SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eid'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UCB_A_017A201_1
(PROTEASE)		 5eid ANKYRIN REPEAT
DOMAIN-CONTAINING
PROTEIN 2
(Arabidopsis
thaliana) 		5 / 12 LEU A 335
ALA A 292
ASN A 327
GLY A 260
VAL A 332
 None
 0.93A 3ucbA-5eidA:
undetectable		 3ucbA-5eidA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_B_SALB1345_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5eid ANKYRIN REPEAT
DOMAIN-CONTAINING
PROTEIN 2
(Arabidopsis
thaliana) 		4 / 8 LEU A 288
VAL A 332
LEU A 335
ALA A 340
 None
 0.88A 3uniB-5eidA:
undetectable		 3uniB-5eidA:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_2
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5eid ANKYRIN REPEAT
DOMAIN-CONTAINING
PROTEIN 2
(Arabidopsis
thaliana) 		4 / 4 LEU A 335
TYR A 294
PRO A 320
ILE A 321
 None
 1.41A 5esgA-5eidA:
undetectable		 5esgA-5eidA:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MAF_A_XINA403_2
(MATERNAL EMBRYONIC
LEUCINE ZIPPER
KINASE)		 5eid ANKYRIN REPEAT
DOMAIN-CONTAINING
PROTEIN 2
(Arabidopsis
thaliana) 		4 / 5 LEU A 234
CYH A 299
LEU A 302
ASP A 272
 None
 1.42A 5mafA-5eidA:
undetectable		 5mafA-5eidA:
29.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 5eid ANKYRIN REPEAT
DOMAIN-CONTAINING
PROTEIN 2
(Arabidopsis
thaliana) 		4 / 6 LEU A 336
ALA A 340
THR A 286
ASN A 314
 None
 0.93A 6f88A-5eidA:
undetectable		 6f88A-5eidA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 5eid ANKYRIN REPEAT
DOMAIN-CONTAINING
PROTEIN 2
(Arabidopsis
thaliana) 		4 / 6 LEU A 342
ALA A 340
THR A 286
ASN A 278
 None
 1.01A 6f88A-5eidA:
undetectable		 6f88A-5eidA:
20.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_B_STRB502_1
(CYTOCHROME P450
CYP260A1)		 5eid ANKYRIN REPEAT
DOMAIN-CONTAINING
PROTEIN 2
(Arabidopsis
thaliana) 		4 / 6 LEU A 336
ALA A 340
THR A 286
ASN A 314
 None
 0.98A 6f88B-5eidA:
undetectable		 6f88B-5eidA:
20.14