SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5edv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JX1_E_CAME502_0
(CAMPHOR
5-MONOOXYGENASE)		 5edv E3 UBIQUITIN-PROTEIN
LIGASE RNF31
(Homo
sapiens) 		4 / 5 PHE A 762
TYR A 761
THR A 753
ILE A 739
 None
 1.25A 4jx1E-5edvA:
undetectable		 4jx1E-5edvA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_0
(CYTOCHROME P450 1A1)		 5edv E3 UBIQUITIN-PROTEIN
LIGASE RNF31
(Homo
sapiens) 		5 / 12 ILE A 739
PHE A 762
LEU A 769
PHE A 730
ASP A 741
 None
 1.40A 6dwnB-5edvA:
undetectable		 6dwnB-5edvA:
11.60