SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ehd'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XFS_A_J01A500_1
(ORF12)		 5ehd NUCLEOPHOSMIN
(Homo
sapiens) 		4 / 8 HIS A 110
LEU A  49
GLY A 107
ALA A  53
 None
 0.94A 2xfsA-5ehdA:
undetectable		 2xfsA-5ehdA:
14.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_A_ADNA439_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ehd NUCLEOPHOSMIN
(Homo
sapiens) 		5 / 10 LEU A  57
HIS A  58
GLN A  84
THR A  78
LEU A  49
 None
 1.42A 3h9uA-5ehdA:
undetectable		 3h9uA-5ehdA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H9U_D_ADND438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ehd NUCLEOPHOSMIN
(Homo
sapiens) 		5 / 10 LEU A  57
HIS A  58
GLN A  84
THR A  78
LEU A  49
 None
 1.47A 3h9uD-5ehdA:
undetectable		 3h9uD-5ehdA:
13.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UQ6_B_ADNB401_2
(ADENOSINE KINASE,
PUTATIVE)		 5ehd NUCLEOPHOSMIN
(Homo
sapiens) 		4 / 5 LEU A  44
GLY A 113
PHE A  31
ASN A  16
 None
 1.16A 3uq6B-5ehdA:
undetectable		 3uq6B-5ehdA:
16.67