SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5elt'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ERR_A_RALA600_2
(ESTROGEN RECEPTOR)
5elt KH
DOMAIN-CONTAINING,
RNA-BINDING, SIGNAL
TRANSDUCTION-ASSOCIA
TED PROTEIN 3

(Homo
sapiens)
4 / 6 LEU B  56
LEU B 148
LEU B  87
LEU B  84
None
None
None
A  E   2 ( 4.8A)
0.85A 1errA-5eltB:
undetectable
1errA-5eltB:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_A_EVPA1_1
(DNA TOPOISOMERASE
2-BETA)
5elt KH
DOMAIN-CONTAINING,
RNA-BINDING, SIGNAL
TRANSDUCTION-ASSOCIA
TED PROTEIN 3

(Homo
sapiens)
4 / 5 GLY B  99
ASP B 125
GLN B  58
MET B 144
None
1.18A 3qx3A-5eltB:
undetectable
3qx3A-5eltB:
13.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QX3_D_EVPD1_1
(DNA TOPOISOMERASE
2-BETA)
5elt KH
DOMAIN-CONTAINING,
RNA-BINDING, SIGNAL
TRANSDUCTION-ASSOCIA
TED PROTEIN 3

(Homo
sapiens)
4 / 5 GLY B  99
ASP B 125
GLN B  58
MET B 144
None
1.12A 3qx3B-5eltB:
undetectable
3qx3B-5eltB:
13.73