SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eo6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TKQ_B_DVAB6_0
(GRAMICIDIN A)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		3 / 3 ALA A  97
VAL A 122
TRP A 132
 None
 0.90A 1tkqB-5eo6A:
undetectable		 1tkqB-5eo6A:
9.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1YAJ_A_BEZA11_0
(CES1 PROTEIN)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		4 / 4 LEU A  27
SER A 114
LEU A 219
LEU A 223
 None
 0.99A 1yajA-5eo6A:
0.4		 1yajA-5eo6A:
19.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ACK_A_EDRA999_1
(ACETYLCHOLINESTERASE)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		4 / 7 TRP A 153
GLY A 137
PHE A 180
HIS A 115
 None
None
None
ACT  A 400 (-3.1A)
 1.09A 2ackA-5eo6A:
undetectable		 2ackA-5eo6A:
19.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QR2_B_VK3B235_1
(PROTEIN (QUINONE
REDUCTASE TYPE 2))		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		4 / 6 PHE A 195
PHE A 180
GLY A 259
ASN A 253
 None
None
None
ACT  A 400 (-3.1A)
 0.86A 2qr2A-5eo6A:
undetectable
2qr2B-5eo6A:
undetectable		 2qr2A-5eo6A:
20.12
2qr2B-5eo6A:
20.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3K_A_SAMA1254_0
(ESSENTIAL FOR
MITOTIC GROWTH 1)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		5 / 10 LEU A 199
PHE A 121
GLY A 136
ASP A 197
LEU A 120
 None
 0.93A 2v3kA-5eo6A:
undetectable		 2v3kA-5eo6A:
20.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_B_TFPB202_1
(PROTEIN S100-A4)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		3 / 3 GLU A  14
LEU A  17
ASP A  18
 None
 0.31A 3ko0A-5eo6A:
undetectable		 3ko0A-5eo6A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_S_TFPS202_2
(PROTEIN S100-A4)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		3 / 3 GLU A  14
LEU A  17
ASP A  18
 None
 0.19A 3ko0T-5eo6A:
undetectable		 3ko0T-5eo6A:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OYA_A_RLTA398_1
(PFV INTEGRASE)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		4 / 8 GLN A 242
PRO A 109
TYR A 144
PRO A 142
 None
 1.05A 3oyaA-5eo6A:
undetectable		 3oyaA-5eo6A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UNI_A_SALA1344_1
(XANTHINE
DEHYDROGENASE/OXIDAS
E)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		4 / 7 GLU A  28
THR A  62
VAL A  63
ALA A  38
 None
 0.84A 3uniA-5eo6A:
undetectable		 3uniA-5eo6A:
13.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B3Q_A_NVPA999_1
(REVERSE
TRANSCRIPTASE/RIBONU
CLEASE H)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		4 / 7 LEU A 219
VAL A  69
LEU A  27
TYR A 218
 None
 1.14A 4b3qA-5eo6A:
undetectable		 4b3qA-5eo6A:
18.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DRJ_A_RAPA201_2
(PEPTIDYL-PROLYL
CIS-TRANS ISOMERASE
FKBP4
SERINE/THREONINE-PRO
TEIN KINASE MTOR)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		4 / 8 LEU A  16
THR A   7
ASP A   8
PHE A  15
 None
 1.08A 4drjB-5eo6A:
undetectable		 4drjB-5eo6A:
15.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGJ_A_1PQA304_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		4 / 8 PHE A 195
PHE A 180
GLY A 259
ASN A 253
 None
None
None
ACT  A 400 (-3.1A)
 0.85A 4fgjA-5eo6A:
undetectable
4fgjB-5eo6A:
undetectable		 4fgjA-5eo6A:
20.37
4fgjB-5eo6A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4M6T_A_SAMA201_0
(RNA POLYMERASE
II-ASSOCIATED FACTOR
1 HOMOLOG, LINKER,
RNA
POLYMERASE-ASSOCIATE
D PROTEIN LEO1)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		4 / 4 ILE A  23
VAL A 103
VAL A  69
ARG A  56
 None
ACT  A 400 (-4.6A)
None
None
 1.32A 4m6tA-5eo6A:
undetectable		 4m6tA-5eo6A:
19.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		5 / 11 TYR A 252
GLY A 137
PHE A 195
GLY A 192
ASP A 257
 None
None
None
None
ACT  A 400 ( 4.2A)
 1.24A 4mm9A-5eo6A:
undetectable		 4mm9A-5eo6A:
22.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QOI_A_ML1A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		4 / 8 PHE A 195
PHE A 180
GLY A 259
ASN A 253
 None
None
None
ACT  A 400 (-3.1A)
 0.88A 4qoiA-5eo6A:
undetectable
4qoiB-5eo6A:
undetectable		 4qoiA-5eo6A:
20.37
4qoiB-5eo6A:
20.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		5 / 10 PHE A 164
GLY A 136
PHE A 138
ALA A 157
ALA A 213
 None
 1.33A 4wnuD-5eo6A:
undetectable		 4wnuD-5eo6A:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		3 / 3 ASP A 203
ASN A 200
PHE A 196
 None
 0.76A 5dsgB-5eo6A:
undetectable		 5dsgB-5eo6A:
21.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEO_A_VDYA206_1
(CDL2.3A)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		5 / 12 LEU A  58
LEU A 223
LEU A 219
PHE A  40
GLU A  31
 None
 1.29A 5ieoA-5eo6A:
1.4		 5ieoA-5eo6A:
17.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		4 / 5 PRO A 278
HIS A 115
LEU A 303
TYR A 256
 None
ACT  A 400 (-3.1A)
None
None
 1.36A 5igjA-5eo6A:
undetectable		 5igjA-5eo6A:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWV_A_ACAA18_2
(SCRFP-TAG,GP41)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		4 / 7 GLN A 148
LEU A 151
ALA A 157
LEU A 160
 None
 1.12A 5nwvA-5eo6A:
undetectable		 5nwvA-5eo6A:
7.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5U63_A_ACTA406_0
(THIOREDOXIN
REDUCTASE)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		3 / 3 HIS A 115
SER A 101
ARG A 119
 ACT  A 400 (-3.1A)
None
None
 0.90A 5u63A-5eo6A:
undetectable		 5u63A-5eo6A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_E_CHDE401_0
(BILE SALT HYDROLASE)		 5eo6 COPROPORPHYRINOGEN
OXIDASE
(Acinetobacter
baumannii) 		4 / 8 ILE A 225
LEU A 140
ALA A 116
LEU A 102
 None
 0.77A 5y7pE-5eo6A:
undetectable		 5y7pE-5eo6A:
20.82