET A 224
ILE A   6
VAL A 166
LEU A 188
PHE A 100
 None
 0.94A 4o1zB-5e7qA:
undetectable		 4o1zB-5e7qA:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_0
(PROLINE--TRNA LIGASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 LEU A 401
GLU A 351
VAL A 344
THR A 341
ARG A 343
 None
 1.36A 4q15A-5e7qA:
undetectable		 4q15A-5e7qA:
18.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WH5_A_3QBA204_1
(LINCOSAMIDE
RESISTANCE PROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A  52
ASP A  55
HIS A 103
PHE A 147
ALA A  48
 SO4  A 702 ( 3.8A)
SO4  A 707 (-4.7A)
SO4  A 707 (-4.1A)
None
None
 1.23A 4wh5A-5e7qA:
undetectable		 4wh5A-5e7qA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_C_ACTC403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 4 TYR A 144
GLY A 151
SER A  45
LEU A  42
 None
 1.30A 5bphC-5e7qA:
4.0		 5bphC-5e7qA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BPH_D_ACTD403_0
(D-ALANINE--D-ALANINE
LIGASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		4 / 6 TYR A 144
GLY A 151
SER A  45
LEU A  42
 None
 1.25A 5bphD-5e7qA:
4.1		 5bphD-5e7qA:
20.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_1
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		3 / 3 GLU A 359
HIS A 388
ASP A 346
 None
 0.79A 5c0oG-5e7qA:
undetectable		 5c0oG-5e7qA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E9Q_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.88A 5e9qC-5e7qA:
undetectable		 5e9qC-5e7qA:
17.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EC8_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.85A 5ec8C-5e7qA:
undetectable		 5ec8C-5e7qA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_A_SAMA301_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.89A 5ehgA-5e7qA:
undetectable		 5ehgA-5e7qA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHG_C_SAMC4001_0
(RNA-DIRECTED RNA
POLYMERASE NS5)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.88A 5ehgC-5e7qA:
undetectable		 5ehgC-5e7qA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_A_SAMA301_0
(GENOME POLYPROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.89A 5eifA-5e7qA:
undetectable		 5eifA-5e7qA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIF_C_SAMC4000_0
(GENOME POLYPROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.89A 5eifC-5e7qA:
undetectable		 5eifC-5e7qA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_B_SAMB4000_0
(NS5
METHYLTRANSFERASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.87A 5ekxB-5e7qA:
undetectable		 5ekxB-5e7qA:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKM_A_SAMA311_0
(NS5 METHYL
TRANSFERASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.90A 5ikmA-5e7qA:
undetectable		 5ikmA-5e7qA:
17.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQR_A_SAMA301_0
(METHYLTRANSFERASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.94A 5kqrA-5e7qA:
undetectable		 5kqrA-5e7qA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KQS_A_SAMA307_0
(GENOME POLYPROTEIN)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.91A 5kqsA-5e7qA:
undetectable		 5kqsA-5e7qA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M5B_A_SAMA1001_0
(NS5
METHYLTRANSFERASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.91A 5m5bA-5e7qA:
undetectable		 5m5bA-5e7qA:
18.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_A_SAMA301_0
(NS5)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.89A 5njvA-5e7qA:
undetectable		 5njvA-5e7qA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NJV_C_SAMC301_0
(NS5)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.85A 5njvC-5e7qA:
undetectable		 5njvC-5e7qA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UAH_C_RFPC3001_1
(DNA-DIRECTED RNA
POLYMERASE SUBUNIT
BETA)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 ARG A  38
LEU A  70
LEU A 104
ARG A 130
ILE A  51
 None
 1.27A 5uahC-5e7qA:
undetectable		 5uahC-5e7qA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_A_SAMA301_0
(METHYLTRANSFERASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.94A 5vimA-5e7qA:
undetectable		 5vimA-5e7qA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.90A 5vimB-5e7qA:
undetectable		 5vimB-5e7qA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_A_CVIA301_0
(REGULATORY PROTEIN
TETR)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 MET A 224
ALA A  72
LEU A 188
ILE A 189
ASP A 163
 None
 1.36A 5vlmA-5e7qA:
undetectable		 5vlmA-5e7qA:
16.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		3 / 3 THR A 205
THR A 254
ARG A 279
 None
 1.04A 5wm2A-5e7qA:
36.7		 5wm2A-5e7qA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		3 / 3 THR A 205
THR A 254
ARG A 281
 None
 0.71A 5wm2A-5e7qA:
36.7		 5wm2A-5e7qA:
28.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_A_SAMA601_0
(NS5 MTASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.91A 5wz2A-5e7qA:
undetectable		 5wz2A-5e7qA:
19.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 5e7q ACYL-COA SYNTHETASE
(Streptomyces
platensis) 		5 / 12 GLY A 308
GLY A 318
GLY A 312
GLY A 310
ILE A 216
 SO4  A 709 ( 3.9A)
None
None
None
None
 0.93A 5wz2C-5e7qA:
undetectable		 5wz2C-5e7qA:
19.48