SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eco'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BRP_A_RTLA183_0
(RETINOL BINDING
PROTEIN)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		5 / 12 PHE A 545
ALA A 542
GLY A 537
PHE A 223
LEU A 419
 None
None
JAA  A 601 (-3.1A)
None
None
 1.20A 1brpA-5ecoA:
undetectable		 1brpA-5ecoA:
15.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C8L_A_CFFA940_1
(PROTEIN (GLYCOGEN
PHOSPHORYLASE))		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 6 PHE A 223
HIS A 229
ALA A 221
GLY A 303
 None
 1.08A 1c8lA-5ecoA:
undetectable		 1c8lA-5ecoA:
22.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_H_ACTH3006_0
(BETA-CARBONIC
ANHYDRASE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 6 GLN A 544
ASP A 405
VAL A 407
CYH A 423
 None
 1.36A 1ekjG-5ecoA:
undetectable
1ekjH-5ecoA:
undetectable		 1ekjG-5ecoA:
17.46
1ekjH-5ecoA:
17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GFZ_A_CFFA940_1
(GLYCOGEN
PHOSPHORYLASE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 6 PHE A 223
HIS A 229
ALA A 221
GLY A 303
 None
 1.09A 1gfzA-5ecoA:
undetectable		 1gfzA-5ecoA:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J96_B_TESB904_1
(3ALPHA-HYDROXYSTEROI
D DEHYDROGENASE TYPE
3)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		4 / 7 TYR B  32
ILE B 205
GLU B  34
TRP B  11
 None
 1.04A 1j96B-5ecoB:
undetectable		 1j96B-5ecoB:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RA8_A_FOLA161_1
(DIHYDROFOLATE
REDUCTASE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		3 / 3 ASP A  56
LYS A  62
ARG A 400
 None
 1.04A 1ra8A-5ecoA:
undetectable		 1ra8A-5ecoA:
14.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UOB_A_PNNA1311_0
(DEACETOXYCEPHALOSPOR
IN C SYNTHETASE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		5 / 12 SER A 151
LEU A 211
SER A 188
VAL A 192
ILE A 254
 None
 1.29A 1uobA-5ecoA:
undetectable		 1uobA-5ecoA:
23.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_A_ADNA433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		3 / 3 THR A 233
GLU A 480
HIS A 225
 None
 0.88A 1xwfA-5ecoA:
1.8		 1xwfA-5ecoA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_B_ADNB433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		3 / 3 THR A 233
GLU A 480
HIS A 225
 None
 0.87A 1xwfB-5ecoA:
undetectable		 1xwfB-5ecoA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_C_ADNC433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		3 / 3 THR A 233
GLU A 480
HIS A 225
 None
 0.89A 1xwfC-5ecoA:
2.7		 1xwfC-5ecoA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XWF_D_ADND433_2
(ADENOSYLHOMOCYSTEINA
SE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		3 / 3 THR A 233
GLU A 480
HIS A 225
 None
 0.88A 1xwfD-5ecoA:
undetectable		 1xwfD-5ecoA:
21.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AJV_L_COCL501_1
(ANTIBODY 7A1 FAB')		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		4 / 7 ALA B 166
TYR B 167
TYR B 208
TYR B  10
 None
 1.06A 2ajvH-5ecoB:
undetectable
2ajvL-5ecoB:
undetectable		 2ajvH-5ecoB:
19.42
2ajvL-5ecoB:
20.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AOF_C_FRDC305_1
(POL POLYPROTEIN
PEPTIDE INHIBITOR)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 5 GLY A  91
PRO A  95
ALA A  96
ILE A  97
 None
 0.95A 2aofA-5ecoA:
undetectable		 2aofA-5ecoA:
10.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FT9_A_CHDA130_0
(FATTY ACID-BINDING
PROTEIN 2, LIVER)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		5 / 12 PHE B 145
ILE B 175
SER B 179
ILE B 183
LEU B 157
 None
 1.04A 2ft9A-5ecoB:
undetectable		 2ft9A-5ecoB:
24.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QD3_A_CHDA501_0
(FERROCHELATASE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		5 / 11 LEU A 294
LEU A 290
LEU A 284
ARG A 213
ILE A 210
 None
 1.17A 2qd3A-5ecoA:
undetectable		 2qd3A-5ecoA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0M_C_KLNC1499_1
(CYTOCHROME P450 3A4)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		4 / 7 PHE B 106
LEU B 182
PHE B 164
ILE B 158
 None
 0.99A 2v0mC-5ecoB:
undetectable		 2v0mC-5ecoB:
18.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3E7G_D_H4BD3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		4 / 8 TRP B 163
PHE B 164
MET B  14
ILE B 158
 None
 1.17A 3e7gC-5ecoB:
undetectable
3e7gD-5ecoB:
undetectable		 3e7gC-5ecoB:
17.84
3e7gD-5ecoB:
17.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_A_H4BA1902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		4 / 7 MET B  14
ILE B 158
TRP B 163
PHE B 164
 None
 1.14A 3ej8A-5ecoB:
undetectable
3ej8B-5ecoB:
undetectable		 3ej8A-5ecoB:
17.56
3ej8B-5ecoB:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_B_H4BB2902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		4 / 7 TRP B 163
PHE B 164
MET B  14
ILE B 158
 None
 1.11A 3ej8A-5ecoB:
undetectable
3ej8B-5ecoB:
undetectable		 3ej8A-5ecoB:
17.56
3ej8B-5ecoB:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_C_H4BC3902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		4 / 7 MET B  14
ILE B 158
TRP B 163
PHE B 164
 None
 1.16A 3ej8C-5ecoB:
0.5
3ej8D-5ecoB:
undetectable		 3ej8C-5ecoB:
17.56
3ej8D-5ecoB:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EJ8_D_H4BD4902_1
(NITRIC OXIDE
SYNTHASE, INDUCIBLE)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		4 / 7 TRP B 163
PHE B 164
MET B  14
ILE B 158
 None
 1.15A 3ej8C-5ecoB:
0.5
3ej8D-5ecoB:
undetectable		 3ej8C-5ecoB:
17.56
3ej8D-5ecoB:
17.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_2
(PROTEASE)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		5 / 11 LEU B  68
GLY B  16
ALA B  19
VAL B  74
ILE B 158
 None
 1.15A 3ektD-5ecoB:
undetectable		 3ektD-5ecoB:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FSU_A_C2FA995_0
(5,10-METHYLENETETRAH
YDROFOLATE REDUCTASE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		5 / 12 ASN A 495
GLN A 491
LEU A 490
THR A 485
LEU A 497
 None
 1.12A 3fsuA-5ecoA:
undetectable		 3fsuA-5ecoA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GGU_B_017B201_1
(PROTEASE)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		5 / 12 LEU B  68
GLY B  16
ALA B  19
VAL B  74
ILE B 158
 None
 1.13A 3gguA-5ecoB:
undetectable		 3gguA-5ecoB:
14.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_C_CGEC501_1
(CYTOCHROME P450 2B4)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		5 / 9 VAL A 390
ILE A 337
PHE A 421
THR A 351
VAL A 354
 None
 1.21A 3me6C-5ecoA:
undetectable		 3me6C-5ecoA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		5 / 9 VAL A 390
ILE A 337
PHE A 421
THR A 351
VAL A 354
 None
 1.27A 3me6D-5ecoA:
undetectable		 3me6D-5ecoA:
22.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU6_B_478B401_2
(PROTEASE)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		5 / 10 LEU B  68
GLY B  16
ALA B  19
VAL B  74
ILE B 158
 None
 1.10A 3nu6B-5ecoB:
undetectable		 3nu6B-5ecoB:
15.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU9_A_478A401_2
(PROTEASE)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		5 / 10 LEU B  68
GLY B  16
ALA B  19
VAL B  74
ILE B 158
 None
 1.13A 3nu9B-5ecoB:
undetectable		 3nu9B-5ecoB:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RET_A_SALA201_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		5 / 10 VAL A 522
ALA A 448
VAL A 445
ILE A 477
ILE A 481
 None
 1.45A 3retA-5ecoA:
undetectable
3retB-5ecoA:
undetectable		 3retA-5ecoA:
11.83
3retB-5ecoA:
11.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_A_RBVA601_1
(RNA POLYMERASE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		5 / 9 SER A 150
THR A 166
THR A 164
ASN A 168
GLY A 163
 None
LEU  A 602 ( 3.0A)
LEU  A 602 (-4.7A)
None
None
 1.36A 3sfuA-5ecoA:
undetectable		 3sfuA-5ecoA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SFU_C_RBVC601_1
(RNA POLYMERASE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		5 / 11 SER A 150
THR A 166
THR A 164
ASN A 168
GLY A 163
 None
LEU  A 602 ( 3.0A)
LEU  A 602 (-4.7A)
None
None
 1.36A 3sfuC-5ecoA:
undetectable		 3sfuC-5ecoA:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UWL_B_FOZB316_0
(THYMIDYLATE SYNTHASE)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		5 / 12 ILE B 158
LEU B 135
GLY B 151
PHE B 150
ALA B  99
 None
 1.04A 3uwlB-5ecoB:
undetectable		 3uwlB-5ecoB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 8 GLN A 560
PHE A 113
GLY A 163
ASN A 174
 None
 0.95A 3v3nB-5ecoA:
undetectable		 3v3nB-5ecoA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 8 GLN A 560
PHE A 113
GLY A 163
ASN A 174
 None
 0.96A 3v3nC-5ecoA:
undetectable		 3v3nC-5ecoA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		4 / 6 ARG B  18
PRO B  55
GLU B  66
SER B  67
 None
None
None
GSH  B 301 (-3.2A)
 0.88A 3vlnA-5ecoB:
22.2		 3vlnA-5ecoB:
28.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		4 / 6 PHE B  15
ARG B  18
PRO B  55
SER B  67
 GSH  B 301 (-3.7A)
None
None
GSH  B 301 (-3.2A)
 0.39A 3vlnA-5ecoB:
22.2		 3vlnA-5ecoB:
28.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNV_D_QI9D602_0
(CYTOCHROME P450 2D6)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 7 PHE A  17
THR A 416
VAL A 341
PHE A 352
 None
 1.02A 4wnvD-5ecoA:
undetectable		 4wnvD-5ecoA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 4 VAL A 354
ALA A 339
PHE A  17
THR A 127
 None
 1.40A 4z4fA-5ecoA:
undetectable		 4z4fA-5ecoA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4H_A_IPHA903_0
(PROTEIN ARGONAUTE-2)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 4 VAL A 354
ALA A 339
PHE A  17
THR A 127
 None
 1.39A 4z4hA-5ecoA:
undetectable		 4z4hA-5ecoA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		3 / 3 TYR A 360
LYS A  33
LYS A  29
 None
 1.23A 5dbyA-5ecoA:
undetectable		 5dbyA-5ecoA:
22.89
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ECK_A_ILEA601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		6 / 6 ALA A 165
THR A 166
VAL A 169
TYR A 170
VAL A 222
HIS A 534
 LEU  A 602 (-3.1A)
LEU  A 602 ( 3.0A)
LEU  A 602 (-4.6A)
LEU  A 602 (-4.4A)
JAA  A 601 (-4.1A)
LEU  A 602 (-4.9A)
 0.53A 5eckA-5ecoA:
63.6		 5eckA-5ecoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ECK_D_ILED601_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		6 / 6 ALA A 165
THR A 166
VAL A 169
TYR A 170
VAL A 222
HIS A 534
 LEU  A 602 (-3.1A)
LEU  A 602 ( 3.0A)
LEU  A 602 (-4.6A)
LEU  A 602 (-4.4A)
JAA  A 601 (-4.1A)
LEU  A 602 (-4.9A)
 0.55A 5eckD-5ecoA:
62.7		 5eckD-5ecoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ECL_A_ILEA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		6 / 6 ALA A 165
THR A 166
VAL A 169
TYR A 170
VAL A 222
HIS A 534
 LEU  A 602 (-3.1A)
LEU  A 602 ( 3.0A)
LEU  A 602 (-4.6A)
LEU  A 602 (-4.4A)
JAA  A 601 (-4.1A)
LEU  A 602 (-4.9A)
 0.71A 5eclA-5ecoA:
59.3		 5eclA-5ecoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ECL_D_ILED602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		6 / 6 ILE A 148
ALA A 165
THR A 166
VAL A 169
VAL A 222
HIS A 534
 None
LEU  A 602 (-3.1A)
LEU  A 602 ( 3.0A)
LEU  A 602 (-4.6A)
JAA  A 601 (-4.1A)
LEU  A 602 (-4.9A)
 0.93A 5eclD-5ecoA:
56.9		 5eclD-5ecoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ECM_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		5 / 5 THR A 164
ALA A 165
THR A 166
TYR A 170
HIS A 534
 LEU  A 602 (-4.7A)
LEU  A 602 (-3.1A)
LEU  A 602 ( 3.0A)
LEU  A 602 (-4.4A)
LEU  A 602 (-4.9A)
 0.46A 5ecmA-5ecoA:
64.6		 5ecmA-5ecoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ECM_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		7 / 7 ALA A 165
THR A 166
VAL A 169
TYR A 170
VAL A 222
GLU A 533
HIS A 534
 LEU  A 602 (-3.1A)
LEU  A 602 ( 3.0A)
LEU  A 602 (-4.6A)
LEU  A 602 (-4.4A)
JAA  A 601 (-4.1A)
MG  A 603 (-3.9A)
LEU  A 602 (-4.9A)
 0.63A 5ecmD-5ecoA:
61.1		 5ecmD-5ecoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		6 / 7 ALA A 165
THR A 166
TYR A 170
VAL A 222
LYS A 530
GLU A 533
 LEU  A 602 (-3.1A)
LEU  A 602 ( 3.0A)
LEU  A 602 (-4.4A)
JAA  A 601 (-4.1A)
None
MG  A 603 (-3.9A)
 0.76A 5ecnA-5ecoA:
61.4		 5ecnA-5ecoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ECN_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		5 / 7 THR A 166
TYR A 170
VAL A 222
GLU A 533
HIS A 534
 LEU  A 602 ( 3.0A)
LEU  A 602 (-4.4A)
JAA  A 601 (-4.1A)
MG  A 603 (-3.9A)
LEU  A 602 (-4.9A)
 1.16A 5ecnA-5ecoA:
61.4		 5ecnA-5ecoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ECO_A_LEUA602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		6 / 6 THR A 164
ALA A 165
THR A 166
VAL A 169
TYR A 170
HIS A 534
 LEU  A 602 (-4.7A)
LEU  A 602 (-3.1A)
LEU  A 602 ( 3.0A)
LEU  A 602 (-4.6A)
LEU  A 602 (-4.4A)
LEU  A 602 (-4.9A)
 0.03A 5ecoA-5ecoA:
72.2		 5ecoA-5ecoA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5ECO_D_LEUD602_0
(JASMONIC ACID-AMIDO
SYNTHETASE JAR1)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		7 / 7 ALA A 165
THR A 166
VAL A 169
TYR A 170
VAL A 222
GLU A 533
HIS A 534
 LEU  A 602 (-3.1A)
LEU  A 602 ( 3.0A)
LEU  A 602 (-4.6A)
LEU  A 602 (-4.4A)
JAA  A 601 (-4.1A)
MG  A 603 (-3.9A)
LEU  A 602 (-4.9A)
 0.70A 5ecoD-5ecoA:
61.9		 5ecoD-5ecoA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FXT_A_0LAA1376_1
(DNA POLYMERASE III
SUBUNIT BETA)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 7 LYS A 265
LEU A 266
PRO A 189
LEU A 206
 None
 0.97A 5fxtA-5ecoA:
undetectable		 5fxtA-5ecoA:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J7W_D_MTXD402_1
(THYMIDYLATE SYNTHASE)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		5 / 12 ILE B 158
LEU B 135
GLY B 151
PHE B 150
ALA B  99
 None
 1.05A 5j7wD-5ecoB:
undetectable		 5j7wD-5ecoB:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0O_A_SAMA501_1
(PEPTIDE
N-METHYLTRANSFERASE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		3 / 3 ALA A 339
GLN A 123
THR A 127
 None
 0.75A 5n0oA-5ecoA:
undetectable		 5n0oA-5ecoA:
19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CJK_C_ACTC301_0
(IMMUNOGLOBULIN FAB
LIGHT CHAIN)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 4 VAL A 160
GLY A 158
ASP A  82
ASP A  84
 None
 0.96A 6cjkC-5ecoA:
undetectable		 6cjkC-5ecoA:
16.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6G2P_A_TRPA502_0
(FLAVIN-DEPENDENT
L-TRYPTOPHAN OXIDASE
VIOA)		 5eco GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana) 		4 / 7 TYR B  73
HIS B  59
LEU B  23
VAL B  28
 None
 1.30A 6g2pA-5ecoB:
undetectable		 6g2pA-5ecoB:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 5 GLY A 163
THR A 164
SER A 151
SER A 150
 None
LEU  A 602 (-4.7A)
None
None
 0.95A 6jmjA-5ecoA:
undetectable		 6jmjA-5ecoA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JNH_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 7 GLY A 163
THR A 164
SER A 151
SER A 150
 None
LEU  A 602 (-4.7A)
None
None
 0.95A 6jnhA-5ecoA:
undetectable		 6jnhA-5ecoA:
15.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NM4_A_SAMA402_0
(HISTONE-LYSINE
N-METHYLTRANSFERASE
PRDM9)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
GLUTATHIONE
S-TRANSFERASE U20
(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		4 / 7 ALA A 396
GLY A 397
LEU A  89
GLY B 140
 None
 0.75A 6nm4A-5ecoA:
undetectable		 6nm4A-5ecoA:
15.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5eco JASMONIC ACID-AMIDO
SYNTHETASE JAR1
(Arabidopsis
thaliana) 		4 / 5 LEU A 419
GLN A 418
PHE A 352
PHE A 361
 None
 1.31A 6nmpP-5ecoA:
undetectable
6nmpW-5ecoA:
undetectable		 6nmpP-5ecoA:
18.30
6nmpW-5ecoA:
7.95