SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5enu'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		6 / 10 PRO A  37
THR A  41
PRO A  42
GLY A  43
CYH A  44
ARG A 119
 None
 0.33A 1h4oA-5enuA:
19.0
1h4oB-5enuA:
19.1		 1h4oA-5enuA:
25.41
1h4oB-5enuA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		6 / 8 PRO A  37
THR A  41
PRO A  42
GLY A  43
CYH A  44
ARG A 119
 None
 0.37A 1h4oB-5enuA:
19.1		 1h4oB-5enuA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		6 / 9 PRO A  37
THR A  41
PRO A  42
GLY A  43
CYH A  44
ARG A 119
 None
 0.37A 1h4oC-5enuA:
18.9
1h4oD-5enuA:
18.9		 1h4oC-5enuA:
25.41
1h4oD-5enuA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		6 / 9 PRO A  37
THR A  41
PRO A  42
GLY A  43
CYH A  44
ARG A 119
 None
 0.36A 1h4oD-5enuA:
18.9		 1h4oD-5enuA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		6 / 9 PRO A  37
THR A  41
PRO A  42
GLY A  43
CYH A  44
ARG A 119
 None
 0.36A 1h4oE-5enuA:
19.0
1h4oF-5enuA:
18.9		 1h4oE-5enuA:
25.41
1h4oF-5enuA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		6 / 9 PRO A  37
THR A  41
PRO A  42
GLY A  43
CYH A  44
ARG A 119
 None
 0.35A 1h4oF-5enuA:
18.9		 1h4oF-5enuA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		6 / 8 PRO A  37
THR A  41
PRO A  42
GLY A  43
CYH A  44
ARG A 119
 None
 0.34A 1h4oG-5enuA:
18.9		 1h4oG-5enuA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		6 / 9 PRO A  37
THR A  41
PRO A  42
GLY A  43
CYH A  44
ARG A 119
 None
 0.33A 1h4oH-5enuA:
19.0		 1h4oH-5enuA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		6 / 9 PRO A  37
THR A  41
PRO A  42
GLY A  43
CYH A  44
ARG A 119
 None
 0.36A 1hd2A-5enuA:
19.0		 1hd2A-5enuA:
25.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		6 / 8 PRO A  37
THR A  41
PRO A  42
GLY A  43
CYH A  44
ARG A 119
 None
 0.35A 1oc3A-5enuA:
18.8		 1oc3A-5enuA:
27.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		6 / 9 PRO A  37
THR A  41
PRO A  42
GLY A  43
CYH A  44
ARG A 119
 None
 0.33A 1oc3B-5enuA:
18.6		 1oc3B-5enuA:
27.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1URM_A_BEZA201_0
(PEROXIREDOXIN 5)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		5 / 9 PRO A  37
THR A  41
PRO A  42
GLY A  43
ARG A 119
 None
 0.54A 1urmA-5enuA:
18.5		 1urmA-5enuA:
27.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		4 / 8 PRO A  37
THR A  41
PRO A  42
ARG A 119
 None
 0.40A 2v32C-5enuA:
19.2
2v32D-5enuA:
20.9		 2v32C-5enuA:
27.15
2v32D-5enuA:
27.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		4 / 8 PRO A  37
THR A  41
PRO A  42
ARG A 119
 None
 0.46A 2v41C-5enuA:
21.1
2v41D-5enuA:
21.2		 2v41C-5enuA:
27.15
2v41D-5enuA:
27.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_D_BEZD1222_0
(PEROXIREDOXIN 6.)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		4 / 8 PRO A  37
THR A  41
PRO A  42
ARG A 119
 None
 0.46A 2v41C-5enuA:
21.1
2v41D-5enuA:
21.2		 2v41C-5enuA:
27.15
2v41D-5enuA:
27.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		4 / 8 PRO A  37
THR A  41
PRO A  42
ARG A 119
 None
 0.45A 2v41G-5enuA:
19.2
2v41H-5enuA:
19.2		 2v41G-5enuA:
27.15
2v41H-5enuA:
27.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		6 / 10 PRO A  37
THR A  41
PRO A  42
GLY A  43
CYH A  44
ARG A 119
 None
 0.35A 2vl2A-5enuA:
18.9
2vl2C-5enuA:
16.6		 2vl2A-5enuA:
27.55
2vl2C-5enuA:
27.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		4 / 7 PRO A  37
THR A  41
PRO A  42
GLY A  43
 None
 0.33A 2vl2B-5enuA:
18.6		 2vl2B-5enuA:
27.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I73_A_68PA705_1
(SODIUM-DEPENDENT
SEROTONIN
TRANSPORTER)		 5enu ALKYL HYDROPEROXIDE
REDUCTASE/ THIOL
SPECIFIC
ANTIOXIDANT/ MAL
ALLERGEN
(Burkholderia
ambifaria) 		5 / 9 ARG A 135
PHE A 101
GLU A   4
PRO A  10
ILE A 124
 None
 1.24A 5i73A-5enuA:
undetectable		 5i73A-5enuA:
17.46