SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e94'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7W_A_MTXA301_1
(PTERIDINE REDUCTASE)		 5e94 ANTIBODY FAB
FRAGMENT HEAVY CHAIN
(Mus
musculus) 		5 / 12 ARG B  67
PRO B  42
LEU B  20
LEU B  18
ASP B  90
 None
 1.13A 1e7wA-5e94B:
undetectable		 1e7wA-5e94B:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_A_CTXA11_1
(CES1 PROTEIN)		 5e94 ANTIBODY FAB
FRAGMENT HEAVY CHAIN
(Mus
musculus) 		4 / 8 PRO B 136
LEU B 199
GLY B 200
LEU B 148
 None
 0.83A 1ya4A-5e94B:
undetectable		 1ya4A-5e94B:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YA4_B_CTXB1283_1
(CES1 PROTEIN)		 5e94 ANTIBODY FAB
FRAGMENT HEAVY CHAIN
(Mus
musculus) 		4 / 7 PRO B 136
LEU B 199
GLY B 200
LEU B 148
 None
 0.93A 1ya4B-5e94B:
undetectable		 1ya4B-5e94B:
17.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB5_0
(FERROCHELATASE)		 5e94 ANTIBODY FAB
FRAGMENT HEAVY CHAIN
(Mus
musculus) 		3 / 3 PRO B   9
LEU B 119
ARG B  39
 None
 0.69A 3aqiB-5e94B:
undetectable		 3aqiB-5e94B:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_B_ADNB438_2
(ADENOSYLHOMOCYSTEINA
SE)		 5e94 ANTIBODY FAB
FRAGMENT HEAVY CHAIN
(Mus
musculus) 		3 / 3 THR B 120
GLU B 158
HIS B 210
 None
 0.83A 3g1uB-5e94B:
undetectable		 3g1uB-5e94B:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BPY_A_ACTA408_0
(THIOREDOXIN
REDUCTASE)		 5e94 ANTIBODY FAB
FRAGMENT HEAVY CHAIN
(Mus
musculus) 		3 / 3 PRO B 195
SER B 197
SER B 198
 None
 0.61A 6bpyA-5e94B:
undetectable		 6bpyA-5e94B:
21.01