SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ee2'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SDT_B_MK1B902_1
(PROTEASE RETROPEPSIN)		 5ee2 HEMOGLOBIN-HAPTOGLOB
IN-UTILIZATION
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 10 ILE A 305
GLY A 306
GLY A 307
VAL A 262
ILE A 264
 None
 0.88A 1sdtA-5ee2A:
undetectable		 1sdtA-5ee2A:
21.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BWC_B_SAMB501_0
(SPERMIDINE SYNTHASE)		 5ee2 HEMOGLOBIN-HAPTOGLOB
IN-UTILIZATION
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 ILE A 252
GLY A 254
ASP A 257
GLY A 205
ASP A 261
 None
 0.99A 3bwcB-5ee2A:
undetectable		 3bwcB-5ee2A:
19.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_2
(PROTEASE)		 5ee2 HEMOGLOBIN-HAPTOGLOB
IN-UTILIZATION
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 10 ILE A 305
GLY A 306
GLY A 307
VAL A 262
ILE A 264
 None
 0.84A 3em4V-5ee2A:
undetectable		 3em4V-5ee2A:
23.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_A_D16A530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5ee2 HEMOGLOBIN-HAPTOGLOB
IN-UTILIZATION
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 SER A 325
ILE A 199
ASN A 242
ASP A 331
LEU A 330
 None
 1.13A 3nrrA-5ee2A:
undetectable		 3nrrA-5ee2A:
16.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NRR_B_D16B530_1
(DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 5ee2 HEMOGLOBIN-HAPTOGLOB
IN-UTILIZATION
PROTEIN
(Neisseria
gonorrhoeae) 		5 / 12 SER A 325
ILE A 199
ASN A 242
ASP A 331
LEU A 330
 None
 1.12A 3nrrB-5ee2A:
undetectable		 3nrrB-5ee2A:
16.38