SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eeb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPT_A_SAMA400_1
(VP39)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		3 / 3 ASP A 405
ARG A 374
ASP A 407
 None
 0.80A 1vptA-5eebA:
undetectable		 1vptA-5eebA:
19.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2887_1
(AMINOMETHYLTRANSFERA
SE)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		3 / 3 ASP A 472
GLU A 463
ARG A  70
 None
 0.82A 1wopA-5eebA:
undetectable		 1wopA-5eebA:
21.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 6 MET A  77
VAL A  80
PHE A  88
MET A 162
 None
 1.15A 1x8vA-5eebA:
undetectable		 1x8vA-5eebA:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZSE_A_PAUA600_0
(PANTOTHENATE KINASE)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 7 PHE A  81
MET A  84
PHE A  88
ILE A 114
 None
 1.11A 2zseA-5eebA:
undetectable		 2zseA-5eebA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_A_30BA500_1
(GENOME POLYPROTEIN)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		5 / 12 GLY A 146
GLY A 149
ARG A 223
ALA A  51
ASP A  53
 None
 1.10A 3keeA-5eebA:
undetectable		 3keeA-5eebA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEE_D_30BD500_1
(GENOME POLYPROTEIN)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		5 / 12 GLY A 146
GLY A 149
ARG A 223
ALA A  51
ASP A  53
 None
 1.13A 3keeD-5eebA:
undetectable		 3keeD-5eebA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7S_A_SAMA300_0
(PUTATIVE
METHYLTRANSFERASE)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		5 / 12 GLY A 450
GLY A 456
SER A 411
MET A 433
GLU A 468
 None
 1.19A 3t7sA-5eebA:
4.1		 3t7sA-5eebA:
18.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K0B_B_SAMB504_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 8 PRO A  20
ASP A  47
ALA A  51
SER A  43
 None
 1.06A 4k0bB-5eebA:
undetectable		 4k0bB-5eebA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L7I_B_SAMB501_1
(S-ADENOSYLMETHIONINE
SYNTHASE)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 8 PRO A  20
ASP A  47
ALA A  51
SER A  43
 None
 1.06A 4l7iB-5eebA:
undetectable		 4l7iB-5eebA:
21.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB301_1
(CHITOSANASE)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		3 / 3 GLY A 328
PRO A 329
GLN A 285
 None
 0.42A 4oltB-5eebA:
undetectable		 4oltB-5eebA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_B_GCSB305_1
(CHITOSANASE)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		3 / 3 GLY A 328
PRO A 329
GLN A 285
 None
 0.31A 4qwpB-5eebA:
0.8		 4qwpB-5eebA:
21.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QZU_C_ACTC202_0
(RETINOL-BINDING
PROTEIN 2)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 6 TYR A 177
GLU A  95
THR A 183
LEU A 206
 None
 1.24A 4qzuC-5eebA:
undetectable		 4qzuC-5eebA:
13.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_D_ADND303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		5 / 10 GLY A 236
SER A 233
ALA A 180
ILE A 151
PRO A 153
 None
 0.94A 4xj7C-5eebA:
3.4
4xj7D-5eebA:
3.3		 4xj7C-5eebA:
21.03
4xj7D-5eebA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJE_A_TOYA202_1
(AADB)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 8 ASP A 264
ASP A 265
ILE A 261
ASP A 396
 None
 0.89A 4xjeA-5eebA:
undetectable		 4xjeA-5eebA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CDN_O_EVPO2101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT
B,DNA GYRASE SUBUNIT
B)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 6 SER A 159
GLU A 106
GLY A 458
GLY A 450
 None
 0.89A 5cdnC-5eebA:
undetectable
5cdnD-5eebA:
undetectable		 5cdnC-5eebA:
22.50
5cdnD-5eebA:
17.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CFS_A_TOYA203_1
(AAD(2''),GENTAMICIN
2''-NUCLEOTIDYLTRANS
FERASE,GENTAMICIN
RESISTANCE PROTEIN)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 8 ASP A 264
ASP A 265
ILE A 261
ASP A 396
 None
 1.00A 5cfsA-5eebA:
undetectable		 5cfsA-5eebA:
17.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_4_BEZ4801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 5 LEU A 260
PHE A 434
ILE A 261
ILE A 425
 None
 0.79A 5dzk4-5eebA:
undetectable
5dzkg-5eebA:
undetectable
5dzkm-5eebA:
undetectable
5dzkn-5eebA:
undetectable		 5dzk4-5eebA:
0.56
5dzkg-5eebA:
18.33
5dzkm-5eebA:
18.74
5dzkn-5eebA:
18.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 6 PHE A 277
SER A 289
ALA A 290
LEU A 280
 None
 1.28A 5dzkB-5eebA:
undetectable
5dzkP-5eebA:
undetectable		 5dzkB-5eebA:
18.33
5dzkP-5eebA:
0.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_U_BEZU801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 6 PHE A 277
SER A 289
ALA A 290
LEU A 280
 None
 1.30A 5dzkg-5eebA:
undetectable
5dzku-5eebA:
undetectable		 5dzkg-5eebA:
18.33
5dzku-5eebA:
0.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Y_BEZY801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 1
ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 5 PHE A 434
ILE A 261
ILE A 425
LEU A 260
 None
 0.79A 5dzkd-5eebA:
undetectable
5dzkk-5eebA:
undetectable
5dzky-5eebA:
undetectable		 5dzkd-5eebA:
18.33
5dzkk-5eebA:
18.74
5dzky-5eebA:
0.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HW8_C_FK5C201_1
(FK506-BINDING
PROTEIN 1)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		5 / 10 TYR A 307
VAL A 295
ILE A 262
LEU A 274
ILE A 378
 None
 1.07A 5hw8C-5eebA:
undetectable
5hw8H-5eebA:
undetectable		 5hw8C-5eebA:
12.47
5hw8H-5eebA:
12.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IMS_A_ACTA708_0
(ACETOLACTATE
SYNTHASE CATALYTIC
SUBUNIT,
MITOCHONDRIAL)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		3 / 3 GLY A  96
GLY A  97
GLN A 285
 None
 0.49A 5imsA-5eebA:
3.1		 5imsA-5eebA:
22.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OY0_2_PQN2843_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		5 / 12 ILE A  65
ILE A 165
ALA A 166
LEU A  74
ALA A 118
 None
 1.28A 5oy02-5eebA:
undetectable		 5oy02-5eebA:
10.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Q1S_A_AWYA1103_0
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 6 LYS A   6
VAL A 185
ILE A  37
LYS A  90
 None
 1.36A 5q1sA-5eebA:
undetectable		 5q1sA-5eebA:
18.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VEU_H_RITH602_2
(CYTOCHROME P450 3A5)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		4 / 5 PHE A 363
PHE A 364
LEU A 330
LEU A 314
 None
 1.32A 5veuH-5eebA:
undetectable		 5veuH-5eebA:
22.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZJI_B_PQNB842_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		5 / 10 ILE A  65
ILE A 165
ALA A 166
LEU A  74
ALA A 118
 None
 1.28A 5zjiB-5eebA:
undetectable		 5zjiB-5eebA:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_B_RFPB502_1
(RIFAMPIN
MONOOXYGENASE)		 5eeb ALDEHYDE
DEHYDROGENASE
(Pyrobaculum
ferrireducens) 		5 / 12 GLY A 187
VAL A 185
THR A  93
GLY A  98
GLY A  97
 None
 1.13A 6brdB-5eebA:
undetectable		 6brdB-5eebA:
9.75