SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eo3'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELZ_B_CHDB200_0
(ILEAL BILE
ACID-BINDING PROTEIN)		 5eo3 PROTEIN PELOTA
HOMOLOG
(Homo
sapiens) 		4 / 5 PRO A 369
VAL A 370
THR A 342
GLY A 341
 None
 1.21A 3elzB-5eo3A:
undetectable		 3elzB-5eo3A:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_4
(PROTEASE)		 5eo3 PROTEIN PELOTA
HOMOLOG
(Homo
sapiens) 		4 / 4 ASP A 279
ASP A 280
GLY A 273
THR A 342
 None
 1.33A 3tl9B-5eo3A:
undetectable		 3tl9B-5eo3A:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OM3_B_DXTB501_1
(ALPHA-1-ANTICHYMOTRY
PSIN)		 5eo3 PROTEIN PELOTA
HOMOLOG
(Homo
sapiens) 		4 / 6 SER A 314
PHE A 346
ASP A 315
HIS A 350
 None
 1.01A 5om3A-5eo3A:
undetectable
5om3B-5eo3A:
undetectable		 5om3A-5eo3A:
25.42
5om3B-5eo3A:
19.51