SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ema'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXK_A_IMNA2001_1
(SERUM ALBUMIN)		 5ema SORTING NEXIN-27
(Rattus
norvegicus) 		4 / 8 SER A  82
PHE A  55
ARG A 122
LEU A 128
 None
 0.75A 2bxkA-5emaA:
undetectable		 2bxkA-5emaA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2BXM_A_IMNA2001_1
(SERUM ALBUMIN)		 5ema SORTING NEXIN-27
(Rattus
norvegicus) 		4 / 8 SER A  82
PHE A  55
ARG A 122
LEU A 128
 None
 0.83A 2bxmA-5emaA:
undetectable		 2bxmA-5emaA:
10.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EM3_B_478B200_1
(PROTEASE)		 5ema SORTING NEXIN-27
(Rattus
norvegicus) 		5 / 10 LEU A 130
GLY A  94
ALA A  93
GLY A  88
ILE A  46
 None
 0.93A 3em3A-5emaA:
undetectable		 3em3A-5emaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUJ_B_478B401_2
(PROTEASE)		 5ema SORTING NEXIN-27
(Rattus
norvegicus) 		5 / 9 LEU A 130
GLY A  94
ALA A  93
GLY A  88
ILE A  46
 None
 0.93A 3nujB-5emaA:
undetectable		 3nujB-5emaA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NUO_B_478B478_2
(PROTEASE)		 5ema SORTING NEXIN-27
(Rattus
norvegicus) 		5 / 9 LEU A 130
GLY A  94
ALA A  93
GLY A  88
ILE A  46
 None
 0.92A 3nuoB-5emaA:
undetectable		 3nuoB-5emaA:
21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_B_478B200_1
(HIV-1 PROTEASE)		 5ema SORTING NEXIN-27
(Rattus
norvegicus) 		5 / 9 LEU A 130
GLY A  94
ALA A  93
GLY A  88
ILE A  46
 None
 0.93A 3oxvA-5emaA:
undetectable		 3oxvA-5emaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OXV_C_478C200_1
(HIV-1 PROTEASE)		 5ema SORTING NEXIN-27
(Rattus
norvegicus) 		5 / 9 LEU A 130
GLY A  94
ALA A  93
GLY A  88
ILE A  46
 None
 0.89A 3oxvC-5emaA:
undetectable		 3oxvC-5emaA:
21.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_B_478B101_2
(HIV-1 PROTEASE)		 5ema SORTING NEXIN-27
(Rattus
norvegicus) 		5 / 9 LEU A 130
GLY A  94
ALA A  93
GLY A  88
ILE A  46
 None
 0.89A 4rvjB-5emaA:
undetectable		 4rvjB-5emaA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4RVJ_D_478D101_2
(HIV-1 PROTEASE)		 5ema SORTING NEXIN-27
(Rattus
norvegicus) 		5 / 9 LEU A 130
GLY A  94
ALA A  93
GLY A  88
ILE A  46
 None
 0.90A 4rvjD-5emaA:
undetectable		 4rvjD-5emaA:
24.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB6_B_ADNB401_1
(ADENOSINE KINASE)		 5ema SORTING NEXIN-27
(Rattus
norvegicus) 		5 / 12 GLY A  52
ALA A  89
GLY A  88
ALA A  90
ILE A  46
 None
 0.94A 5kb6B-5emaA:
undetectable		 5kb6B-5emaA:
16.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 5ema SORTING NEXIN-27
(Rattus
norvegicus) 		4 / 6 PHE A  55
ALA A  90
SER A  49
ASN A 105
 None
 1.02A 6f88A-5emaA:
undetectable		 6f88A-5emaA:
16.67