SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5elr'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A29_A_TFPA154_1 (CALMODULIN)	5elr	KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIA TED PROTEIN 3 (Homo sapiens)	5 / 10	ALA C 107 MET C 103 GLU C 109 LEU C 123 GLU C 117	None	1.45A	1a29A-5elrC: undetectable	1a29A-5elrC: 26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1A29_A_TFPA154_1 (CALMODULIN)	5elr	KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIA TED PROTEIN 3 (Homo sapiens)	5 / 10	GLU C 110 ALA C 107 MET C 103 LEU C 123 GLU C 117	None	1.19A	1a29A-5elrC: undetectable	1a29A-5elrC: 26.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2QXS_A_RALA600_2 (ESTROGEN RECEPTOR)	5elr	KH DOMAIN-CONTAINING, RNA-BINDING, SIGNAL TRANSDUCTION-ASSOCIA TED PROTEIN 3 (Homo sapiens)	4 / 5	LEU C 127 ASP C 125 MET C 95 LEU C 84	None None None A B 7 ( 4.9A)	1.30A	2qxsA-5elrC: undetectable	2qxsA-5elrC: 19.69