SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ec5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM4_A_DXCA1002_0
(MAJOR POLLEN
ALLERGEN BET V 1-L)		 5ec5 LYSENIN
(Eisenia
fetida) 		5 / 12 VAL A 281
ILE A 170
ASN A 215
SER A 195
LEU A 192
 None
 1.22A 1fm4A-5ec5A:
undetectable		 1fm4A-5ec5A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PKV_A_RBFA100_1
(RIBOFLAVIN SYNTHASE
ALPHA CHAIN)		 5ec5 LYSENIN
(Eisenia
fetida) 		5 / 11 SER A 269
CYH A 283
LEU A 284
ILE A 232
VAL A 281
 MBO  A 301 (-2.8A)
MBO  A 301 (-2.2A)
MBO  A 302 (-4.6A)
None
None
 1.25A 1pkvA-5ec5A:
undetectable
1pkvB-5ec5A:
undetectable		 1pkvA-5ec5A:
14.14
1pkvB-5ec5A:
14.14