SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5elz'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MUI_B_AB1B100_2
(PROTEASE)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 12 GLY A  51
ALA A   7
ILE A  14
GLY A   4
ILE A  57
 None
 0.88A 1muiB-5elzA:
undetectable		 1muiB-5elzA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		3 / 3 GLY A  51
GLU A  70
ASN A  53
 None
3V9  A 303 (-3.2A)
None
 0.49A 1zq9A-5elzA:
undetectable		 1zq9A-5elzA:
22.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVS_B_MK1B902_1
(POL POLYPROTEIN)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 12 ALA A  95
ILE A 117
GLY A 116
GLY A 115
VAL A 114
 None
None
3V9  A 303 (-3.2A)
None
None
 0.88A 2avsA-5elzA:
undetectable		 2avsA-5elzA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2H77_A_T3A1_1
(THRA PROTEIN)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 12 ALA A 262
ALA A  65
LEU A  49
LEU A  39
ILE A  63
 None
 1.00A 2h77A-5elzA:
undetectable		 2h77A-5elzA:
23.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKP_C_478C200_2
(PROTEASE)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 10 GLY A  51
ALA A   7
ILE A  14
GLY A   4
ILE A  57
 None
 0.87A 3ekpD-5elzA:
undetectable		 3ekpD-5elzA:
20.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKQ_A_ROCA100_1
(PROTEASE)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		6 / 12 GLY A  51
ALA A   7
ILE A  14
VAL A  15
GLY A   4
ILE A  57
 None
 1.01A 3ekqA-5elzA:
undetectable		 3ekqA-5elzA:
19.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM4_V_DR7V100_1
(PROTEASE)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 11 GLY A  51
ALA A   7
ILE A  14
GLY A   4
ILE A  57
 None
 0.89A 3em4U-5elzA:
undetectable		 3em4U-5elzA:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_A_PAUA602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 7 GLU A  70
GLY A 100
SER A 102
ARG A 113
GLY A 116
 3V9  A 303 (-3.2A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.8A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.2A)
 0.50A 5e26A-5elzA:
29.5
5e26B-5elzA:
29.6		 5e26A-5elzA:
26.26
5e26B-5elzA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_B_PAUB601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 7 GLU A  70
GLY A 100
SER A 102
ARG A 113
GLY A 116
 3V9  A 303 (-3.2A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.8A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.2A)
 0.44A 5e26A-5elzA:
29.5
5e26B-5elzA:
29.6		 5e26A-5elzA:
26.26
5e26B-5elzA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_C_PAUC602_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 7 GLU A  70
GLY A 100
SER A 102
ARG A 113
GLY A 116
 3V9  A 303 (-3.2A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.8A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.2A)
 0.44A 5e26C-5elzA:
29.8
5e26D-5elzA:
29.8		 5e26C-5elzA:
26.26
5e26D-5elzA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 8 GLU A  70
GLY A 100
SER A 102
ARG A 113
GLY A 116
 3V9  A 303 (-3.2A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.8A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.2A)
 0.46A 5e26C-5elzA:
29.8
5e26D-5elzA:
29.9		 5e26C-5elzA:
26.26
5e26D-5elzA:
26.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JGL_A_SAMA301_1
(UBIE/COQ5 FAMILY
METHYLTRANSFERASE,
PUTATIVE)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		3 / 3 GLY A 258
ASP A   6
ASN A  53
 None
MG  A 302 ( 4.1A)
None
 0.51A 5jglA-5elzA:
undetectable		 5jglA-5elzA:
23.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KOX_A_RFPA502_1
(PENTACHLOROPHENOL
4-MONOOXYGENASE)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 12 GLY A 201
GLY A 254
THR A  99
GLY A 121
GLY A 120
 None
None
ADP  A 301 ( 3.4A)
ADP  A 301 (-3.2A)
None
 0.80A 5koxA-5elzA:
undetectable		 5koxA-5elzA:
23.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KPR_A_PAUA404_0
(PANTOTHENATE KINASE
3)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 5 GLU A  70
GLY A 100
SER A 102
ARG A 113
GLY A 116
 3V9  A 303 (-3.2A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.8A)
3V9  A 303 (-3.3A)
3V9  A 303 (-3.2A)
 0.54A 5kprA-5elzA:
29.8		 5kprA-5elzA:
24.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5MUG_A_VIVA301_0
(ALPHA-TOCOPHEROL
TRANSFER PROTEIN)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 12 ILE A  32
ILE A  63
LEU A  39
VAL A  35
ILE A   5
 None
 1.08A 5mugA-5elzA:
undetectable		 5mugA-5elzA:
20.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_A_ACRA602_1
(-)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 12 GLY A 198
GLY A 201
VAL A 237
GLN A 145
VAL A  97
 UNX  A 304 ( 4.2A)
None
None
None
None
 1.15A 6gneA-5elzA:
undetectable		 6gneA-5elzA:
22.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNE_B_ACRB602_1
(-)		 5elz TYPE II PANTOTHENATE
KINASE
(Staphylococcus
aureus) 		5 / 12 GLY A 198
GLY A 201
VAL A 237
GLN A 145
VAL A  97
 UNX  A 304 ( 4.2A)
None
None
None
None
 1.16A 6gneB-5elzA:
undetectable		 6gneB-5elzA:
22.09