SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ee0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OQ5_A_CELA701_2
(CARBONIC ANHYDRASE
II)		 5ee0 OBG-LIKE ATPASE 1
(Oryza
sativa) 		4 / 4 HIS A 124
VAL A  30
THR A 149
LEU A 108
 None
 1.27A 1oq5A-5ee0A:
undetectable		 1oq5A-5ee0A:
20.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 5ee0 OBG-LIKE ATPASE 1
(Oryza
sativa) 		5 / 12 LEU A  47
VAL A  66
ILE A 295
SER A 289
LEU A 228
 None
 0.92A 1s19A-5ee0A:
undetectable		 1s19A-5ee0A:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XZX_X_T3X500_1
(THYROID HORMONE
RECEPTOR BETA-1)		 5ee0 OBG-LIKE ATPASE 1
(Oryza
sativa) 		5 / 12 ILE A  95
ILE A  29
LEU A  90
ILE A 302
PHE A  40
 None
 1.24A 1xzxX-5ee0A:
undetectable		 1xzxX-5ee0A:
21.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2A3A_A_TEPA1436_1
(CHITINASE)		 5ee0 OBG-LIKE ATPASE 1
(Oryza
sativa) 		3 / 3 ASP A  70
PHE A 308
ARG A  72
 None
 0.81A 2a3aA-5ee0A:
2.3		 2a3aA-5ee0A:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_B_30BB500_1
(GENOME POLYPROTEIN)		 5ee0 OBG-LIKE ATPASE 1
(Oryza
sativa) 		5 / 12 GLN A 369
VAL A 376
GLY A 371
ALA A 330
ALA A 329
 None
 1.08A 3keeB-5ee0A:
undetectable		 3keeB-5ee0A:
17.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 5ee0 OBG-LIKE ATPASE 1
(Oryza
sativa) 		3 / 3 LEU A 154
ARG A 155
ARG A 202
 None
 0.88A 4yiaB-5ee0A:
undetectable		 4yiaB-5ee0A:
8.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZF8_A_MYTA502_1
(BIFUNCTIONAL
P-450/NADPH-P450
REDUCTASE)		 5ee0 OBG-LIKE ATPASE 1
(Oryza
sativa) 		4 / 6 VAL A 226
LEU A  90
ILE A 302
ALA A 301
 None
 0.76A 4zf8A-5ee0A:
undetectable		 4zf8A-5ee0A:
23.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZC_E_ACTE406_0
(PROTON-GATED ION
CHANNEL)		 5ee0 OBG-LIKE ATPASE 1
(Oryza
sativa) 		4 / 5 ILE A 122
ARG A 202
TYR A 227
GLU A 257
 None
 1.17A 4zzcE-5ee0A:
2.5		 4zzcE-5ee0A:
22.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FSA_B_X2NB590_1
(CYP51 VARIANT1)		 5ee0 OBG-LIKE ATPASE 1
(Oryza
sativa) 		5 / 12 GLY A  19
LEU A  90
PHE A 123
THR A 258
HIS A 303
 None
 1.25A 5fsaB-5ee0A:
undetectable		 5fsaB-5ee0A:
24.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0T_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5ee0 OBG-LIKE ATPASE 1
(Oryza
sativa) 		5 / 12 ILE A  27
GLY A 298
PHE A  40
ILE A  95
VAL A  30
 None
 0.95A 5n0tB-5ee0A:
undetectable		 5n0tB-5ee0A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_B_SAMB301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5ee0 OBG-LIKE ATPASE 1
(Oryza
sativa) 		5 / 12 LEU A 220
GLY A 107
THR A 149
VAL A 225
ILE A 116
 None
 0.97A 6emuB-5ee0A:
undetectable		 6emuB-5ee0A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EMU_C_SAMC301_0
(TRNA
(GUANINE(9)-/ADENINE
(9)-N1)-METHYLTRANSF
ERASE)		 5ee0 OBG-LIKE ATPASE 1
(Oryza
sativa) 		5 / 12 LEU A 220
GLY A 107
THR A 149
VAL A 225
ILE A 116
 None
 0.94A 6emuC-5ee0A:
undetectable		 6emuC-5ee0A:
20.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 5ee0 OBG-LIKE ATPASE 1
(Oryza
sativa) 		4 / 5 GLY A 331
THR A 332
SER A  22
SER A  23
 None
 1.10A 6jmjA-5ee0A:
undetectable		 6jmjA-5ee0A:
19.48