SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5elh'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1P9G_A_ACTA42_0 (EAFP 2)	5elh	RING FINGER PROTEIN UNKEMPT HOMOLOG (Mus musculus)	3 / 3	CYH A 106 ARG A 72 CYH A 90	ZN A 202 (-2.3A) None ZN A 202 (-2.2A)	1.15A	1p9gA-5elhA: undetectable	1p9gA-5elhA: 17.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2IWK_B_CUB1599_0 (NITROUS OXIDE REDUCTASE)	5elh	RING FINGER PROTEIN UNKEMPT HOMOLOG (Mus musculus)	3 / 3	CYH A 53 CYH A 61 HIS A 65	ZN A 201 (-2.3A) ZN A 201 (-2.3A) ZN A 201 (-3.2A)	0.87A	2iwkB-5elhA: undetectable	2iwkB-5elhA: 11.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3W9T_B_W9TB513_1 (HEMOLYTIC LECTIN CEL-III)	5elh	RING FINGER PROTEIN UNKEMPT HOMOLOG (Mus musculus)	4 / 6	CYH A 140 THR A 141 CYH A 147 ILE A 129	ZN A 203 (-2.4A) None ZN A 203 (-2.3A) None	1.32A	3w9tB-5elhA: undetectable	3w9tB-5elhA: 15.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5AYF_A_C7HA402_1 (HISTONE-LYSINE N-METHYLTRANSFERASE SETD7)	5elh	RING FINGER PROTEIN UNKEMPT HOMOLOG (Mus musculus)	4 / 5	TYR A 36 GLY A 144 TYR A 120 GLY A 114	None	1.03A	5ayfA-5elhA: undetectable	5ayfA-5elhA: 15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6FBV_D_FI8D1904_1 (DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA')	5elh	RING FINGER PROTEIN UNKEMPT HOMOLOG (Mus musculus)	4 / 8	ASP A 104 ARG A 72 GLU A 43 GLN A 32	None	1.01A	6fbvD-5elhA: undetectable	6fbvD-5elhA: 8.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6MA7_A_TPFA602_0 (CYTOCHROME P450 3A4)	5elh	RING FINGER PROTEIN UNKEMPT HOMOLOG (Mus musculus)	4 / 7	ARG A 71 SER A 74 THR A 127 ALA A 148	None	0.95A	6ma7A-5elhA: undetectable	6ma7A-5elhA: 17.81

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1P9G_A_ACTA42_0","EAFP 2","5elh","RING FINGER PROTEIN UNKEMPT HOMOLOG","Mus musculus",3,"CYH A 106;ARG A  72;CYH A  90"," ZN A 202 (-2.3A);None; ZN A 202 (-2.2A)","1.15A","1p9gA-5elhA:undetectable","1p9gA-5elhA:17.92"],["2IWK_B_CUB1599_0","NITROUS OXIDE REDUCTASE","5elh","RING FINGER PROTEIN UNKEMPT HOMOLOG","Mus musculus",3,"CYH A  53;CYH A  61;HIS A  65"," ZN A 201 (-2.3A); ZN A 201 (-2.3A); ZN A 201 (-3.2A)","0.87A","2iwkB-5elhA:undetectable","2iwkB-5elhA:11.72"],["3W9T_B_W9TB513_1","HEMOLYTIC LECTIN CEL-III","5elh","RING FINGER PROTEIN UNKEMPT HOMOLOG","Mus musculus",4,"CYH A 140;THR A 141;CYH A 147;ILE A 129"," ZN A 203 (-2.4A);None; ZN A 203 (-2.3A);None","1.32A","3w9tB-5elhA:undetectable","3w9tB-5elhA:15.22"],["5AYF_A_C7HA402_1","HISTONE-LYSINE N-METHYLTRANSFERASE SETD7","5elh","RING FINGER PROTEIN UNKEMPT HOMOLOG","Mus musculus",4,"TYR A  36;GLY A 144;TYR A 120;GLY A 114","None","1.03A","5ayfA-5elhA:undetectable","5ayfA-5elhA:15.59"],["6FBV_D_FI8D1904_1","DNA-DIRECTED RNA POLYMERASE SUBUNIT BETA'","5elh","RING FINGER PROTEIN UNKEMPT HOMOLOG","Mus musculus",4,"ASP A 104;ARG A  72;GLU A  43;GLN A  32","None","1.01A","6fbvD-5elhA:undetectable","6fbvD-5elhA:8.38"],["6MA7_A_TPFA602_0","CYTOCHROME P450 3A4","5elh","RING FINGER PROTEIN UNKEMPT HOMOLOG","Mus musculus",4,"ARG A  71;SER A  74;THR A 127;ALA A 148","None","0.95A","6ma7A-5elhA:undetectable","6ma7A-5elhA:17.81"]]