SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ejk'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3L2V_A_RLTA397_1
(INTEGRASE)		 5ejk GAG-PRO-POL
POLYPROTEIN
(Rous
sarcoma
virus) 		4 / 7 ASP A  64
ASP A 121
GLN A 151
GLU A 157
 None
 0.52A 3l2vA-5ejkA:
18.9		 3l2vA-5ejkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 5ejk GAG-PRO-POL
POLYPROTEIN
(Rous
sarcoma
virus) 		4 / 8 ASP A  64
ASP A 121
PRO A 147
GLU A 157
 None
 0.52A 3oyaA-5ejkA:
19.1		 3oyaA-5ejkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3M_A_DLUA398_1
(PFV INTEGRASE)		 5ejk GAG-PRO-POL
POLYPROTEIN
(Rous
sarcoma
virus) 		4 / 8 ASP A  64
ASP A 121
GLY A 123
GLU A 157
 None
 0.60A 3s3mA-5ejkA:
18.9		 3s3mA-5ejkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3N_A_DLUA398_1
(PFV INTEGRASE)		 5ejk GAG-PRO-POL
POLYPROTEIN
(Rous
sarcoma
virus) 		4 / 8 ASP A  64
ASP A 121
GLY A 123
GLU A 157
 None
 0.61A 3s3nA-5ejkA:
19.1		 3s3nA-5ejkA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA612_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5ejk GAG-PRO-POL
POLYPROTEIN
(Rous
sarcoma
virus) 		3 / 3 LYS A 164
ASP A 165
ARG A 158
 None
 1.06A 5jwaA-5ejkA:
undetectable
5jwaH-5ejkA:
undetectable		 5jwaA-5ejkA:
18.70
5jwaH-5ejkA:
18.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOC_A_SAMA401_0
(PAVINE
N-METHYLTRANSFERASE)		 5ejk GAG-PRO-POL
POLYPROTEIN
(Rous
sarcoma
virus) 		5 / 12 GLY A  56
GLN A  59
VAL A 241
ALA A 248
LEU A 240
 None
 1.03A 5kocA-5ejkA:
undetectable		 5kocA-5ejkA:
18.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N0X_B_SAMB501_0
(PEPTIDE
N-METHYLTRANSFERASE)		 5ejk GAG-PRO-POL
POLYPROTEIN
(Rous
sarcoma
virus) 		5 / 12 ILE A  88
HIS A 212
VAL A 111
ALA A 159
MET A 163
 None
 1.29A 5n0xB-5ejkA:
undetectable		 5n0xB-5ejkA:
22.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F7L_B_ACTB505_0
(AMINE OXIDASE LKCE)		 5ejk GAG-PRO-POL
POLYPROTEIN
(Rous
sarcoma
virus) 		3 / 3 HIS A 198
ASN A 197
LEU A 196
 None
 0.90A 6f7lB-5ejkA:
undetectable		 6f7lB-5ejkA:
19.02