SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5end'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1S19_A_MC9A500_0
(VITAMIN D3 RECEPTOR)		 5end 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Vibrio
cholerae) 		5 / 12 LEU A 239
VAL A 183
ILE A 219
LEU A  29
LEU A  28
 None
 1.11A 1s19A-5endA:
undetectable		 1s19A-5endA:
21.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_A_SAMA400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5end 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Vibrio
cholerae) 		5 / 12 ILE A  25
ALA A  24
GLY A  20
ILE A 219
GLY A  16
 None
 0.73A 2qe6A-5endA:
6.5		 2qe6A-5endA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QE6_B_SAMB400_0
(UNCHARACTERIZED
PROTEIN TFU_2867)		 5end 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Vibrio
cholerae) 		5 / 12 ILE A  25
ALA A  24
GLY A  20
ILE A 219
GLY A  16
 None
 0.78A 2qe6B-5endA:
6.2		 2qe6B-5endA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LM8_A_VIBA223_1
(THIAMINE
PYROPHOSPHOKINASE)		 5end 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Vibrio
cholerae) 		4 / 7 LEU A  13
LEU A  62
ASN A  89
THR A  65
 None
 0.96A 3lm8A-5endA:
2.8
3lm8C-5endA:
2.5		 3lm8A-5endA:
22.01
3lm8C-5endA:
22.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AC9_B_DXCB1473_0
(MJ0495-LIKE PROTEIN)		 5end 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Vibrio
cholerae) 		5 / 11 ILE A  25
ILE A  21
GLY A  20
VAL A 241
GLY A 214
 None
 1.10A 4ac9B-5endA:
7.2
4ac9C-5endA:
7.0		 4ac9B-5endA:
22.15
4ac9C-5endA:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEN_B_VDYB201_1
(CDL2.2)		 5end 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Vibrio
cholerae) 		5 / 10 ILE A 118
MET A 169
VAL A  84
ILE A  70
LEU A  74
 None
 1.11A 5ienB-5endA:
undetectable		 5ienB-5endA:
21.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DRX_A_H8GA1201_0
(5HT2B RECEPTOR, BRIL
CHIMERA)		 5end 3-OXOACYL-[ACYL-CARR
IER-PROTEIN]
REDUCTASE FABG
(Vibrio
cholerae) 		5 / 12 LEU A  87
VAL A 180
THR A 235
PHE A 165
VAL A 162
 None
 1.47A 6drxA-5endA:
undetectable		 6drxA-5endA:
21.20