SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ea0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5ea0 HEAVY CHAIN OF
ANTIBODY 7968 FAB
FRAGMENT
(Homo
sapiens) 		5 / 12 VAL H 165
VAL H 184
SER H 182
ASN H 199
ASN H 157
 None
 1.45A 2y03A-5ea0H:
undetectable		 2y03A-5ea0H:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_A_CHDA200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5ea0 HEAVY CHAIN OF
ANTIBODY 7968 FAB
FRAGMENT
(Homo
sapiens) 		4 / 5 PRO H 121
THR H 112
VAL H  11
GLY H  10
 None
 1.17A 3elzA-5ea0H:
undetectable		 3elzA-5ea0H:
21.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 5ea0 HEAVY CHAIN OF
ANTIBODY 7968 FAB
FRAGMENT
(Homo
sapiens) 		4 / 5 SER H 114
ALA H 116
PHE H 148
LEU H 172
 None
 0.41A 5mthA-5ea0H:
26.9		 5mthA-5ea0H:
53.10