SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5en6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3SUF_B_SUEB1201_3 (NS3 PROTEASE, NS4A PROTEIN)	5en6	SMU-1 (Caenorhabditis elegans)	4 / 5	SER A 120 ARG A 124 PRO A 125 TYR A 126	None	1.41A	3sufC-5en6A: undetectable	3sufC-5en6A: 22.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3VT7_A_VDXA500_2 (VITAMIN D3 RECEPTOR)	5en6	SMU-1 (Caenorhabditis elegans)	4 / 4	LEU A 85 ILE A 145 TYR A 133 TYR A 78	None	1.39A	3vt7A-5en6A: undetectable	3vt7A-5en6A: 21.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G3R_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	5en6	SMU-1 (Caenorhabditis elegans)	4 / 6	TYR A 78 LEU A 61 VAL A 64 ASP A 102	None	1.15A	4g3rA-5en6A: undetectable	4g3rA-5en6A: 18.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4L4C_A_CAMA502_0 (CAMPHOR 5-MONOOXYGENASE)	5en6	SMU-1 (Caenorhabditis elegans)	4 / 6	TYR A 78 LEU A 61 VAL A 64 ASP A 102	None	1.10A	4l4cA-5en6A: undetectable	4l4cA-5en6A: 18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4NKX_A_STRA601_2 (STEROID 17-ALPHA-HYDROXYLASE /17,20 LYASE)	5en6	SMU-1 (Caenorhabditis elegans)	4 / 6	LEU A 106 ASP A 76 VAL A 97 ALA A 98	None	0.82A	4nkxA-5en6A: undetectable	4nkxA-5en6A: 18.63

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3SUF_B_SUEB1201_3","NS3 PROTEASE, NS4A PROTEIN;NS3 PROTEASE, NS4A PROTEIN","5en6","SMU-1","Caenorhabditis elegans",4,"SER A 120;ARG A 124;PRO A 125;TYR A 126","None","1.41A","3sufC-5en6A:undetectable","3sufC-5en6A:22.27"],["3VT7_A_VDXA500_2","VITAMIN D3 RECEPTOR","5en6","SMU-1","Caenorhabditis elegans",4,"LEU A  85;ILE A 145;TYR A 133;TYR A  78","None","1.39A","3vt7A-5en6A:undetectable","3vt7A-5en6A:21.35"],["4G3R_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","5en6","SMU-1","Caenorhabditis elegans",4,"TYR A  78;LEU A  61;VAL A  64;ASP A 102","None","1.15A","4g3rA-5en6A:undetectable","4g3rA-5en6A:18.94"],["4L4C_A_CAMA502_0","CAMPHOR 5-MONOOXYGENASE","5en6","SMU-1","Caenorhabditis elegans",4,"TYR A  78;LEU A  61;VAL A  64;ASP A 102","None","1.10A","4l4cA-5en6A:undetectable","4l4cA-5en6A:18.90"],["4NKX_A_STRA601_2","STEROID 17-ALPHA-HYDROXYLASE\/17,20 LYASE","5en6","SMU-1","Caenorhabditis elegans",4,"LEU A 106;ASP A  76;VAL A  97;ALA A  98","None","0.82A","4nkxA-5en6A:undetectable","4nkxA-5en6A:18.63"]]