SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ec1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ID5_B_SAMB301_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE)	5ec1	ANTIBODY FAB FRAGMENT LIGHT CHAIN (Mus musculus)	5 / 11	GLY B 30 ALA B 25 ASP B 32 ILE B 29 GLN B 27	None	1.36A	3id5B-5ec1B: undetectable	3id5B-5ec1B: 22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ID5_F_SAMF301_0 (FIBRILLARIN-LIKE RRNA/TRNA 2'-O-METHYLTRANSFERA SE)	5ec1	ANTIBODY FAB FRAGMENT LIGHT CHAIN (Mus musculus)	5 / 11	GLY B 30 ALA B 25 ASP B 32 ILE B 29 GLN B 27	None	1.36A	3id5F-5ec1B: undetectable	3id5F-5ec1B: 22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3JWQ_C_VIAC901_1 (CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA)	5ec1	ANTIBODY FAB FRAGMENT LIGHT CHAIN (Mus musculus)	4 / 7	TYR B 50 LEU B 4 GLN B 90 PHE B 96	None	1.03A	3jwqC-5ec1B: undetectable	3jwqC-5ec1B: 19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HSW_A_ACTA501_0 (ORF 37)	5ec1	ANTIBODY FAB FRAGMENT LIGHT CHAIN (Mus musculus)	4 / 5	ARG B 18 SER B 74 SER B 63 SER B 77	None	1.02A	5hswA-5ec1B: undetectable	5hswA-5ec1B: 17.97

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3ID5_B_SAMB301_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE","5ec1","ANTIBODY FAB FRAGMENT LIGHT CHAIN","Mus musculus",5,"GLY B  30;ALA B  25;ASP B  32;ILE B  29;GLN B  27","None","1.36A","3id5B-5ec1B:undetectable","3id5B-5ec1B:22.09"],["3ID5_F_SAMF301_0","FIBRILLARIN-LIKE RRNA\/TRNA 2'-O-METHYLTRANSFERASE","5ec1","ANTIBODY FAB FRAGMENT LIGHT CHAIN","Mus musculus",5,"GLY B  30;ALA B  25;ASP B  32;ILE B  29;GLN B  27","None","1.36A","3id5F-5ec1B:undetectable","3id5F-5ec1B:22.09"],["3JWQ_C_VIAC901_1","CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE CATALYTIC DOMAIN, CONE CGMP-SPECIFIC 3',5'-CYCLIC PHOSPHODIESTERASE SUBUNIT ALPHA CHIMERA","5ec1","ANTIBODY FAB FRAGMENT LIGHT CHAIN","Mus musculus",4,"TYR B  50;LEU B   4;GLN B  90;PHE B  96","None","1.03A","3jwqC-5ec1B:undetectable","3jwqC-5ec1B:19.88"],["5HSW_A_ACTA501_0","ORF 37","5ec1","ANTIBODY FAB FRAGMENT LIGHT CHAIN","Mus musculus",4,"ARG B  18;SER B  74;SER B  63;SER B  77","None","1.02A","5hswA-5ec1B:undetectable","5hswA-5ec1B:17.97"]]