SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ejh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1EKJ_G_ACTG3009_0
(BETA-CARBONIC
ANHYDRASE)		 5ejh NAD KINASE 1
(Listeria
monocytogenes) 		4 / 5 GLY A 151
LEU A 152
THR A 125
VAL A 135
 None
 1.13A 1ekjF-5ejhA:
undetectable
1ekjG-5ejhA:
undetectable		 1ekjF-5ejhA:
21.36
1ekjG-5ejhA:
21.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZGY_A_BRLA503_2
(PEROXISOME
PROLIFERATOR
ACTIVATED RECEPTOR
GAMMA)		 5ejh NAD KINASE 1
(Listeria
monocytogenes) 		4 / 5 ILE A  67
ILE A  62
ILE A   5
MET A  20
 None
 0.78A 1zgyA-5ejhA:
undetectable		 1zgyA-5ejhA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W98_B_P1ZB1359_1
(PROSTAGLANDIN
REDUCTASE 2)		 5ejh NAD KINASE 1
(Listeria
monocytogenes) 		4 / 6 GLU A 233
LYS A 215
PHE A 217
ILE A 219
 None
 1.36A 2w98B-5ejhA:
undetectable		 2w98B-5ejhA:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G10_A_ACTA301_0
(GLUTATHIONE
S-TRANSFERASE
HOMOLOG)		 5ejh NAD KINASE 1
(Listeria
monocytogenes) 		4 / 6 PRO A 174
ILE A 243
TYR A  75
PHE A 245
 CIT  A 302 ( 4.5A)
None
NAP  A 301 (-4.3A)
None
 1.13A 4g10A-5ejhA:
undetectable		 4g10A-5ejhA:
21.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RN6_B_15UB301_1
(THROMBIN HEAVY CHAIN)		 5ejh NAD KINASE 1
(Listeria
monocytogenes) 		6 / 12 TYR A 236
LEU A 209
LEU A 167
ALA A 185
GLY A 151
GLY A 149
 None
 1.48A 4rn6B-5ejhA:
undetectable		 4rn6B-5ejhA:
22.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DBY_A_ACTA610_0
(SERUM ALBUMIN)		 5ejh NAD KINASE 1
(Listeria
monocytogenes) 		3 / 3 TYR A  27
LYS A  92
LYS A  88
 None
 1.23A 5dbyA-5ejhA:
undetectable		 5dbyA-5ejhA:
17.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_B_8LXB501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5ejh NAD KINASE 1
(Listeria
monocytogenes) 		5 / 12 LEU A  16
ILE A  67
ILE A  62
ILE A   5
MET A  20
 None
 1.12A 5y2tB-5ejhA:
undetectable		 5y2tB-5ejhA:
undetectable