SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ej0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WG8_B_SAMB3141_1
(PREDICTED
S-ADENOSYLMETHIONINE
-DEPENDENT
METHYLTRANSFERASE)		 5ej0 ENVELOPE PROTEIN H3
(Vaccinia
virus) 		3 / 3 HIS A 144
ASP A 149
ASN A 197
 None
MOH  A 720 (-2.8A)
None
 0.64A 1wg8B-5ej0A:
undetectable		 1wg8B-5ej0A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CZH_A_D2VA602_2
(CYTOCHROME P450 2R1)		 5ej0 ENVELOPE PROTEIN H3
(Vaccinia
virus) 		3 / 3 LEU A 208
GLU A 201
ILE A 198
 None
 0.55A 3czhA-5ej0A:
undetectable		 3czhA-5ej0A:
19.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J6P_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5ej0 ENVELOPE PROTEIN H3
(Vaccinia
virus) 		5 / 12 VAL A  11
HIS A 101
PHE A 110
THR A 194
ARG A 227
 None
None
None
PG0  A 705 (-3.1A)
EOH  A 718 (-4.1A)
 1.32A 3j6pB-5ej0A:
undetectable		 3j6pB-5ej0A:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TMZ_A_06XA503_1
(CYTOCHROME P450 2B4)		 5ej0 ENVELOPE PROTEIN H3
(Vaccinia
virus) 		5 / 11 ILE A 130
ILE A 133
GLU A  27
VAL A  10
VAL A   8
 None
 1.10A 3tmzA-5ej0A:
undetectable		 3tmzA-5ej0A:
19.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CK2_C_IPHC101_0
(INSULIN A CHAIN
INSULIN B CHAIN)		 5ej0 ENVELOPE PROTEIN H3
(Vaccinia
virus) 		4 / 4 ILE A 189
LEU A 166
HIS A 144
ALA A 142
 None
 1.00A 6ck2C-5ej0A:
undetectable
6ck2D-5ej0A:
undetectable		 6ck2C-5ej0A:
7.65
6ck2D-5ej0A:
8.12