SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5efv'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IBG_H_OBNH1_1
(IGG2B-KAPPA 40-50
FAB (HEAVY CHAIN))		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		4 / 6 LEU A 156
PHE A 167
TYR A 342
VAL A 169
 None
 1.23A 1ibgH-5efvA:
undetectable		 1ibgH-5efvA:
15.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		3 / 3 GLY A  86
GLU A  91
ASN A  85
 None
 0.54A 1zq9A-5efvA:
undetectable		 1zq9A-5efvA:
17.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2F7F_A_NIOA601_1
(NICOTINATE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		4 / 6 ARG A 137
GLY A 398
THR A 397
ARG A 399
 None
 1.06A 2f7fA-5efvA:
undetectable		 2f7fA-5efvA:
21.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_A_SVRA508_1
(PHOSPHOLIPASE A2)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		4 / 5 VAL A 426
GLN A 148
PHE A 152
ARG A 142
 None
 0.93A 3bjwE-5efvA:
undetectable		 3bjwE-5efvA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC505_2
(PHOSPHOLIPASE A2)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		4 / 5 VAL A 426
GLN A 148
PHE A 152
ARG A 142
 None
 0.92A 3bjwH-5efvA:
undetectable		 3bjwH-5efvA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_C_SVRC507_2
(PHOSPHOLIPASE A2)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		4 / 6 VAL A 426
GLN A 148
PHE A 152
ARG A 142
 None
 1.06A 3bjwF-5efvA:
undetectable		 3bjwF-5efvA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		4 / 5 VAL A 426
GLN A 148
PHE A 152
ARG A 142
 None
 0.87A 3bjwB-5efvA:
undetectable		 3bjwB-5efvA:
10.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CO4_A_GCSA401_1
(CHITINASE)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		3 / 3 GLU A 385
HIS A 415
HIS A 416
 None
 0.91A 3co4A-5efvA:
undetectable		 3co4A-5efvA:
18.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		5 / 12 GLY A 405
ALA A 386
ILE A 418
LEU A 389
ILE A 176
 None
 1.09A 4aztA-5efvA:
undetectable		 4aztA-5efvA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_0U9A601_1
(CHOLESTEROL
24-HYDROXYLASE)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		5 / 12 TYR A 392
LEU A 403
PHE A 167
VAL A 169
GLU A 151
 None
 1.30A 4fiaA-5efvA:
undetectable		 4fiaA-5efvA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FIA_A_198A602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		5 / 12 TYR A 392
LEU A 403
PHE A 167
VAL A 169
GLU A 151
 None
 1.30A 4fiaA-5efvA:
undetectable		 4fiaA-5efvA:
20.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		4 / 6 THR A 323
GLN A 355
THR A 211
HIS A 212
 None
 1.26A 4pfjB-5efvA:
undetectable		 4pfjB-5efvA:
20.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C6P_A_4YHA601_1
(PROTEIN C)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		4 / 6 ALA A 227
SER A 267
GLN A 165
SER A 166
 None
 1.07A 5c6pA-5efvA:
undetectable		 5c6pA-5efvA:
20.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_S_BEZS801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		4 / 6 SER A 226
MET A 253
LEU A 189
LEU A 202
 None
 1.11A 5dzke-5efvA:
undetectable
5dzks-5efvA:
undetectable		 5dzke-5efvA:
16.56
5dzks-5efvA:
0.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		4 / 5 ILE A 224
PHE A 240
TYR A 187
THR A 211
 None
 1.26A 5z84N-5efvA:
undetectable
5z84W-5efvA:
undetectable		 5z84N-5efvA:
20.24
5z84W-5efvA:
6.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 5efv PHI ETA ORF 56-LIKE
PROTEIN
(Staphylococcus
virus
11) 		3 / 3 HIS A 186
ASN A 206
LEU A 229
 None
 0.87A 6f7lB-5efvA:
undetectable		 6f7lB-5efvA:
19.97