SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5elp'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DIT_P_2PPP1_1
(ALPHA-THROMBIN
PEPTIDE INHIBITOR
CVS995)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 6 LEU C 394
ILE C 348
GLU C 328
ASP C 325
 None
 1.03A 1ditH-5elpC:
undetectable
1ditP-5elpC:
undetectable		 1ditH-5elpC:
18.37
1ditP-5elpC:
3.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_A_SAMA293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		3 / 3 ARG C 491
ASP C  26
ASN C  32
 None
 0.82A 1nbhA-5elpC:
undetectable		 1nbhA-5elpC:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NBH_D_SAMD3293_1
(GLYCINE
N-METHYLTRANSFERASE)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		3 / 3 ARG C 491
ASP C  26
ASN C  32
 None
 0.81A 1nbhD-5elpC:
undetectable		 1nbhD-5elpC:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1VPO_H_TESH1010_1
(ANTI-TESTOSTERONE
(HEAVY CHAIN)
ANTI-TESTOSTERONE
(LIGHT CHAIN))		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		5 / 12 SER C 184
GLY C 247
LEU C 358
PHE C  21
VAL C 251
 None
 1.14A 1vpoH-5elpC:
undetectable
1vpoL-5elpC:
undetectable		 1vpoH-5elpC:
16.34
1vpoL-5elpC:
14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X7P_B_SAMB302_0
(RRNA
METHYLTRANSFERASE)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		5 / 10 GLY C 249
GLY C 207
ILE C 107
LEU C 252
ALA C 106
 None
 1.14A 1x7pA-5elpC:
undetectable
1x7pB-5elpC:
undetectable		 1x7pA-5elpC:
17.94
1x7pB-5elpC:
17.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1507_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		3 / 3 GLN C 435
HIS C 415
ARG C 413
 None
 0.92A 1zlqA-5elpC:
undetectable		 1zlqA-5elpC:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HMY_B_SAMB328_0
(PROTEIN
(CYTOSINE-SPECIFIC
METHYLTRANSFERASE
HHAI))		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		5 / 12 GLY C 206
GLY C 187
ILE C 107
LEU C 168
VAL C 177
 None
 0.82A 2hmyB-5elpC:
undetectable		 2hmyB-5elpC:
18.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZMB_A_PXBA692_1
(LACTOTRANSFERRIN)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		3 / 3 PRO C 588
GLU C 463
TYR C 464
 None
 0.77A 2zmbA-5elpC:
undetectable		 2zmbA-5elpC:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_B_IMNB3_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		5 / 12 ILE C 273
ALA C 259
ILE C 266
LEU C 252
VAL C 251
 None
 1.01A 3adsB-5elpC:
undetectable		 3adsB-5elpC:
19.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BPX_A_SALA257_1
(TRANSCRIPTIONAL
REGULATOR)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 8 SER C 125
ALA C 179
THR C 429
THR C 427
 None
 0.95A 3bpxA-5elpC:
undetectable
3bpxB-5elpC:
undetectable		 3bpxA-5elpC:
14.98
3bpxB-5elpC:
14.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3D4S_A_TIMA401_2
(BETA-2 ADRENERGIC
RECEPTOR/T4-LYSOZYME
CHIMERA)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		3 / 3 THR C 429
SER C 421
PHE C 433
 None
 0.76A 3d4sA-5elpC:
undetectable		 3d4sA-5elpC:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MED_A_65BA561_0
(P51 REVERSE
TRANSCRIPTASE
P66 REVERSE
TRANSCRIPTASE)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		5 / 12 LEU C 329
VAL C 314
GLY C 347
LEU C 394
GLU C 328
 None
 1.33A 3medA-5elpC:
undetectable
3medB-5elpC:
undetectable		 3medA-5elpC:
23.00
3medB-5elpC:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N8Z_B_FLPB1701_1
(PROSTAGLANDIN G/H
SYNTHASE 1)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		5 / 12 LEU C 419
ILE C 368
GLY C 366
ALA C 365
LEU C 355
 None
 1.08A 3n8zB-5elpC:
undetectable		 3n8zB-5elpC:
22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3R9S_C_BEZC264_0
(CARNITINYL-COA
DEHYDRATASE)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 6 ALA C 234
ILE C 232
GLU C 328
ALA C 316
 None
 0.90A 3r9sC-5elpC:
undetectable		 3r9sC-5elpC:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_A_ACTA604_0
(GBAA_1210 PROTEIN)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 6 GLY C 207
HIS C 178
SER C 125
THR C 209
 None
 1.00A 3tj7A-5elpC:
undetectable
3tj7B-5elpC:
undetectable		 3tj7A-5elpC:
14.81
3tj7B-5elpC:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_C_ACTC606_0
(GBAA_1210 PROTEIN)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 6 GLY C 207
HIS C 178
SER C 125
THR C 209
 None
 1.00A 3tj7C-5elpC:
undetectable
3tj7D-5elpC:
undetectable		 3tj7C-5elpC:
14.81
3tj7D-5elpC:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TJ7_D_ACTD605_0
(GBAA_1210 PROTEIN)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 6 HIS C 178
SER C 125
THR C 209
GLY C 207
 None
 1.03A 3tj7C-5elpC:
undetectable
3tj7D-5elpC:
undetectable		 3tj7C-5elpC:
14.81
3tj7D-5elpC:
14.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_B_W9TB501_1
(HEMOLYTIC LECTIN
CEL-III)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 5 ASP C 229
SER C 227
GLY C 241
ASP C 238
 None
 1.42A 3w9tB-5elpC:
undetectable		 3w9tB-5elpC:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1003_1
(HEMOLYTIC LECTIN
CEL-III)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 5 ASP C 229
SER C 227
GLY C 241
ASP C 238
 None
 1.43A 3w9tC-5elpC:
undetectable		 3w9tC-5elpC:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD501_1
(HEMOLYTIC LECTIN
CEL-III)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 5 ASP C 229
SER C 227
GLY C 241
ASP C 238
 None
 1.43A 3w9tD-5elpC:
undetectable		 3w9tD-5elpC:
18.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6E_A_SAMA1349_0
(HYDROXYINDOLE
O-METHYLTRANSFERASE)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		5 / 12 LEU C 185
ILE C  17
VAL C 251
PHE C  30
ALA C 362
 None
 1.12A 4a6eA-5elpC:
undetectable		 4a6eA-5elpC:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GC9_A_ACTA402_0
(DIMETHYLADENOSINE
TRANSFERASE 1,
MITOCHONDRIAL)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		3 / 3 LYS C 583
TYR C 485
ARG C 584
 None
 1.15A 4gc9A-5elpC:
undetectable		 4gc9A-5elpC:
19.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_A_SAMA301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		5 / 12 GLY C 245
GLY C 247
LEU C  71
ALA C 362
GLU C  39
 None
 1.04A 4lg1A-5elpC:
undetectable		 4lg1A-5elpC:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LG1_B_SAMB301_0
(PROTEIN-LYSINE
METHYLTRANSFERASE
METTL21D)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		5 / 12 GLY C 245
GLY C 247
LEU C  71
ALA C 362
GLU C  39
 None
 1.07A 4lg1B-5elpC:
undetectable		 4lg1B-5elpC:
18.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA604_1
(TRANSPORTER)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 7 ILE C 348
LEU C 329
ASP C 325
THR C 321
 None
 0.96A 4mmcA-5elpC:
undetectable		 4mmcA-5elpC:
22.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 5 SER C 420
ALA C 316
HIS C 430
LEU C 332
 None
 1.36A 5dzkb-5elpC:
undetectable
5dzkp-5elpC:
undetectable		 5dzkb-5elpC:
15.27
5dzkp-5elpC:
1.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_Q_BEZQ801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 5 SER C 420
ALA C 316
HIS C 430
LEU C 332
 None
 1.40A 5dzkc-5elpC:
undetectable
5dzkq-5elpC:
undetectable		 5dzkc-5elpC:
15.27
5dzkq-5elpC:
1.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_T_BEZT801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 5 SER C 420
ALA C 316
HIS C 430
LEU C 332
 None
 1.40A 5dzkf-5elpC:
undetectable
5dzkt-5elpC:
undetectable		 5dzkf-5elpC:
15.27
5dzkt-5elpC:
1.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 7 GLU C  39
GLY C 230
GLY C 244
ALA C  67
 None
 0.87A 5e26C-5elpC:
undetectable
5e26D-5elpC:
undetectable		 5e26C-5elpC:
20.95
5e26D-5elpC:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IQB_A_KANA600_1
(BIFUNCTIONAL AAC/APH)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		5 / 12 ASP C 278
ASN C 276
ASP C 281
SER C 420
GLU C 328
 None
 1.33A 5iqbA-5elpC:
undetectable		 5iqbA-5elpC:
18.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_A_PCFA1808_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 5 LEU C 461
LYS C 462
ALA C 465
LEU C 468
 None
 0.78A 5vkqA-5elpC:
undetectable
5vkqD-5elpC:
undetectable		 5vkqA-5elpC:
16.11
5vkqD-5elpC:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_B_PCFB1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 5 LEU C 461
LYS C 462
ALA C 465
LEU C 468
 None
 0.78A 5vkqA-5elpC:
undetectable
5vkqB-5elpC:
undetectable		 5vkqA-5elpC:
16.11
5vkqB-5elpC:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1805_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		5 / 9 GLY C  16
LEU C 252
LEU C 100
GLY C 111
PHE C  82
 None
 0.80A 5vkqC-5elpC:
undetectable
5vkqD-5elpC:
undetectable		 5vkqC-5elpC:
16.11
5vkqD-5elpC:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_C_PCFC1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 5 LEU C 461
LYS C 462
ALA C 465
LEU C 468
 None
 0.77A 5vkqB-5elpC:
undetectable
5vkqC-5elpC:
undetectable		 5vkqB-5elpC:
16.11
5vkqC-5elpC:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VKQ_D_PCFD1806_0
(NO MECHANORECEPTOR
POTENTIAL C ISOFORM
L)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 5 LEU C 461
LYS C 462
ALA C 465
LEU C 468
 None
 0.78A 5vkqC-5elpC:
undetectable
5vkqD-5elpC:
undetectable		 5vkqC-5elpC:
16.11
5vkqD-5elpC:
16.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 7 LEU C 270
HIS C 317
THR C 429
HIS C 357
 None
 1.14A 5w97C-5elpC:
undetectable
5w97a-5elpC:
undetectable
5w97c-5elpC:
undetectable		 5w97C-5elpC:
17.77
5w97a-5elpC:
20.97
5w97c-5elpC:
17.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X6Y_C_SAMC902_0
(MRNA CAPPING ENZYME
P5)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		5 / 12 GLY C 426
PRO C 288
ALA C 287
ASP C 278
THR C 427
 None
 1.14A 5x6yC-5elpC:
undetectable		 5x6yC-5elpC:
21.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 8 ILE C 107
LEU C 170
ALA C 200
LEU C 195
 None
 0.74A 5y7pE-5elpC:
undetectable		 5y7pE-5elpC:
19.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GTQ_B_ACTB207_0
(DUF1778
DOMAIN-CONTAINING
PROTEIN
N-ACETYLTRANSFERASE)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 6 LEU C 587
THR C 486
GLY C 111
ARG C 491
 None
 1.39A 6gtqB-5elpC:
undetectable
6gtqD-5elpC:
undetectable		 6gtqB-5elpC:
14.93
6gtqD-5elpC:
5.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6MN5_B_LLLB301_0
(AMINOGLYCOSIDE
N(3)-ACETYLTRANSFERA
SE, AAC(3)-IVA)		 5elp NRPS/PKS PROTEIN
(Bacillus
amyloliquefacien
s) 		4 / 7 ASP C  78
ARG C 460
TYR C 590
ASP C 459
 None
 1.13A 6mn5B-5elpC:
undetectable		 6mn5B-5elpC:
10.02