SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eik'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 5eik UNCHARACTERIZED
PROTEIN Y57A10A.28
(Caenorhabditis
elegans) 		4 / 6 PHE A 229
ALA A 197
GLY A 164
VAL A 161
 None
 0.76A 4dubA-5eikA:
1.5		 4dubA-5eikA:
21.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_A_FLPA401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5eik UNCHARACTERIZED
PROTEIN Y57A10A.28
(Caenorhabditis
elegans) 		5 / 10 VAL A  22
TYR A  21
VAL A 226
ILE A 230
LEU A 129
 None
DMU  A 310 ( 2.9A)
None
None
None
 1.49A 4jtqA-5eikA:
undetectable		 4jtqA-5eikA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JTQ_B_FLPB401_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C2)		 5eik UNCHARACTERIZED
PROTEIN Y57A10A.28
(Caenorhabditis
elegans) 		5 / 9 VAL A  22
TYR A  21
VAL A 226
ILE A 230
LEU A 129
 None
DMU  A 310 ( 2.9A)
None
None
None
 1.41A 4jtqB-5eikA:
undetectable		 4jtqB-5eikA:
22.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5eik UNCHARACTERIZED
PROTEIN Y57A10A.28
(Caenorhabditis
elegans) 		4 / 8 PHE A 229
TYR A 222
GLY A 160
ILE A 157
 None
None
None
DMU  A 312 ( 4.7A)
 0.96A 4qoiA-5eikA:
undetectable
4qoiB-5eikA:
undetectable		 4qoiA-5eikA:
23.55
4qoiB-5eikA:
23.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CI6_A_NBOA606_1
(SERUM ALBUMIN)		 5eik UNCHARACTERIZED
PROTEIN Y57A10A.28
(Caenorhabditis
elegans) 		5 / 12 ARG A 147
VAL A 159
GLY A 141
SER A  77
LEU A  81
 None
 1.44A 6ci6A-5eikA:
1.8		 6ci6A-5eikA:
18.53