SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eo7'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		4 / 7 TRP A 271
THR A 293
LEU A 278
LEU A  24
 None
SFU  A 405 ( 4.1A)
None
SFU  A 405 ( 4.1A)
 1.07A 1gtiD-5eo7A:
undetectable		 1gtiD-5eo7A:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HVY_D_D16D417_1
(THYMIDYLATE SYNTHASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		6 / 12 GLU A 275
TRP A 271
ASN A  19
LEU A  24
LEU A 278
ALA A 267
 None
None
None
SFU  A 405 ( 4.1A)
None
None
 1.40A 1hvyD-5eo7A:
undetectable		 1hvyD-5eo7A:
24.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_A_DVAA6_0
(GRAMICIDIN A)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		3 / 3 ALA A 191
VAL A 178
TRP A 179
 None
 0.89A 1nt5A-5eo7A:
undetectable		 1nt5A-5eo7A:
4.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1NT5_B_DVAB6_0
(GRAMICIDIN A)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		3 / 3 ALA A 191
VAL A 178
TRP A 179
 None
 0.89A 1nt5B-5eo7A:
undetectable		 1nt5B-5eo7A:
4.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P91_B_SAMB2401_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE A)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		5 / 12 TYR A 139
GLY A 162
TYR A 128
ILE A 112
THR A 132
 None
 1.12A 1p91B-5eo7A:
undetectable		 1p91B-5eo7A:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DCF_A_ACAA501_1
(6-AMINOHEXANOATE-DIM
ER HYDROLASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		4 / 6 ALA A 216
TRP A 179
ILE A 231
ILE A 268
 None
 1.28A 2dcfA-5eo7A:
undetectable		 2dcfA-5eo7A:
24.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HS1_A_017A201_2
(HIV-1 PROTEASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		5 / 12 LEU A 202
ILE A 205
ILE A 231
GLY A 162
ILE A 161
 None
 0.61A 2hs1B-5eo7A:
undetectable		 2hs1B-5eo7A:
17.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IYF_A_ERYA1400_0
(OLEANDOMYCIN
GLYCOSYLTRANSFERASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		5 / 11 ASN A 235
VAL A 234
ILE A 231
ALA A 216
ASP A 207
 None
 1.39A 2iyfA-5eo7A:
undetectable		 2iyfA-5eo7A:
22.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q83_B_ADNB2_1
(YTAA PROTEIN)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		4 / 6 ILE A 136
PRO A  61
LEU A  83
ILE A 112
 None
 0.95A 2q83B-5eo7A:
undetectable		 2q83B-5eo7A:
20.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V0Z_O_C41O1327_2
(RENIN)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		4 / 8 TYR A  40
SER A  66
THR A 218
LEU A 278
 SFU  A 405 (-3.1A)
None
None
None
 1.10A 2v0zO-5eo7A:
undetectable		 2v0zO-5eo7A:
20.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YVL_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		5 / 12 ILE A  15
ILE A 266
ALA A 267
ALA A 129
PHE A 180
 None
 1.05A 2yvlA-5eo7A:
undetectable		 2yvlA-5eo7A:
21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HGX_A_SALA102_1
(SALICYLATE
BIOSYNTHESIS PROTEIN
PCHB)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		4 / 7 VAL A 163
ILE A 127
TYR A 128
ILE A 112
 None
 1.04A 3hgxA-5eo7A:
undetectable		 3hgxA-5eo7A:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QL6_A_NIMA614_1
(LACTOPEROXIDASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		4 / 7 GLN A 249
HIS A 252
PHE A 220
PRO A 274
 None
None
SFU  A 404 ( 4.2A)
SFU  A 404 ( 4.2A)
 1.39A 3ql6A-5eo7A:
undetectable		 3ql6A-5eo7A:
20.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q1Y_A_017A106_2
(ASPARTYL PROTEASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		5 / 12 LEU A 202
ILE A 205
ILE A 231
GLY A 162
ILE A 161
 None
 0.67A 4q1yB-5eo7A:
undetectable		 4q1yB-5eo7A:
16.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R87_I_SPMI202_1
(SPERMIDINE
N1-ACETYLTRANSFERASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		4 / 7 ASN A  46
GLU A  37
TYR A  40
GLU A  41
 None
SFU  A 401 (-2.3A)
SFU  A 405 (-3.1A)
None
 1.22A 4r87I-5eo7A:
undetectable		 4r87I-5eo7A:
19.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E8Q_A_FOLA201_1
(DIHYDROFOLATE
REDUCTASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		3 / 3 ASP A 193
LEU A 152
ARG A 190
 None
 0.85A 5e8qA-5eo7A:
undetectable		 5e8qA-5eo7A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EQP_A_BUWA601_1
(CHOLINESTERASE)		 5eo7 PREDICTED PROTEIN
(Aspergillus
oryzae) 		4 / 8 GLY A   5
GLN A   7
THR A   3
PHE A  28
 None
 1.11A 6eqpA-5eo7A:
undetectable		 6eqpA-5eo7A:
17.09