SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5edj'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 8 ILE A  72
PHE A  63
ARG A  79
THR A  81
 None
 0.85A 2eijN-5edjA:
undetectable
2eijW-5edjA:
undetectable		 2eijN-5edjA:
16.42
2eijW-5edjA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 8 ILE A  72
PHE A  63
ARG A  79
THR A  81
 None
 0.86A 2eikN-5edjA:
undetectable
2eikW-5edjA:
undetectable		 2eikN-5edjA:
16.42
2eikW-5edjA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 8 ILE A  72
PHE A  63
ARG A  79
THR A  81
 None
 0.83A 2eilN-5edjA:
undetectable
2eilW-5edjA:
undetectable		 2eilN-5edjA:
16.42
2eilW-5edjA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_W_CHDW1060_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 8 ILE A  72
PHE A  63
ARG A  79
THR A  81
 None
 0.87A 3ablN-5edjA:
undetectable
3ablW-5edjA:
undetectable		 3ablN-5edjA:
16.42
3ablW-5edjA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 7 ILE A  72
PHE A  63
ARG A  79
THR A  81
 None
 0.92A 3ag2N-5edjA:
undetectable
3ag2W-5edjA:
undetectable		 3ag2N-5edjA:
16.42
3ag2W-5edjA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG4_W_CHDW1059_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE 7A1
CYTOCHROME C OXIDASE
SUBUNIT 1)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 7 ILE A  72
PHE A  63
ARG A  79
THR A  81
 None
 0.89A 3ag4N-5edjA:
undetectable
3ag4W-5edjA:
undetectable		 3ag4N-5edjA:
16.42
3ag4W-5edjA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_W_CHDW1059_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 8 ILE A  72
PHE A  63
ARG A  79
THR A  81
 None
 0.86A 3asnN-5edjA:
undetectable
3asnW-5edjA:
undetectable		 3asnN-5edjA:
16.42
3asnW-5edjA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IA4_A_MTXA164_2
(DIHYDROFOLATE
REDUCTASE)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 4 ILE A 145
PHE A  65
ILE A 103
THR A 232
 None
 1.15A 3ia4A-5edjA:
undetectable		 3ia4A-5edjA:
19.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ILT_H_TRUH800_1
(GLUTAMATE RECEPTOR 2)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		3 / 3 ILE A 239
SER A 221
SER A 223
 None
 0.53A 3iltH-5edjA:
undetectable		 3iltH-5edjA:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UZZ_B_ASDB501_1
(3-OXO-5-BETA-STEROID
4-DEHYDROGENASE)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 8 TYR A 235
HIS A 254
LEU A 152
MET A 156
 None
 1.44A 3uzzB-5edjA:
undetectable		 3uzzB-5edjA:
20.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A9J_C_TYLC1184_1
(BROMODOMAIN
CONTAINING 2)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 5 VAL A  61
LEU A  77
LEU A  89
ILE A 100
 None
 0.89A 4a9jC-5edjA:
undetectable		 4a9jC-5edjA:
23.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 6 ILE A  72
PHE A  63
ARG A  79
THR A  81
 None
 0.96A 5b1aN-5edjA:
undetectable
5b1aW-5edjA:
undetectable		 5b1aN-5edjA:
16.42
5b1aW-5edjA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 7 ILE A  72
PHE A  63
ARG A  79
THR A  81
 None
 0.86A 5b3sN-5edjA:
undetectable
5b3sW-5edjA:
undetectable		 5b3sN-5edjA:
16.42
5b3sW-5edjA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 7 ILE A  72
PHE A  63
ARG A  79
THR A  81
 None
 0.84A 5iy5N-5edjA:
undetectable
5iy5W-5edjA:
undetectable		 5iy5N-5edjA:
16.42
5iy5W-5edjA:
11.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KXI_A_NCTA402_1
(NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
ALPHA-4
NEURONAL
ACETYLCHOLINE
RECEPTOR SUBUNIT
BETA-2)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 8 TYR A 109
THR A 222
TRP A 116
LEU A 245
 None
 1.18A 5kxiA-5edjA:
undetectable
5kxiB-5edjA:
undetectable		 5kxiA-5edjA:
20.05
5kxiB-5edjA:
19.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT VIIA-HEART)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 8 ILE A  72
PHE A  63
ARG A  79
THR A  81
 None
 0.85A 5xdxN-5edjA:
undetectable
5xdxW-5edjA:
undetectable		 5xdxN-5edjA:
16.42
5xdxW-5edjA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 5 ILE A  72
PHE A  63
ARG A  79
THR A  81
 None
 0.85A 5z84N-5edjA:
undetectable
5z84W-5edjA:
undetectable		 5z84N-5edjA:
16.42
5z84W-5edjA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		4 / 5 ILE A  72
PHE A  63
TYR A  80
ARG A  79
 None
 1.31A 5z84N-5edjA:
undetectable
5z84W-5edjA:
undetectable		 5z84N-5edjA:
16.42
5z84W-5edjA:
12.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW2_A_ACTA511_0
(L-PROLYL-[PEPTIDYL-C
ARRIER PROTEIN]
DEHYDROGENASE)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		3 / 3 ARG A 240
ILE A 239
SER A 139
 None
 0.81A 5zw2A-5edjA:
undetectable		 5zw2A-5edjA:
19.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GBF_A_ACTA507_0
(MOLYBDOPTERIN
BIOSYNTHESIS PROTEIN
CNX1)		 5edj FRPC OPERON PROTEIN
(Neisseria
meningitidis) 		3 / 3 LYS A  87
SER A  90
SER A  47
 None
 1.11A 6gbfA-5edjA:
undetectable		 6gbfA-5edjA:
19.22