SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5elg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_C_DVAC6_0
(GRAMICIDIN A)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		3 / 3 ALA A  10
VAL A 203
TRP A 207
 None
None
GOL  A 301 (-3.3A)
 0.81A 1c4dC-5elgA:
undetectable
1c4dD-5elgA:
undetectable		 1c4dC-5elgA:
10.81
1c4dD-5elgA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C4D_D_DVAD6_0
(GRAMICIDIN A)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		3 / 3 TRP A 207
ALA A  10
VAL A 203
 GOL  A 301 (-3.3A)
None
None
 0.73A 1c4dC-5elgA:
undetectable
1c4dD-5elgA:
undetectable		 1c4dC-5elgA:
10.81
1c4dD-5elgA:
10.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		3 / 3 ALA A  10
VAL A 203
TRP A 207
 None
None
GOL  A 301 (-3.3A)
 0.91A 1tkqB-5elgA:
undetectable		 1tkqB-5elgA:
10.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_A_ICFA1_1
(INTEGRIN ALPHA-L)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 9 ILE A  39
LEU A  30
GLU A  31
LEU A  27
LYS A 195
 None
 1.24A 3f78A-5elgA:
undetectable		 3f78A-5elgA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F78_B_ICFB2_1
(INTEGRIN ALPHA-L)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 9 ILE A  39
LEU A  30
GLU A  31
LEU A  27
LYS A 195
 None
 1.29A 3f78B-5elgA:
undetectable		 3f78B-5elgA:
23.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 12 THR A 198
ASP A  19
VAL A 203
PHE A 103
PHE A 106
 None
GOL  A 301 (-2.9A)
None
None
None
 1.37A 3nyaA-5elgA:
undetectable		 3nyaA-5elgA:
18.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_B_CLMB221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 12 THR A  91
SER A 148
LEU A 130
VAL A 180
HIS A 133
 None
 1.40A 3u9fB-5elgA:
undetectable
3u9fC-5elgA:
undetectable		 3u9fB-5elgA:
23.77
3u9fC-5elgA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_J_CLMJ221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 12 THR A  91
SER A 148
LEU A 130
VAL A 180
HIS A 133
 None
 1.41A 3u9fJ-5elgA:
undetectable
3u9fK-5elgA:
undetectable		 3u9fJ-5elgA:
23.77
3u9fK-5elgA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_L_CLML221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 12 HIS A 133
THR A  91
SER A 148
LEU A 130
VAL A 180
 None
 1.36A 3u9fJ-5elgA:
undetectable
3u9fL-5elgA:
undetectable		 3u9fJ-5elgA:
23.77
3u9fL-5elgA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U9F_S_CLMS221_0
(CHLORAMPHENICOL
ACETYLTRANSFERASE)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 12 HIS A 133
THR A  91
SER A 148
LEU A 130
VAL A 180
 None
 1.41A 3u9fP-5elgA:
undetectable
3u9fS-5elgA:
undetectable		 3u9fP-5elgA:
23.77
3u9fS-5elgA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		4 / 7 LEU A 165
GLN A 162
PHE A 106
LEU A 110
 None
 0.99A 3x2qP-5elgA:
undetectable
3x2qW-5elgA:
undetectable		 3x2qP-5elgA:
20.86
3x2qW-5elgA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 12 LEU A  27
GLY A  18
CYH A  20
ALA A   9
ASN A  43
 None
None
GSH  A 302 (-3.0A)
None
None
 1.09A 4pclB-5elgA:
undetectable		 4pclB-5elgA:
23.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PCL_B_SAMB301_0
(O-METHYLTRANSFERASE
FAMILY PROTEIN)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 12 LEU A  27
GLY A  18
CYH A  20
ALA A  13
ALA A   9
 None
None
GSH  A 302 (-3.0A)
None
None
 1.38A 4pclB-5elgA:
undetectable		 4pclB-5elgA:
23.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D9W_A_ASCA301_0
(DEHYDROASCORBATE
REDUCTASE)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 9 ASP A  19
PHE A 106
HIS A 160
GLY A 206
TRP A 207
 GOL  A 301 (-2.9A)
None
GOL  A 301 ( 4.9A)
GOL  A 301 (-3.8A)
GOL  A 301 (-3.3A)
 1.42A 5d9wA-5elgA:
34.3		 5d9wA-5elgA:
61.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D9W_A_ASCA301_0
(DEHYDROASCORBATE
REDUCTASE)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		7 / 9 ASP A  19
PRO A  21
PHE A 103
HIS A 160
GLY A 206
TRP A 207
LYS A 210
 GOL  A 301 (-2.9A)
GOL  A 301 ( 4.7A)
None
GOL  A 301 ( 4.9A)
GOL  A 301 (-3.8A)
GOL  A 301 (-3.3A)
GOL  A 301 (-2.6A)
 0.69A 5d9wA-5elgA:
34.3		 5d9wA-5elgA:
61.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5D9W_A_ASCA301_0
(DEHYDROASCORBATE
REDUCTASE)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		7 / 9 LYS A   8
ASP A  19
PRO A  21
PHE A 103
HIS A 160
GLY A 206
TRP A 207
 GOL  A 301 (-3.1A)
GOL  A 301 (-2.9A)
GOL  A 301 ( 4.7A)
None
GOL  A 301 ( 4.9A)
GOL  A 301 (-3.8A)
GOL  A 301 (-3.3A)
 0.44A 5d9wA-5elgA:
34.3		 5d9wA-5elgA:
61.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 3
CYTOCHROME C OXIDASE
SUBUNIT 7A1,
MITOCHONDRIAL)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		4 / 7 LEU A 165
GLN A 162
PHE A 106
LEU A 110
 None
 0.93A 5zcoC-5elgA:
undetectable
5zcoJ-5elgA:
undetectable		 5zcoC-5elgA:
20.86
5zcoJ-5elgA:
15.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_A_5FWA401_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 12 THR A 198
ASP A  19
VAL A 203
PHE A 103
PHE A 106
 None
GOL  A 301 (-2.9A)
None
None
None
 1.44A 6h7jA-5elgA:
undetectable		 6h7jA-5elgA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7J_B_5FWB402_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 12 THR A 198
ASP A  19
VAL A 203
PHE A 103
PHE A 106
 None
GOL  A 301 (-2.9A)
None
None
None
 1.45A 6h7jB-5elgA:
undetectable		 6h7jB-5elgA:
18.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6H7M_A_68HA504_0
(BETA-1 ADRENERGIC
RECEPTOR)		 5elg GLUTATHIONE
S-TRANSFERASE DHAR1,
MITOCHONDRIAL
(Arabidopsis
thaliana) 		5 / 12 THR A 198
ASP A  19
VAL A 203
PHE A 103
PHE A 106
 None
GOL  A 301 (-2.9A)
None
None
None
 1.43A 6h7mA-5elgA:
undetectable		 6h7mA-5elgA:
18.88