SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e8e'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1AV2_D_DVAD8_0 (GRAMICIDIN A)	5e8e	IGA FAB HEAVY CHAIN (Homo sapiens)	3 / 3	VAL B 20 VAL B 83 TRP B 36	None	0.86A	1av2C-5e8eB: undetectable 1av2D-5e8eB: undetectable	1av2C-5e8eB: 5.39 1av2D-5e8eB: 5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1W5U_D_DVAD8_0 (GRAMICIDIN D)	5e8e	IGA FAB HEAVY CHAIN (Homo sapiens)	3 / 3	VAL B 20 VAL B 83 TRP B 36	None	0.92A	1w5uC-5e8eB: undetectable 1w5uD-5e8eB: undetectable	1w5uC-5e8eB: 5.39 1w5uD-5e8eB: 5.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E1Q_A_SALA2006_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	5e8e	IGA FAB HEAVY CHAIN (Homo sapiens)	4 / 6	ARG B 176 THR B 174 VAL B 173 LEU B 197	None	1.03A	2e1qA-5e8eB: undetectable	2e1qA-5e8eB: 9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2E1Q_C_SALC4006_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	5e8e	IGA FAB HEAVY CHAIN (Homo sapiens)	4 / 6	ARG B 176 THR B 174 VAL B 173 LEU B 197	None	0.99A	2e1qC-5e8eB: undetectable	2e1qC-5e8eB: 9.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_B_DVAB8_0 (GRAMICIDIN D)	5e8e	IGA FAB HEAVY CHAIN (Homo sapiens)	3 / 3	VAL B 20 VAL B 83 TRP B 36	None	0.89A	3l8lA-5e8eB: undetectable 3l8lB-5e8eB: undetectable	3l8lA-5e8eB: 5.39 3l8lB-5e8eB: 5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3L8L_D_DVAD8_0 (GRAMICIDIN D)	5e8e	IGA FAB HEAVY CHAIN (Homo sapiens)	3 / 3	VAL B 20 VAL B 83 TRP B 36	None	0.96A	3l8lC-5e8eB: undetectable 3l8lD-5e8eB: undetectable	3l8lC-5e8eB: 5.39 3l8lD-5e8eB: 5.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UNI_A_SALA1344_1 (XANTHINE DEHYDROGENASE/OXIDAS E)	5e8e	IGA FAB HEAVY CHAIN (Homo sapiens)	4 / 7	ARG B 176 THR B 174 VAL B 173 LEU B 197	None	0.94A	3uniA-5e8eB: undetectable	3uniA-5e8eB: 10.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGP_A_ERYA402_0 (MACROLIDE 2'-PHOSPHOTRANSFERAS E)	5e8e	IGA FAB HEAVY CHAIN (Homo sapiens)	5 / 12	VAL B 212 GLU B 168 ALA B 150 VAL B 153 LEU B 136	None	1.35A	5igpA-5e8eB: undetectable	5igpA-5e8eB: 20.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1AV2_D_DVAD8_0","GRAMICIDIN A","5e8e","IGA FAB HEAVY CHAIN","Homo sapiens",3,"VAL B  20;VAL B  83;TRP B  36","None","0.86A","1av2C-5e8eB:undetectable;1av2D-5e8eB:undetectable","1av2C-5e8eB:5.39;1av2D-5e8eB:5.39"],["1W5U_D_DVAD8_0","GRAMICIDIN D","5e8e","IGA FAB HEAVY CHAIN","Homo sapiens",3,"VAL B  20;VAL B  83;TRP B  36","None","0.92A","1w5uC-5e8eB:undetectable;1w5uD-5e8eB:undetectable","1w5uC-5e8eB:5.39;1w5uD-5e8eB:5.39"],["2E1Q_A_SALA2006_1","XANTHINE DEHYDROGENASE\/OXIDASE","5e8e","IGA FAB HEAVY CHAIN","Homo sapiens",4,"ARG B 176;THR B 174;VAL B 173;LEU B 197","None","1.03A","2e1qA-5e8eB:undetectable","2e1qA-5e8eB:9.90"],["2E1Q_C_SALC4006_1","XANTHINE DEHYDROGENASE\/OXIDASE","5e8e","IGA FAB HEAVY CHAIN","Homo sapiens",4,"ARG B 176;THR B 174;VAL B 173;LEU B 197","None","0.99A","2e1qC-5e8eB:undetectable","2e1qC-5e8eB:9.90"],["3L8L_B_DVAB8_0","GRAMICIDIN D","5e8e","IGA FAB HEAVY CHAIN","Homo sapiens",3,"VAL B  20;VAL B  83;TRP B  36","None","0.89A","3l8lA-5e8eB:undetectable;3l8lB-5e8eB:undetectable","3l8lA-5e8eB:5.39;3l8lB-5e8eB:5.56"],["3L8L_D_DVAD8_0","GRAMICIDIN D","5e8e","IGA FAB HEAVY CHAIN","Homo sapiens",3,"VAL B  20;VAL B  83;TRP B  36","None","0.96A","3l8lC-5e8eB:undetectable;3l8lD-5e8eB:undetectable","3l8lC-5e8eB:5.39;3l8lD-5e8eB:5.56"],["3UNI_A_SALA1344_1","XANTHINE DEHYDROGENASE\/OXIDASE","5e8e","IGA FAB HEAVY CHAIN","Homo sapiens",4,"ARG B 176;THR B 174;VAL B 173;LEU B 197","None","0.94A","3uniA-5e8eB:undetectable","3uniA-5e8eB:10.65"],["5IGP_A_ERYA402_0","MACROLIDE 2'-PHOSPHOTRANSFERASE","5e8e","IGA FAB HEAVY CHAIN","Homo sapiens",5,"VAL B 212;GLU B 168;ALA B 150;VAL B 153;LEU B 136","None","1.35A","5igpA-5e8eB:undetectable","5igpA-5e8eB:20.00"]]