SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ehk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1BDW_B_DVAB8_0
(GRAMICIDIN A)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		3 / 3 VAL A 976
VAL A 973
TRP A 984
 None
 0.61A 1bdwA-5ehkA:
undetectable
1bdwB-5ehkA:
undetectable		 1bdwA-5ehkA:
5.22
1bdwB-5ehkA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NB9_A_RBFA401_1
(HYPOTHETICAL PROTEIN
FLJ11149)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 9 THR A 686
ILE A 787
VAL A 508
LEU A 791
ILE A 387
 None
 1.33A 1nb9A-5ehkA:
undetectable		 1nb9A-5ehkA:
7.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_B_PODB700_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 12 VAL A 269
ALA A 277
LEU A 282
ALA A 251
VAL A 195
 None
 1.04A 1sa1A-5ehkA:
undetectable
1sa1B-5ehkA:
undetectable		 1sa1A-5ehkA:
17.29
1sa1B-5ehkA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SA1_D_PODD701_1
(TUBULIN ALPHA CHAIN
TUBULIN BETA CHAIN)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 12 VAL A 269
ALA A 277
LEU A 282
ALA A 251
VAL A 195
 None
 1.05A 1sa1C-5ehkA:
undetectable
1sa1D-5ehkA:
undetectable		 1sa1C-5ehkA:
17.29
1sa1D-5ehkA:
17.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SQ5_D_PAUD6004_0
(PANTOTHENATE KINASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 10 VAL A 182
LEU A 290
HIS A 298
LEU A 179
ILE A 283
 None
 1.50A 1sq5D-5ehkA:
undetectable		 1sq5D-5ehkA:
14.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TUV_A_VK3A4558_1
(PROTEIN YGIN)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 7 GLU A 280
HIS A 183
LEU A 179
ILE A 574
 None
 0.88A 1tuvA-5ehkA:
6.6		 1tuvA-5ehkA:
6.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WOP_A_FFOA2888_0
(AMINOMETHYLTRANSFERA
SE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 10 LEU A 737
GLU A 753
LEU A 749
ILE A 135
LEU A 128
 None
 1.13A 1wopA-5ehkA:
1.3		 1wopA-5ehkA:
15.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XLX_A_CIOA101_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4B)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 12 HIS A 183
LEU A 212
ILE A 283
SER A 595
GLN A 201
 None
 1.38A 1xlxA-5ehkA:
undetectable		 1xlxA-5ehkA:
16.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAT_A_FK5A108_1
(FK506 BINDING
PROTEIN)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 11 ASP A1034
PHE A 947
VAL A 954
ILE A 957
LEU A1030
 None
 1.34A 1yatA-5ehkA:
undetectable		 1yatA-5ehkA:
5.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 8 ARG A1111
GLY A1103
PRO A1024
GLY A1026
 None
 0.84A 2y6rB-5ehkA:
undetectable		 2y6rB-5ehkA:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3APX_A_Z80A190_1
(ALPHA-1-ACID
GLYCOPROTEIN 2)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 12 GLU A 482
LEU A 397
ARG A 396
GLU A 392
ALA A 493
 None
 1.38A 3apxA-5ehkA:
undetectable		 3apxA-5ehkA:
9.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GAL_A_1GNA998_1
(GALECTIN-7)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 6 HIS A 803
ASN A 617
ARG A 620
GLU A 631
 None
 1.42A 3galA-5ehkA:
undetectable		 3galA-5ehkA:
8.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3H0A_A_9RAA500_1
(RETINOIC ACID
RECEPTOR RXR-ALPHA)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		6 / 12 ALA A 934
LEU A 941
LEU A1044
ALA A1043
VAL A1097
LEU A 951
 None
 1.47A 3h0aA-5ehkA:
undetectable		 3h0aA-5ehkA:
12.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3I5U_B_SAMB401_1
(O-METHYLTRANSFERASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		3 / 3 ASP A 931
PHE A 857
SER A 937
 None
 0.93A 3i5uB-5ehkA:
2.2		 3i5uB-5ehkA:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_C_TFPC202_1
(PROTEIN S100-A4)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 11 PHE A 947
LEU A1021
ILE A 957
GLU A 953
ASP A 952
 None
 1.30A 3ko0A-5ehkA:
undetectable
3ko0B-5ehkA:
undetectable
3ko0C-5ehkA:
undetectable
3ko0D-5ehkA:
undetectable		 3ko0A-5ehkA:
6.15
3ko0B-5ehkA:
6.15
3ko0C-5ehkA:
6.15
3ko0D-5ehkA:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_F_TFPF202_1
(PROTEIN S100-A4)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 11 GLU A 953
ASP A 952
LEU A1021
ILE A 957
PHE A 947
 None
 1.37A 3ko0E-5ehkA:
undetectable
3ko0F-5ehkA:
0.3
3ko0G-5ehkA:
undetectable
3ko0H-5ehkA:
undetectable		 3ko0E-5ehkA:
6.15
3ko0F-5ehkA:
6.15
3ko0G-5ehkA:
6.15
3ko0H-5ehkA:
6.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MTE_A_SAMA220_0
(16S RRNA METHYLASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 12 GLY A1103
PRO A1015
ALA A1016
LEU A1109
SER A 999
 None
 1.20A 3mteA-5ehkA:
undetectable		 3mteA-5ehkA:
10.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NS1_C_PM6C1_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 6 ARG A1047
THR A1082
ALA A 933
ALA A 934
 None
 1.23A 3ns1C-5ehkA:
undetectable		 3ns1C-5ehkA:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 8 ASP A 668
GLY A 670
PRO A 666
GLU A 665
 None
 0.56A 3s3mA-5ehkA:
undetectable		 3s3mA-5ehkA:
15.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 8 ASP A 668
GLY A 670
PRO A 666
GLU A 665
 None
 0.57A 3s3nA-5ehkA:
undetectable		 3s3nA-5ehkA:
15.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TM4_A_SAMA401_0
(TRNA (GUANINE
N2-)-METHYLTRANSFERA
SE TRM14)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 12 LEU A 328
MET A 175
ALA A 581
PRO A 295
LEU A 290
 None
 1.34A 3tm4A-5ehkA:
4.5		 3tm4A-5ehkA:
14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 8 GLN A 556
HIS A 533
GLY A 535
GLY A 292
 None
 0.91A 3v3nB-5ehkA:
undetectable		 3v3nB-5ehkA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 8 GLN A 556
HIS A 533
GLY A 535
GLY A 292
 None
 0.88A 3v3nC-5ehkA:
undetectable		 3v3nC-5ehkA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_J_CHDJ101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 6 ILE A 373
LEU A 375
ARG A 136
THR A 139
 None
 1.18A 3wg7A-5ehkA:
1.8
3wg7J-5ehkA:
undetectable		 3wg7A-5ehkA:
17.65
3wg7J-5ehkA:
3.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A7A_B_RGZB601_1
(AMINE OXIDASE
[FLAVIN-CONTAINING]
B)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 12 PRO A 634
LEU A 623
LEU A 426
LEU A 609
ILE A 607
 None
 1.12A 4a7aB-5ehkA:
undetectable		 4a7aB-5ehkA:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A97_I_ZPCI1318_2
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 6 GLU A 606
ILE A 607
HIS A 533
VAL A 640
 None
 1.10A 4a97I-5ehkA:
undetectable		 4a97I-5ehkA:
12.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTR_A_IBPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 8 VAL A 360
TRP A 177
LEU A 300
LEU A 296
 None
 0.92A 4jtrA-5ehkA:
undetectable		 4jtrA-5ehkA:
14.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB2_A_DM5A602_1
(SERUM ALBUMIN)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 7 PRO A1024
VAL A1105
ALA A1101
TYR A 949
 None
 0.99A 4lb2A-5ehkA:
undetectable		 4lb2A-5ehkA:
20.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LVC_B_ADNB501_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE
(SAHASE))		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 5 THR A 484
THR A 686
LEU A 394
LEU A 397
 None
 1.10A 4lvcB-5ehkA:
undetectable		 4lvcB-5ehkA:
18.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 12 VAL A1105
LEU A1007
GLY A1103
ARG A1102
THR A1001
 None
 1.27A 4o5fA-5ehkA:
undetectable
4o5fB-5ehkA:
undetectable		 4o5fA-5ehkA:
14.70
4o5fB-5ehkA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 12 VAL A1105
LEU A1007
GLY A1103
ARG A1102
THR A1001
 None
 1.25A 4o5fA-5ehkA:
undetectable
4o5fB-5ehkA:
undetectable		 4o5fA-5ehkA:
14.70
4o5fB-5ehkA:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ODO_A_FK5A205_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
SLYD)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 4 THR A 385
ARG A 685
GLU A 386
VAL A 382
 None
 1.41A 4odoC-5ehkA:
undetectable		 4odoC-5ehkA:
9.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OLT_B_GCSB304_1
(CHITOSANASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 5 TYR A 822
ILE A 858
HIS A1080
TYR A 915
 None
 1.39A 4oltB-5ehkA:
undetectable		 4oltB-5ehkA:
13.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QWP_A_GCSA303_1
(CHITOSANASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 6 TYR A 822
ILE A 858
HIS A1080
TYR A 915
 None
 1.35A 4qwpA-5ehkA:
1.5		 4qwpA-5ehkA:
13.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YIA_B_IMNB401_2
(THYROXINE-BINDING
GLOBULIN)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		3 / 3 LEU A1086
ARG A1093
ARG A 859
 None
 0.94A 4yiaB-5ehkA:
undetectable		 4yiaB-5ehkA:
3.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_A_ADNA502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 5 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.26A 5axaA-5ehkA:
undetectable		 5axaA-5ehkA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AXA_C_ADNC502_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 5 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.25A 5axaC-5ehkA:
undetectable		 5axaC-5ehkA:
17.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 12 VAL A1105
LEU A1007
GLY A1103
ARG A1102
THR A1001
 None
 1.27A 5b8hA-5ehkA:
undetectable
5b8hB-5ehkA:
undetectable		 5b8hA-5ehkA:
16.22
5b8hB-5ehkA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 12 VAL A1105
LEU A1007
GLY A1103
ARG A1102
THR A1001
 None
 1.28A 5b8hA-5ehkA:
undetectable
5b8hB-5ehkA:
undetectable		 5b8hA-5ehkA:
16.22
5b8hB-5ehkA:
16.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 11 ALA A 306
ALA A 316
LEU A 191
LEU A 286
VAL A 325
 None
 1.31A 5eb5A-5ehkA:
undetectable		 5eb5A-5ehkA:
19.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 12 GLU A 659
VAL A 614
GLY A 591
LEU A 561
HIS A 562
 None
 1.21A 5esgA-5ehkA:
undetectable		 5esgA-5ehkA:
18.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 5 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.23A 5hm8A-5ehkA:
undetectable		 5hm8A-5ehkA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 5 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.23A 5hm8B-5ehkA:
undetectable		 5hm8B-5ehkA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 5 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.24A 5hm8C-5ehkA:
undetectable		 5hm8C-5ehkA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 5 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.23A 5hm8D-5ehkA:
undetectable		 5hm8D-5ehkA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 5 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.24A 5hm8E-5ehkA:
undetectable		 5hm8E-5ehkA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 5 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.24A 5hm8F-5ehkA:
undetectable		 5hm8F-5ehkA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_G_ADNG501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 5 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.23A 5hm8G-5ehkA:
2.9		 5hm8G-5ehkA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 5 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.23A 5hm8H-5ehkA:
undetectable		 5hm8H-5ehkA:
17.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HUA_A_FK5A201_1
(FK506-BINDING
PROTEIN 1)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 11 ASP A1034
PHE A 947
VAL A 954
ILE A 957
LEU A1030
 None
 1.31A 5huaA-5ehkA:
undetectable		 5huaA-5ehkA:
6.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKR_B_ID8B602_2
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		3 / 3 SER A 231
LEU A 272
MET A 276
 None
 0.80A 5ikrB-5ehkA:
undetectable		 5ikrB-5ehkA:
17.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M0O_A_EPAA502_1
(TERMINAL
OLEFIN-FORMING FATTY
ACID DECARBOXYLASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 10 LEU A 612
ILE A 607
PRO A 634
ALA A 569
VAL A 596
 None
 1.12A 5m0oA-5ehkA:
undetectable		 5m0oA-5ehkA:
15.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 4 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.24A 5v96A-5ehkA:
undetectable		 5v96A-5ehkA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 4 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.24A 5v96B-5ehkA:
undetectable		 5v96B-5ehkA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 4 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.20A 5v96C-5ehkA:
undetectable		 5v96C-5ehkA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 4 GLU A 482
THR A 484
THR A 686
LEU A 394
 None
 1.20A 5v96D-5ehkA:
undetectable		 5v96D-5ehkA:
17.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_G_CVIG301_0
(REGULATORY PROTEIN
TETR)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 12 ALA A  86
GLU A  97
LEU A 103
ARG A 122
VAL A 110
 None
 1.28A 5vlmG-5ehkA:
undetectable		 5vlmG-5ehkA:
10.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VYH_A_FOLA409_0
(S PROTEIN)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		5 / 10 PRO A 634
GLY A 629
THR A 628
ILE A 804
ALA A 566
 None
 1.27A 5vyhA-5ehkA:
undetectable		 5vyhA-5ehkA:
14.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6A4I_B_TRPB403_0
(TRYPTOPHAN
2,3-DIOXYGENASE)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 7 ARG A 736
THR A  17
PRO A  18
PRO A 781
 None
 1.31A 6a4iB-5ehkA:
undetectable		 6a4iB-5ehkA:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_W_CHDW101_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5ehk LANTIBIOTIC
DEHYDRATASE
(Microbispora
corallina) 		4 / 6 ILE A 373
LEU A 375
ARG A 136
THR A 139
 None
 1.12A 6nmfN-5ehkA:
undetectable
6nmfW-5ehkA:
undetectable		 6nmfN-5ehkA:
17.65
6nmfW-5ehkA:
3.87