SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ej1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMC_A_SAMA105_0
(MET REPRESSOR)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 ALA B 365
GLY B 363
ARG B 334
LEU B 368
PRO B 369
 None
 1.16A 1cmcA-5ej1B:
undetectable
1cmcB-5ej1B:
undetectable		 1cmcA-5ej1B:
10.42
1cmcB-5ej1B:
10.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FE2_A_LAXA700_1
(PROSTAGLANDIN
ENDOPEROXIDE H
SYNTHASE-1)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 VAL B 448
VAL B 440
VAL B 376
VAL B 378
LEU B 446
 None
 1.23A 1fe2A-5ej1B:
undetectable		 1fe2A-5ej1B:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 9 VAL B 278
GLY B 190
ALA B 198
THR B  89
ILE B 189
 None
 1.27A 1gtnL-5ej1B:
undetectable
1gtnM-5ej1B:
undetectable		 1gtnL-5ej1B:
8.18
1gtnM-5ej1B:
8.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXW_B_RITB301_2
(HIV-1 PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 11 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.93A 1hxwB-5ej1A:
undetectable		 1hxwB-5ej1A:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_A_SAMA2200_0
(PROTEIN (METHIONINE
REPRESSOR))		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 ALA B 365
GLY B 363
ARG B 334
LEU B 368
PRO B 369
 None
 1.09A 1mj2A-5ej1B:
undetectable
1mj2B-5ej1B:
undetectable		 1mj2A-5ej1B:
10.26
1mj2B-5ej1B:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJ2_C_SAMC2199_0
(PROTEIN (METHIONINE
REPRESSOR))		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 ALA B 365
GLY B 363
ARG B 334
LEU B 368
PRO B 369
 None
 1.07A 1mj2C-5ej1B:
undetectable
1mj2D-5ej1B:
undetectable		 1mj2C-5ej1B:
10.26
1mj2D-5ej1B:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 ALA B 365
GLY B 363
ARG B 334
LEU B 368
PRO B 369
 None
 1.11A 1mjoC-5ej1B:
undetectable
1mjoD-5ej1B:
undetectable		 1mjoC-5ej1B:
10.26
1mjoD-5ej1B:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_B_SAMB200_0
(METHIONINE REPRESSOR)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 11 HIS A 224
PHE A 335
GLY A 337
ARG A 326
LEU A 234
 None
 1.25A 1mjqA-5ej1A:
undetectable
1mjqB-5ej1A:
undetectable		 1mjqA-5ej1A:
9.13
1mjqB-5ej1A:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 ARG B 334
LEU B 368
PRO B 369
ALA B 365
GLY B 363
 None
 1.11A 1mjqC-5ej1B:
undetectable
1mjqD-5ej1B:
undetectable		 1mjqC-5ej1B:
10.26
1mjqD-5ej1B:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_D_SAMD200_0
(METHIONINE REPRESSOR)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 ALA B 365
GLY B 363
ARG B 334
LEU B 368
PRO B 369
 None
 1.09A 1mjqC-5ej1B:
undetectable
1mjqD-5ej1B:
undetectable		 1mjqC-5ej1B:
10.26
1mjqD-5ej1B:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_H_SAMH200_0
(METHIONINE REPRESSOR)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 HIS A 224
PHE A 335
GLY A 337
ARG A 326
LEU A 234
 None
 1.25A 1mjqG-5ej1A:
undetectable
1mjqH-5ej1A:
undetectable		 1mjqG-5ej1A:
9.13
1mjqH-5ej1A:
9.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 11 ARG B 334
LEU B 368
PRO B 369
ALA B 365
GLY B 363
 None
 1.10A 1mjqI-5ej1B:
undetectable
1mjqJ-5ej1B:
undetectable		 1mjqI-5ej1B:
10.26
1mjqJ-5ej1B:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_J_SAMJ200_0
(METHIONINE REPRESSOR)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 ALA B 365
GLY B 363
ARG B 334
LEU B 368
PRO B 369
 None
 1.08A 1mjqI-5ej1B:
undetectable
1mjqJ-5ej1B:
undetectable		 1mjqI-5ej1B:
10.26
1mjqJ-5ej1B:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1O86_A_LPRA702_2
(ANGIOTENSIN
CONVERTING ENZYME)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 4 SER A 611
VAL A 607
PHE A 690
VAL A 158
 C2E  A 919 (-3.5A)
None
None
None
 1.21A 1o86A-5ej1A:
3.9		 1o86A-5ej1A:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_ACTA860_0
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		4 / 5 GLY A  43
ILE A  45
VAL B 585
SER A  48
 None
 1.14A 1rs7A-5ej1A:
undetectable		 1rs7A-5ej1A:
19.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 6 ARG A 705
ILE A 707
GLY A 712
ALA A 714
 None
None
None
3PE  A 923 ( 4.4A)
 0.91A 1wmqA-5ej1A:
undetectable		 1wmqA-5ej1A:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WMQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 6 ARG A 705
ILE A 707
GLY A 712
ALA A 714
 None
None
None
3PE  A 923 ( 4.4A)
 0.92A 1wmqB-5ej1A:
undetectable		 1wmqB-5ej1A:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 6 ARG A 705
ILE A 707
GLY A 712
ALA A 714
 None
None
None
3PE  A 923 ( 4.4A)
 0.91A 1wpuA-5ej1A:
undetectable		 1wpuA-5ej1A:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WPU_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 6 ARG A 705
ILE A 707
GLY A 712
ALA A 714
 None
None
None
3PE  A 923 ( 4.4A)
 0.91A 1wpuB-5ej1A:
2.5		 1wpuB-5ej1A:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_A_HISA2001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 6 ARG A 705
ILE A 707
GLY A 712
ALA A 714
 None
None
None
3PE  A 923 ( 4.4A)
 0.91A 1wrqA-5ej1A:
undetectable		 1wrqA-5ej1A:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRQ_B_HISB1001_0
(HUT OPERON POSITIVE
REGULATORY PROTEIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 6 ARG A 705
ILE A 707
GLY A 712
ALA A 714
 None
None
None
3PE  A 923 ( 4.4A)
 0.93A 1wrqB-5ej1A:
undetectable		 1wrqB-5ej1A:
12.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HRC_B_CHDB1604_0
(FERROCHELATASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 4 LEU A 139
PRO A 136
LEU A 134
ARG A 258
 None
 1.41A 2hrcB-5ej1A:
2.9		 2hrcB-5ej1A:
19.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_1
(PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.81A 2ieoA-5ej1A:
undetectable		 2ieoA-5ej1A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_3
(PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 GLY A 676
GLY A 655
ILE A 672
VAL A 685
VAL A 681
 None
None
C2E  A 919 (-3.5A)
None
None
 0.89A 2nnkB-5ej1A:
undetectable		 2nnkB-5ej1A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_2
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		3 / 3 ARG A 210
GLU A 211
GLN A 206
 None
 1.06A 2p16A-5ej1A:
1.0		 2p16A-5ej1A:
14.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 9 LEU B 234
LEU B 230
ALA B 204
ALA B 256
PHE B 196
 None
 1.19A 2vcvH-5ej1B:
undetectable		 2vcvH-5ej1B:
14.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 TYR A 479
ARG A 471
GLN A 285
ARG A 715
 None
BGC  A 915 ( 2.8A)
None
None
 1.45A 2vxaA-5ej1A:
undetectable
2vxaC-5ej1A:
undetectable
2vxaE-5ej1A:
undetectable		 2vxaA-5ej1A:
10.05
2vxaC-5ej1A:
10.05
2vxaE-5ej1A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 GLN A 285
TYR A 479
ARG A 471
ARG A 715
 None
None
BGC  A 915 ( 2.8A)
None
 1.42A 2vxaA-5ej1A:
undetectable
2vxaB-5ej1A:
undetectable
2vxaK-5ej1A:
undetectable		 2vxaA-5ej1A:
10.05
2vxaB-5ej1A:
10.05
2vxaK-5ej1A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 GLN A 285
TYR A 479
ARG A 471
ARG A 715
 None
None
BGC  A 915 ( 2.8A)
None
 1.42A 2vxaB-5ej1A:
undetectable
2vxaC-5ej1A:
undetectable
2vxaG-5ej1A:
undetectable		 2vxaB-5ej1A:
10.05
2vxaC-5ej1A:
10.05
2vxaG-5ej1A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_D_RBFD200_1
(DODECIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 TYR A 479
ARG A 471
GLN A 285
ARG A 715
 None
BGC  A 915 ( 2.8A)
None
None
 1.42A 2vxaD-5ej1A:
undetectable
2vxaF-5ej1A:
undetectable
2vxaI-5ej1A:
undetectable		 2vxaD-5ej1A:
10.05
2vxaF-5ej1A:
10.05
2vxaI-5ej1A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 GLN A 285
TYR A 479
ARG A 471
ARG A 715
 None
None
BGC  A 915 ( 2.8A)
None
 1.44A 2vxaD-5ej1A:
undetectable
2vxaE-5ej1A:
undetectable
2vxaL-5ej1A:
undetectable		 2vxaD-5ej1A:
10.05
2vxaE-5ej1A:
10.05
2vxaL-5ej1A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_G_RBFG200_1
(DODECIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 ARG A 715
TYR A 479
ARG A 471
GLN A 285
 None
None
BGC  A 915 ( 2.8A)
None
 1.40A 2vxaF-5ej1A:
undetectable
2vxaG-5ej1A:
undetectable
2vxaI-5ej1A:
undetectable		 2vxaF-5ej1A:
10.05
2vxaG-5ej1A:
10.05
2vxaI-5ej1A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_H_RBFH200_1
(DODECIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 ARG A 715
GLN A 285
TYR A 479
ARG A 471
 None
None
None
BGC  A 915 ( 2.8A)
 1.44A 2vxaB-5ej1A:
undetectable
2vxaG-5ej1A:
undetectable
2vxaH-5ej1A:
undetectable		 2vxaB-5ej1A:
10.05
2vxaG-5ej1A:
10.05
2vxaH-5ej1A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_I_RBFI200_1
(DODECIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 GLN A 285
TYR A 479
ARG A 471
ARG A 715
 None
None
BGC  A 915 ( 2.8A)
None
 1.42A 2vxaH-5ej1A:
undetectable
2vxaI-5ej1A:
undetectable
2vxaJ-5ej1A:
undetectable		 2vxaH-5ej1A:
10.05
2vxaI-5ej1A:
10.05
2vxaJ-5ej1A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 ARG A 715
TYR A 479
ARG A 471
GLN A 285
 None
None
BGC  A 915 ( 2.8A)
None
 1.42A 2vxaD-5ej1A:
undetectable
2vxaJ-5ej1A:
undetectable
2vxaL-5ej1A:
undetectable		 2vxaD-5ej1A:
10.05
2vxaJ-5ej1A:
10.05
2vxaL-5ej1A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_K_RBFK200_1
(DODECIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 ARG A 715
GLN A 285
TYR A 479
ARG A 471
 None
None
None
BGC  A 915 ( 2.8A)
 1.42A 2vxaH-5ej1A:
undetectable
2vxaJ-5ej1A:
undetectable
2vxaK-5ej1A:
undetectable		 2vxaH-5ej1A:
10.05
2vxaJ-5ej1A:
10.05
2vxaK-5ej1A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_L_RBFL200_1
(DODECIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 ARG A 715
GLN A 285
TYR A 479
ARG A 471
 None
None
None
BGC  A 915 ( 2.8A)
 1.41A 2vxaA-5ej1A:
undetectable
2vxaK-5ej1A:
undetectable
2vxaL-5ej1A:
undetectable		 2vxaA-5ej1A:
10.05
2vxaK-5ej1A:
10.05
2vxaL-5ej1A:
10.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_B_IBPB1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 ILE A 491
LEU A 487
GLY A 386
GLN A 389
 None
 0.77A 2wd9B-5ej1A:
3.3		 2wd9B-5ej1A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_G_SVRG506_2
(PHOSPHOLIPASE A2)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 5 VAL A  51
VAL A  50
GLN A  42
ARG A  79
 None
 1.34A 3bjwB-5ej1A:
undetectable		 3bjwB-5ej1A:
9.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DDY_A_RBFA187_1
(LUMAZINE PROTEIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 VAL B  92
ILE B 189
ALA B 198
THR B 201
ASN B 149
 None
 1.23A 3ddyA-5ej1B:
undetectable		 3ddyA-5ej1B:
14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.83A 3ekpD-5ej1A:
undetectable		 3ekpD-5ej1A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_B_017B200_1
(PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 9 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.86A 3ektA-5ej1A:
undetectable		 3ektA-5ej1A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKT_D_017D200_1
(PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 11 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.88A 3ektC-5ej1A:
undetectable		 3ektC-5ej1A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKV_A_478A200_1
(PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.78A 3ekvA-5ej1A:
undetectable		 3ekvA-5ej1A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_B_URFB400_1
(URIDINE
PHOSPHORYLASE 1)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 GLY B 700
LEU B 698
LEU B 697
ILE A  45
 None
 0.90A 3nbqB-5ej1B:
undetectable		 3nbqB-5ej1B:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NBQ_C_URFC400_1
(URIDINE
PHOSPHORYLASE 1)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 GLY B 700
LEU B 698
LEU B 697
ILE A  45
 None
 0.88A 3nbqC-5ej1B:
undetectable		 3nbqC-5ej1B:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NU3_B_478B401_2
(PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 11 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.78A 3nu3B-5ej1A:
undetectable		 3nu3B-5ej1A:
8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 9 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.79A 3nujB-5ej1A:
undetectable		 3nujB-5ej1A:
8.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 9 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.75A 3nuoB-5ej1A:
undetectable		 3nuoB-5ej1A:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OEZ_A_STIA601_2
(PROTO-ONCOGENE
TYROSINE-PROTEIN
KINASE SRC)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 5 VAL B 378
ILE B 340
MET B 438
ARG B 402
 None
 1.15A 3oezA-5ej1B:
undetectable		 3oezA-5ej1B:
18.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_A_ADNA506_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		3 / 3 GLN A 273
THR A 274
LEU A 241
 None
 0.68A 3ondA-5ej1A:
undetectable		 3ondA-5ej1A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OND_B_ADNB507_2
(ADENOSYLHOMOCYSTEINA
SE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		3 / 3 GLN A 273
THR A 274
LEU A 241
 None
 0.67A 3ondB-5ej1A:
undetectable		 3ondB-5ej1A:
21.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OY4_B_017B200_2
(HIV-1 PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.95A 3oy4B-5ej1A:
undetectable		 3oy4B-5ej1A:
9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PYY_B_STIB4_2
(V-ABL ABELSON MURINE
LEUKEMIA VIRAL
ONCOGENE HOMOLOG 1
ISOFORM B VARIANT)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 5 VAL B 378
ILE B 340
MET B 438
ARG B 402
 None
 1.19A 3pyyB-5ej1B:
undetectable		 3pyyB-5ej1B:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TEH_B_DAHB786_1
(PHENYLALANYL-TRNA
SYNTHETASE BETA
CHAIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 7 PRO B 240
GLY B 207
GLU B 630
ALA B 204
 None
 1.00A 3tehB-5ej1B:
undetectable		 3tehB-5ej1B:
25.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UR0_B_SVRB516_1
(RNA-DEPENDENT RNA
POLYMERASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 7 PRO B 369
GLY B 371
ALA B 372
ALA B 165
 None
BGC  A 904 ( 4.1A)
None
None
 0.84A 3ur0B-5ej1B:
undetectable		 3ur0B-5ej1B:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UUD_A_ESTA600_1
(ESTROGEN RECEPTOR)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 11 LEU A 539
ALA A 537
LEU A 532
GLY A 557
LEU A 552
 None
 1.26A 3uudA-5ej1A:
undetectable		 3uudA-5ej1A:
16.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VM4_A_IZPA1_1
(FATTY ACID
ALPHA-HYDROXYLASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 5 LEU B  85
PHE B  86
PRO B  88
ALA B 198
 None
 1.46A 3vm4A-5ej1B:
undetectable		 3vm4A-5ej1B:
21.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WXO_A_NIZA804_1
(CATALASE-PEROXIDASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		3 / 3 ASN B 333
GLU B 168
ARG B 158
 None
 1.04A 3wxoA-5ej1B:
undetectable		 3wxoA-5ej1B:
23.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 GLY A 557
ALA A 559
ASN A 562
LEU A 552
VAL A 554
 None
None
None
None
BGC  A 909 ( 4.5A)
 1.22A 4azwA-5ej1A:
2.3		 4azwA-5ej1A:
20.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_A_ZMRA601_2
(NEURAMINIDASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		3 / 3 ARG B 334
ARG B 158
ILE B 421
 None
 0.77A 4b7qA-5ej1B:
undetectable		 4b7qA-5ej1B:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B7Q_C_ZMRC601_2
(NEURAMINIDASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		3 / 3 ARG B 334
ARG B 158
ILE B 421
 None
 0.75A 4b7qC-5ej1B:
undetectable		 4b7qC-5ej1B:
19.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_A_ACTA860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		4 / 5 GLY A  43
ILE A  45
VAL B 585
SER A  48
 None
 1.22A 4d33A-5ej1A:
undetectable		 4d33A-5ej1A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D33_B_ACTB860_0
(NITRIC OXIDE
SYNTHASE,
ENDOTHELIAL)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		4 / 5 GLY A  43
ILE A  45
VAL B 585
SER A  48
 None
 1.23A 4d33B-5ej1A:
undetectable		 4d33B-5ej1A:
20.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQB_B_017B101_2
(ASPARTYL PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.90A 4dqbB-5ej1A:
undetectable		 4dqbB-5ej1A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQC_A_017A101_2
(ASPARTYL PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 9 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.87A 4dqcB-5ej1A:
undetectable		 4dqcB-5ej1A:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQE_B_017B101_2
(ASPARTYL PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.93A 4dqeB-5ej1A:
undetectable		 4dqeB-5ej1A:
9.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DQH_B_017B101_2
(WILD-TYPE HIV-1
PROTEASE DIMER)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.94A 4dqhB-5ej1A:
undetectable		 4dqhB-5ej1A:
8.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_D_CLQD303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 6 GLY A 333
GLY A 334
GLU A 349
ILE A 350
 None
 0.97A 4fglD-5ej1A:
undetectable		 4fglD-5ej1A:
15.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVQ_A_ACTA904_0
(TYROSINE-PROTEIN
KINASE JAK2)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		3 / 3 PHE A 110
VAL A 422
GLU A 480
 None
None
BGC  A 914 ( 2.9A)
 0.54A 4fvqA-5ej1A:
1.4		 4fvqA-5ej1A:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A201_2
(PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.84A 4ll3B-5ej1A:
undetectable		 4ll3B-5ej1A:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LL3_A_017A202_1
(PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.85A 4ll3A-5ej1A:
undetectable		 4ll3A-5ej1A:
8.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NJT_B_017B101_2
(PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.94A 4njtB-5ej1A:
undetectable		 4njtB-5ej1A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_C_STRC601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 5 ILE A 672
ARG A 580
ASP A 609
VAL A 653
 C2E  A 919 (-3.5A)
C2E  A 920 ( 3.7A)
C2E  A 919 (-3.2A)
None
 0.91A 4nkxC-5ej1A:
undetectable		 4nkxC-5ej1A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4NKX_D_STRD601_2
(STEROID
17-ALPHA-HYDROXYLASE
/17,20 LYASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 5 ILE A 672
ARG A 580
ASP A 609
VAL A 653
 C2E  A 919 (-3.5A)
C2E  A 920 ( 3.7A)
C2E  A 919 (-3.2A)
None
 0.88A 4nkxD-5ej1A:
undetectable		 4nkxD-5ej1A:
21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4OAD_A_CLMA205_0
(GNAT SUPERFAMILY
ACETYLTRANSFERASE
PA4794)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 PHE B 125
GLU B 121
ALA B 143
GLY B 141
LEU B 140
 None
 1.32A 4oadA-5ej1B:
undetectable		 4oadA-5ej1B:
14.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 9 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.75A 4rvjB-5ej1A:
undetectable		 4rvjB-5ej1A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 9 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.76A 4rvjD-5ej1A:
undetectable		 4rvjD-5ej1A:
9.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 ALA B 551
ALA B 580
SER A  40
ALA B 555
 None
 0.80A 4twdF-5ej1B:
undetectable
4twdG-5ej1B:
undetectable
4twdH-5ej1B:
undetectable
4twdI-5ej1B:
undetectable
4twdJ-5ej1B:
undetectable		 4twdF-5ej1B:
17.88
4twdG-5ej1B:
17.88
4twdH-5ej1B:
17.88
4twdI-5ej1B:
17.88
4twdJ-5ej1B:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4TWD_F_377F402_1
(CYS-LOOP
LIGAND-GATED ION
CHANNEL)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 ALA B 580
SER A  40
ALA B 555
ALA B 551
 None
 0.81A 4twdF-5ej1B:
undetectable
4twdG-5ej1B:
undetectable
4twdH-5ej1B:
undetectable
4twdI-5ej1B:
undetectable
4twdJ-5ej1B:
undetectable		 4twdF-5ej1B:
17.88
4twdG-5ej1B:
17.88
4twdH-5ej1B:
17.88
4twdI-5ej1B:
17.88
4twdJ-5ej1B:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UYM_A_VORA590_1
(14-ALPHA STEROL
DEMETHYLASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 7 TYR A 479
ALA A 720
SER A 723
LEU A 290
 None
 1.05A 4uymA-5ej1A:
2.3		 4uymA-5ej1A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WG0_J_CHDJ103_0
(NUCLEAR RECEPTOR
COACTIVATOR 2)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 11 LEU B 621
LEU B 613
LEU B 463
ALA B 635
LEU B 638
 None
 1.12A 4wg0J-5ej1B:
undetectable
4wg0K-5ej1B:
undetectable
4wg0L-5ej1B:
undetectable		 4wg0J-5ej1B:
3.52
4wg0K-5ej1B:
3.52
4wg0L-5ej1B:
3.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WQ4_B_ACTB403_0
(TRNA N6-ADENOSINE
THREONYLCARBAMOYLTRA
NSFERASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		3 / 3 ARG A 327
ASP A 330
ARG A 326
 None
 0.66A 4wq4B-5ej1A:
undetectable		 4wq4B-5ej1A:
18.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XE5_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 6 PRO A 251
ILE A 144
VAL A 260
THR A 274
 None
 0.84A 4xe5A-5ej1A:
undetectable		 4xe5A-5ej1A:
21.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP4_A_COCA706_1
(DOPAMINE TRANSPORTER)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 11 PHE A 120
ALA B 705
VAL A 462
PHE A 115
GLY A 119
 None
None
None
BGC  A 913 ( 4.7A)
None
 1.19A 4xp4A-5ej1A:
undetectable		 4xp4A-5ej1A:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_A_RAUA400_1
(IMINE REDUCTASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 11 LEU A  26
TRP A  22
SER A  74
MET A  78
GLY A  30
 None
 1.39A 5g6sA-5ej1A:
3.5
5g6sG-5ej1A:
5.0		 5g6sA-5ej1A:
16.13
5g6sG-5ej1A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_B_RAUB400_1
(IMINE REDUCTASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 11 LEU A  26
TRP A  22
SER A  74
MET A  78
GLY A  30
 None
 1.39A 5g6sB-5ej1A:
5.0
5g6sC-5ej1A:
4.8		 5g6sB-5ej1A:
16.13
5g6sC-5ej1A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_C_RAUC400_1
(IMINE REDUCTASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 TRP A  22
SER A  74
MET A  78
GLY A  30
LEU A  26
 None
 1.39A 5g6sB-5ej1A:
5.0
5g6sC-5ej1A:
4.8		 5g6sB-5ej1A:
16.13
5g6sC-5ej1A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_D_RAUD400_1
(IMINE REDUCTASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU A  26
TRP A  22
SER A  74
MET A  78
GLY A  30
 None
 1.39A 5g6sD-5ej1A:
4.8
5g6sF-5ej1A:
5.1		 5g6sD-5ej1A:
16.13
5g6sF-5ej1A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_E_RAUE400_1
(IMINE REDUCTASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 11 LEU A  26
TRP A  22
SER A  74
MET A  78
GLY A  30
 None
 1.39A 5g6sE-5ej1A:
4.8
5g6sH-5ej1A:
5.0		 5g6sE-5ej1A:
16.13
5g6sH-5ej1A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_F_RAUF400_1
(IMINE REDUCTASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 TRP A  22
SER A  74
MET A  78
GLY A  30
LEU A  26
 None
 1.39A 5g6sD-5ej1A:
4.8
5g6sF-5ej1A:
5.1		 5g6sD-5ej1A:
16.13
5g6sF-5ej1A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G6S_G_RAUG400_1
(IMINE REDUCTASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 TRP A  22
SER A  74
MET A  78
GLY A  30
LEU A  26
 None
 1.39A 5g6sA-5ej1A:
3.5
5g6sG-5ej1A:
5.0		 5g6sA-5ej1A:
16.13
5g6sG-5ej1A:
16.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H5F_A_SAMA301_0
(PROTEIN ARGININE
N-METHYLTRANSFERASE
SFM1)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 GLY B 276
ASP B 275
ARG B 257
LEU B 184
ALA B 188
 None
 1.11A 5h5fA-5ej1B:
undetectable		 5h5fA-5ej1B:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 ILE B 197
PRO B 233
VAL B 268
ILE B 258
LEU B 282
 None
 1.13A 5ienB-5ej1B:
undetectable		 5ienB-5ej1B:
12.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGY_A_ERYA403_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 GLY A 308
ALA A 405
SER A 113
ILE A 114
PHE A 115
 None
None
None
BGC  A 914 ( 4.7A)
BGC  A 913 ( 4.7A)
 1.16A 5igyA-5ej1A:
0.0		 5igyA-5ej1A:
16.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KR0_A_478A101_2
(PROTEASE E35D-APV)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 9 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.83A 5kr0B-5ej1A:
undetectable		 5kr0B-5ej1A:
9.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCG_A_08YA602_2
(CYTOCHROME P450 3A4)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		3 / 3 ARG A 579
ARG A 584
ARG A 658
 C2E  A 919 ( 3.1A)
C2E  A 920 ( 3.3A)
C2E  A 919 ( 4.5A)
 0.95A 5vcgA-5ej1A:
undetectable		 5vcgA-5ej1A:
20.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA503_1
(CYTOCHROME P450 2C9)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 6 PHE A 598
PRO A 596
GLY A 599
ASN A 600
 None
 1.01A 5x24A-5ej1A:
undetectable		 5x24A-5ej1A:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_B_CHDB401_0
(BILE SALT HYDROLASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides;
Rhodobacter
sphaeroides) 		5 / 10 TYR A 451
LEU A  76
LEU A  44
ALA A  41
LEU B 697
 None
 1.23A 5y7pB-5ej1A:
undetectable		 5y7pB-5ej1A:
18.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_C_CHDC401_0
(BILE SALT HYDROLASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 LEU B 200
ILE B 270
ALA B 229
LEU B 226
 None
 0.80A 5y7pC-5ej1B:
undetectable		 5y7pC-5ej1B:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_G_CHDG401_0
(BILE SALT HYDROLASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 10 LEU B 200
ILE B 270
LEU B 298
ALA B 229
LEU B 226
 None
 1.07A 5y7pG-5ej1B:
undetectable		 5y7pG-5ej1B:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y9M_X_NIOX401_1
(CASEIN KINASE II
SUBUNIT ALPHA')		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 LEU A 145
VAL A 244
VAL A 242
ASP A 343
 None
None
None
BGC  A 918 ( 3.8A)
 0.71A 5y9mX-5ej1A:
undetectable		 5y9mX-5ej1A:
7.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B0I_B_TA1B502_1
(TUBULIN BETA CHAIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A  56
ALA A  72
SER A  74
GLY B 699
LEU B 698
 None
 1.00A 6b0iB-5ej1A:
undetectable		 6b0iB-5ej1A:
6.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_2
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 5 THR B 581
LEU A  76
VAL A  53
LEU B 702
 None
 0.87A 6bqgA-5ej1B:
undetectable		 6bqgA-5ej1B:
9.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BXN_B_SAMB901_0
(DIPHTHAMIDE
BIOSYNTHESIS ENZYME
DPH2)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 PHE A 317
LEU A 309
GLY A 314
GLN A 273
VAL A 323
 None
 1.27A 6bxnB-5ej1A:
2.3		 6bxnB-5ej1A:
17.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DH0_A_017A101_1
(PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 GLY A 676
GLY A 655
ILE A 672
VAL A 685
VAL A 681
 None
None
C2E  A 919 (-3.5A)
None
None
 0.86A 6dh0B-5ej1A:
undetectable		 6dh0B-5ej1A:
7.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DIF_B_TPVB201_1
(HIV-1 PROTEASE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		5 / 12 LEU A 688
GLY A 614
VAL A 681
GLY A 655
ILE A 637
 None
C2E  A 919 (-3.4A)
None
None
None
 0.88A 6difB-5ej1A:
undetectable		 6difB-5ej1A:
7.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DJZ_C_GMJC301_1
(SIGMA NON-OPIOID
INTRACELLULAR
RECEPTOR 1)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 6 LEU A 205
ASP A 248
GLN A 379
GLU A 151
 None
 1.38A 6djzC-5ej1A:
undetectable		 6djzC-5ej1A:
15.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_A_ADNA503_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		3 / 3 LEU A 402
GLN A 406
LYS A 394
 None
 0.97A 6exiB-5ej1A:
2.7		 6exiB-5ej1A:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EXI_B_ADNB503_0
(ADENOSYLHOMOCYSTEINA
SE)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		3 / 3 LEU A 402
GLN A 406
LYS A 394
 None
 0.94A 6exiA-5ej1A:
2.7		 6exiA-5ej1A:
8.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MDQ_A_TESA605_0
(SERUM ALBUMIN)		 5ej1 PUTATIVE CELLULOSE
SYNTHASE
(Rhodobacter
sphaeroides) 		4 / 8 GLY B 609
LEU B 625
GLY B 626
LEU B 527
 None
 0.76A 6mdqA-5ej1B:
undetectable		 6mdqA-5ej1B:
7.47