SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5e9a'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HPK_A_ACAA80_1
(PLASMINOGEN)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 6 PRO A 279
ASP A 276
ASN A 253
TRP A 275
 None
 1.24A 1hpkA-5e9aA:
undetectable		 1hpkA-5e9aA:
8.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P2Y_A_NCTA440_1
(CYTOCHROME P450-CAM)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 7 LEU A  85
VAL A  49
GLY A  50
ASP A  70
 None
 0.44A 1p2yA-5e9aA:
undetectable		 1p2yA-5e9aA:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q23_E_FUAE706_1
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 10 PHE A 272
LEU A  15
VAL A  46
PHE A  84
VAL A 311
 None
 1.46A 1q23E-5e9aA:
undetectable		 1q23E-5e9aA:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T88_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 7 LEU A  85
VAL A  49
GLY A  50
ASP A  70
 None
 0.48A 1t88A-5e9aA:
undetectable		 1t88A-5e9aA:
21.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		3 / 3 GLN A 643
HIS A 344
ARG A 632
 None
 1.03A 1zlqA-5e9aA:
undetectable		 1zlqA-5e9aA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A1O_A_CAMA1422_0
(CYTOCHROME P450-CAM)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 8 LEU A  85
VAL A  49
GLY A  50
ASP A  70
 None
 0.64A 2a1oA-5e9aA:
undetectable		 2a1oA-5e9aA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXP_A_P1ZA3001_1
(SERUM ALBUMIN)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 LEU A 339
PHE A 641
LEU A 390
ALA A 397
ALA A 346
 None
 1.10A 2bxpA-5e9aA:
undetectable		 2bxpA-5e9aA:
21.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CBR_A_A80A201_1
(PROTEIN (CRABP-I))		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 PHE A 606
VAL A 448
VAL A 434
THR A 492
LEU A 543
 None
 1.05A 2cbrA-5e9aA:
undetectable		 2cbrA-5e9aA:
10.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DQY_C_CHDC3_0
(LIVER
CARBOXYLESTERASE 1)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 6 LEU A 654
LEU A 642
PRO A 624
VAL A 627
 None
 1.17A 2dqyC-5e9aA:
undetectable		 2dqyC-5e9aA:
22.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NMZ_B_ROCB401_2
(PROTEASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		3 / 3 ARG A 683
VAL A 652
THR A 621
 None
 0.65A 2nmzA-5e9aA:
undetectable		 2nmzA-5e9aA:
8.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 11 GLY A 151
ILE A  11
SER A   8
VAL A  46
ILE A  81
 None
 1.10A 2nnhA-5e9aA:
undetectable		 2nnhA-5e9aA:
20.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NPN_A_SAMA4633_0
(PUTATIVE COBALAMIN
SYNTHESIS RELATED
PROTEIN)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 9 LEU A 139
TYR A 143
THR A  87
ALA A  86
LEU A  73
 None
 1.27A 2npnA-5e9aA:
undetectable		 2npnA-5e9aA:
16.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 HIS A 532
SER A 552
ASN A 597
PRO A 548
GLY A 547
 None
 1.22A 2vmyB-5e9aA:
undetectable		 2vmyB-5e9aA:
19.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XKW_A_P1BA1478_2
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 7 LEU A 441
ILE A 464
ALA A 563
ILE A 519
 None
 0.69A 2xkwA-5e9aA:
undetectable		 2xkwA-5e9aA:
17.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YGO_A_PCFA1213_1
(WNT INHIBITORY
FACTOR 1)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 6 LEU A  76
ARG A 355
PRO A  22
VAL A 342
 None
 1.16A 2ygoA-5e9aA:
undetectable		 2ygoA-5e9aA:
14.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DZG_B_NCAB302_0
(ADP-RIBOSYL CYCLASE
1)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 7 GLU A 314
ASP A  19
SER A 274
THR A 251
 ACT  A 702 (-3.3A)
None
None
None
 1.24A 3dzgB-5e9aA:
2.4		 3dzgB-5e9aA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EIG_A_MTXA200_1
(DIHYDROFOLATE
REDUCTASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 ILE A 288
ALA A 291
LEU A 336
PRO A 674
ASN A 649
 None
 1.30A 3eigA-5e9aA:
undetectable		 3eigA-5e9aA:
14.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_4
(HIV-1 PROTEASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		3 / 3 ARG A 683
VAL A 652
THR A 621
 None
 0.73A 3k4vD-5e9aA:
undetectable		 3k4vD-5e9aA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K9F_H_LFXH0_1
(DNA TOPOISOMERASE 4
SUBUNIT A
DNA TOPOISOMERASE 4
SUBUNIT B)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 6 ARG A 105
ARG A 118
GLY A 117
GLU A 362
 None
ACT  A 702 (-3.2A)
None
ACT  A 702 (-3.0A)
 1.14A 3k9fA-5e9aA:
undetectable
3k9fB-5e9aA:
undetectable
3k9fD-5e9aA:
undetectable		 3k9fA-5e9aA:
22.66
3k9fB-5e9aA:
22.66
3k9fD-5e9aA:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		3 / 3 ARG A 683
VAL A 652
THR A 621
 None
 0.81A 3ndtA-5e9aA:
undetectable		 3ndtA-5e9aA:
10.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_A_SALA404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 7 ASN A 597
ALA A 551
TYR A 569
ALA A 579
 None
 0.95A 3twpA-5e9aA:
undetectable		 3twpA-5e9aA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_B_SALB404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 7 ASN A 597
ALA A 551
TYR A 569
ALA A 579
 None
 0.93A 3twpB-5e9aA:
2.0		 3twpB-5e9aA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_C_SALC404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 7 ASN A 597
ALA A 551
TYR A 569
ALA A 579
 None
 0.94A 3twpC-5e9aA:
2.1		 3twpC-5e9aA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TWP_D_SALD404_1
(ANTHRANILATE
PHOSPHORIBOSYLTRANSF
ERASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 5 ASN A 597
ALA A 551
TYR A 569
ALA A 579
 None
 0.96A 3twpD-5e9aA:
undetectable		 3twpD-5e9aA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UVV_B_9CRB501_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 ALA A 630
LEU A 642
ALA A 618
ILE A 389
LEU A 336
 None
 1.17A 3uvvB-5e9aA:
undetectable		 3uvvB-5e9aA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A79_A_P1BA601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 PRO A 578
LEU A 560
LEU A 517
ILE A 558
TYR A 592
 None
 1.38A 4a79A-5e9aA:
undetectable		 4a79A-5e9aA:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E7C_A_ACTA504_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		3 / 3 ARG A 224
TRP A 189
GLY A 217
 None
 0.66A 4e7cA-5e9aA:
undetectable		 4e7cA-5e9aA:
21.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_A_E20A604_1
(ACETYLCHOLINESTERASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 11 TYR A 158
GLY A 160
TYR A 261
HIS A 163
GLY A 107
 None
 1.36A 4ey7A-5e9aA:
undetectable		 4ey7A-5e9aA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EY7_B_E20B605_1
(ACETYLCHOLINESTERASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 11 TYR A 158
GLY A 160
TYR A 261
HIS A 163
GLY A 107
 None
 1.34A 4ey7B-5e9aA:
undetectable		 4ey7B-5e9aA:
23.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		3 / 3 PHE A 573
VAL A 557
GLU A 522
 None
 0.71A 4fvqA-5e9aA:
undetectable		 4fvqA-5e9aA:
16.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GRK_A_KTRA713_1
(LACTOTRANSFERRIN)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 5 THR A 501
GLY A 217
VAL A 215
TYR A 179
 None
 1.18A 4grkA-5e9aA:
undetectable		 4grkA-5e9aA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7U_D_YTZD802_1
(SEPIAPTERIN
REDUCTASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 8 SER A 495
LEU A 468
PHE A 489
TYR A 592
 None
 1.18A 4j7uD-5e9aA:
undetectable		 4j7uD-5e9aA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_A_SASA806_1
(SEPIAPTERIN
REDUCTASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 SER A   8
LEU A   7
PHE A  84
ASP A  19
GLY A  17
 None
 1.19A 4j7xA-5e9aA:
undetectable		 4j7xA-5e9aA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4J7X_F_SASF805_1
(SEPIAPTERIN
REDUCTASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 SER A   8
LEU A   7
PHE A  84
ASP A  19
GLY A  17
 None
 1.21A 4j7xF-5e9aA:
undetectable		 4j7xF-5e9aA:
19.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_A_5D5A930_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 LEU A 428
PRO A 466
ILE A 407
TRP A 415
ARG A 223
 None
 1.25A 5dlvA-5e9aA:
undetectable		 5dlvA-5e9aA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DLV_B_5D5B927_0
(ECTONUCLEOTIDE
PYROPHOSPHATASE/PHOS
PHODIESTERASE FAMILY
MEMBER 2)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 LEU A 428
PRO A 466
ILE A 407
TRP A 415
ARG A 223
 None
 1.25A 5dlvB-5e9aA:
undetectable		 5dlvB-5e9aA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H8T_A_RTLA201_0
(RETINOL-BINDING
PROTEIN 1)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 LEU A  73
LEU A  76
ALA A 148
ILE A 154
LEU A 241
 None
 1.08A 5h8tA-5e9aA:
undetectable		 5h8tA-5e9aA:
12.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNX_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 VAL A  83
LEU A 139
LEU A  57
THR A  65
PRO A  22
 None
 1.29A 5hnxB-5e9aA:
1.6		 5hnxB-5e9aA:
20.86
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 GLN A 350
VAL A  46
LEU A  76
VAL A  72
GLY A  50
 None
 1.40A 5i8fA-5e9aA:
undetectable		 5i8fA-5e9aA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I8F_A_ML1A210_1
(PHENOLIC OXIDATIVE
COUPLING PROTEIN)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 VAL A 463
PHE A 489
LEU A 468
VAL A 471
GLY A 474
 None
 1.37A 5i8fA-5e9aA:
undetectable		 5i8fA-5e9aA:
13.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODI_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		3 / 3 HIS A 559
GLU A 561
TRP A 520
 None
 1.28A 5odiD-5e9aA:
undetectable		 5odiD-5e9aA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ODQ_D_ACTD202_0
(METHYL-VIOLOGEN
REDUCING
HYDROGENASE, SUBUNIT
D)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		3 / 3 HIS A 559
GLU A 561
TRP A 520
 None
 1.20A 5odqD-5e9aA:
2.0		 5odqD-5e9aA:
11.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_A_NIZA810_1
(CATALASE-PEROXIDASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 6 HIS A 282
LEU A 290
PRO A 279
SER A 337
 None
 1.12A 5syjA-5e9aA:
undetectable		 5syjA-5e9aA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB810_1
(CATALASE-PEROXIDASE)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		4 / 6 HIS A 282
LEU A 290
PRO A 279
SER A 337
 None
 1.13A 5syjB-5e9aA:
undetectable		 5syjB-5e9aA:
22.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		3 / 3 THR A 294
MET A 296
HIS A 344
 None
 0.82A 5uunA-5e9aA:
undetectable		 5uunA-5e9aA:
18.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_B_HFGB802_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 GLU A 382
VAL A 379
PRO A 317
THR A 316
THR A 294
 None
 1.25A 5xioB-5e9aA:
2.6		 5xioB-5e9aA:
21.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XIO_B_HFGB802_0
(PROLINE-TRNA
SYNTHETASE CLASS II
AARS (YBAK RNA
BINDING DOMAIN PLUS
TRNA SYNTHETASE))		 5e9a BETA-GALACTOSIDASE
(Rahnella
sp.
R3) 		5 / 12 GLU A 382
VAL A 383
PRO A 317
THR A 316
THR A 283
 None
 1.28A 5xioB-5e9aA:
2.6		 5xioB-5e9aA:
21.69