SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eip'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FM6_D_BRLD503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5eip YTH
DOMAIN-CONTAINING
PROTEIN MMI1
(Schizosaccharomy
ces
pombe) 		4 / 4 ILE A 448
LEU A 356
VAL A 396
ILE A 394
 None
 0.87A 1fm6D-5eipA:
undetectable		 1fm6D-5eipA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1KIJ_B_NOVB444_2
(DNA GYRASE SUBUNIT B)		 5eip YTH
DOMAIN-CONTAINING
PROTEIN MMI1
(Schizosaccharomy
ces
pombe) 		3 / 3 ASP A 460
PHE A 393
VAL A 374
 None
 0.75A 1kijB-5eipA:
undetectable		 1kijB-5eipA:
16.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RTS_A_D16A309_1
(THYMIDYLATE SYNTHASE)		 5eip YTH
DOMAIN-CONTAINING
PROTEIN MMI1
(Schizosaccharomy
ces
pombe) 		4 / 8 PHE A 393
ILE A 432
GLY A 405
PHE A 395
 None
 0.81A 1rtsA-5eipA:
undetectable		 1rtsA-5eipA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H3A_B_D16B401_1
(ORF70)		 5eip YTH
DOMAIN-CONTAINING
PROTEIN MMI1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE A 393
ILE A 432
GLY A 405
PHE A 395
 None
 0.74A 5h3aB-5eipA:
undetectable		 5h3aB-5eipA:
17.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_A_SALA301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5eip YTH
DOMAIN-CONTAINING
PROTEIN MMI1
(Schizosaccharomy
ces
pombe) 		4 / 5 ALA A 407
VAL A 409
PHE A 395
ILE A 382
 None
 0.93A 5of1A-5eipA:
undetectable		 5of1A-5eipA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OF1_B_SALB301_1
(SPORE
COAT-ASSOCIATED
PROTEIN N)		 5eip YTH
DOMAIN-CONTAINING
PROTEIN MMI1
(Schizosaccharomy
ces
pombe) 		4 / 5 ALA A 407
VAL A 409
PHE A 395
ILE A 382
 None
 0.91A 5of1B-5eipA:
undetectable		 5of1B-5eipA:
19.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_C_D16C402_1
(THYMIDYLATE SYNTHASE)		 5eip YTH
DOMAIN-CONTAINING
PROTEIN MMI1
(Schizosaccharomy
ces
pombe) 		4 / 7 PHE A 393
ILE A 432
GLY A 405
PHE A 395
 None
 0.81A 5x5qC-5eipA:
undetectable		 5x5qC-5eipA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_D_D16D402_1
(THYMIDYLATE SYNTHASE)		 5eip YTH
DOMAIN-CONTAINING
PROTEIN MMI1
(Schizosaccharomy
ces
pombe) 		4 / 8 PHE A 393
ILE A 432
GLY A 405
PHE A 395
 None
 0.82A 5x5qD-5eipA:
undetectable		 5x5qD-5eipA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_F_D16F402_1
(THYMIDYLATE SYNTHASE)		 5eip YTH
DOMAIN-CONTAINING
PROTEIN MMI1
(Schizosaccharomy
ces
pombe) 		4 / 8 PHE A 393
ILE A 432
GLY A 405
PHE A 395
 None
 0.82A 5x5qF-5eipA:
undetectable		 5x5qF-5eipA:
18.88