SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5enf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T3S_C_9PLC1_1
(CYTOCHROME P450 2A13)		 5enf PH-INTERACTING
PROTEIN
(Homo
sapiens) 		4 / 7 PHE A1363
PHE A1414
PHE A1389
LEU A1381
 None
 1.09A 3t3sC-5enfA:
undetectable		 3t3sC-5enfA:
14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C66_A_H4CA1168_0
(BROMODOMAIN-CONTAINI
NG PROTEIN 4)		 5enf PH-INTERACTING
PROTEIN
(Homo
sapiens) 		5 / 9 PRO A1340
GLN A1343
VAL A1345
ILE A1403
MET A1406
 None
None
5Q7  A1503 (-4.0A)
5Q7  A1503 ( 3.9A)
None
 0.95A 4c66A-5enfA:
14.9		 4c66A-5enfA:
27.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X23_A_LSNA504_1
(CYTOCHROME P450 2C9)		 5enf PH-INTERACTING
PROTEIN
(Homo
sapiens) 		4 / 8 PHE A1414
ILE A1332
PHE A1389
PRO A1344
 None
 1.15A 5x23A-5enfA:
undetectable		 5x23A-5enfA:
12.79