SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ejb'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MRQ_A_STRA501_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		5 / 11 LEU B  87
VAL B 269
ILE B 276
LEU B 207
LEU B 210
 None
 1.17A 1mrqA-5ejbB:
undetectable		 1mrqA-5ejbB:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX4_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		4 / 8 ILE B  59
PHE B 214
GLY B 236
GLY B 237
 None
 0.76A 2qx4A-5ejbB:
undetectable
2qx4B-5ejbB:
undetectable		 2qx4A-5ejbB:
18.15
2qx4B-5ejbB:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QX6_A_ML1A233_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		4 / 6 ILE B  59
PHE B 214
GLY B 236
GLY B 237
 None
 0.77A 2qx6A-5ejbB:
undetectable
2qx6B-5ejbB:
undetectable		 2qx6A-5ejbB:
18.15
2qx6B-5ejbB:
18.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3C6G_A_VD3A701_2
(CYTOCHROME P450 2R1)		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		3 / 3 MET B  76
VAL B  68
GLU B 196
 None
 0.60A 3c6gA-5ejbB:
undetectable		 3c6gA-5ejbB:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_B_DSFB319_1
(GLR4197 PROTEIN)		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		5 / 9 TYR B 275
ILE B 277
ILE B 276
ILE B  90
ILE B  94
 None
 1.09A 3p4wB-5ejbB:
undetectable		 3p4wB-5ejbB:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_D_DSFD319_1
(GLR4197 PROTEIN)		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		5 / 10 TYR B 275
ILE B 277
ILE B 276
ILE B  90
ILE B  94
 None
 1.10A 3p4wD-5ejbB:
undetectable		 3p4wD-5ejbB:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P4W_E_DSFE319_1
(GLR4197 PROTEIN)		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		5 / 10 TYR B 275
ILE B 277
ILE B 276
ILE B  90
ILE B  94
 None
 1.09A 3p4wE-5ejbB:
undetectable		 3p4wE-5ejbB:
22.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S53_A_017A201_2
(PROTEASE)		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		5 / 11 LEU B 172
ALA B 234
ILE B 276
ILE B  57
ILE B  59
 None
 0.82A 3s53B-5ejbB:
undetectable		 3s53B-5ejbB:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		3 / 3 GLN B 265
THR B 263
ASN B 224
 None
 0.86A 3v4tE-5ejbB:
undetectable		 3v4tE-5ejbB:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		5 / 12 LEU B 172
ILE B 276
ILE B 266
GLY B 264
ILE B  59
 None
 0.92A 4q1yB-5ejbB:
undetectable		 4q1yB-5ejbB:
13.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Y8W_C_STRC603_1
(CYTOCHROME P450
21-HYDROXYLASE)		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		5 / 12 LEU B 210
VAL B 269
ILE B 266
GLY B  85
LEU B 207
 None
 0.95A 4y8wC-5ejbB:
undetectable		 4y8wC-5ejbB:
22.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YVP_B_GBMB402_1
(ALDO-KETO REDUCTASE
FAMILY 1 MEMBER C1)		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		5 / 12 LEU B  87
VAL B 269
ILE B 276
LEU B 207
LEU B 210
 None
 1.28A 4yvpB-5ejbB:
undetectable		 4yvpB-5ejbB:
21.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5J_A_017A201_1
(PROTEASE)		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		5 / 12 LEU B 172
ALA B 234
ILE B 276
ILE B  57
ILE B  59
 None
 0.81A 5e5jA-5ejbB:
undetectable		 5e5jA-5ejbB:
11.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E5K_B_017B201_2
(HIV-1 PROTEASE)		 5ejb FUSION GLYCOPROTEIN
F0
(Hendra
henipavirus) 		5 / 12 LEU B 172
ALA B 234
ILE B 276
ILE B  57
ILE B  59
 None
 0.85A 5e5kB-5ejbB:
undetectable		 5e5kB-5ejbB:
11.61