SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ekq'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_A_VIBA501_1
(YKOF)		 5ekq OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMC
OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAME
(Escherichia
coli) 		4 / 8 PHE E  74
SER E  65
ILE C  57
THR E  72
 None
 0.78A 1sbrA-5ekqE:
undetectable		 1sbrA-5ekqE:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SBR_B_VIBB503_1
(YKOF)		 5ekq OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMC
OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAME
(Escherichia
coli) 		4 / 7 PHE E  74
SER E  65
ILE C  57
THR E  72
 None
 0.74A 1sbrB-5ekqE:
undetectable		 1sbrB-5ekqE:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2CML_B_ZMRB2477_1
(NEURAMINIDASE)		 5ekq OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMC
(Escherichia
coli) 		5 / 12 ASP C 190
ALA C  79
ARG C  33
ARG C 196
TYR C 157
 None
 1.39A 2cmlB-5ekqC:
undetectable		 2cmlB-5ekqC:
23.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPN_B_ZMRB700_1
(NEURAMINIDASE)		 5ekq OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMC
(Escherichia
coli) 		5 / 12 ASP C 190
ALA C  79
ARG C  33
ARG C 196
TYR C 157
 None
 1.36A 4cpnB-5ekqC:
undetectable		 4cpnB-5ekqC:
20.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_C_ZMRC1470_1
(NEURAMINIDASE)		 5ekq OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMC
(Escherichia
coli) 		5 / 12 ASP C 190
ALA C  79
ARG C  33
ARG C 196
TYR C 157
 None
 1.38A 4cpzC-5ekqC:
undetectable		 4cpzC-5ekqC:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_E_ZMRE1471_1
(NEURAMINIDASE)		 5ekq OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMC
(Escherichia
coli) 		5 / 12 ASP C 190
ALA C  79
ARG C  33
ARG C 196
TYR C 157
 None
 1.33A 4cpzE-5ekqC:
undetectable		 4cpzE-5ekqC:
20.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CPZ_G_ZMRG1471_1
(NEURAMINIDASE)		 5ekq OUTER MEMBRANE
PROTEIN ASSEMBLY
FACTOR BAMC
(Escherichia
coli) 		5 / 12 ASP C 190
ALA C  79
ARG C  33
ARG C 196
TYR C 157
 None
 1.34A 4cpzG-5ekqC:
undetectable		 4cpzG-5ekqC:
20.25