SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eoc'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IEO_A_017A402_2
(PROTEASE)		 5eoc FAB FRAGMENT (HEAVY
CHAIN)
(Mus
musculus) 		5 / 12 LEU H 142
VAL H 167
GLY H 161
VAL H 187
VAL H 185
 None
 0.84A 2ieoB-5eocH:
undetectable		 2ieoB-5eocH:
19.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y03_A_5FWA601_1
(BETA-1 ADRENERGIC
RECEPTOR)		 5eoc FAB FRAGMENT (HEAVY
CHAIN)
(Mus
musculus) 		5 / 12 VAL H 167
VAL H 185
SER H 183
ASN H 200
ASN H 159
 None
 1.45A 2y03A-5eocH:
undetectable		 2y03A-5eocH:
20.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NYA_A_JTZA1203_1
(BETA-2 ADRENERGIC
RECEPTOR, LYSOZYME)		 5eoc FAB FRAGMENT (HEAVY
CHAIN)
(Mus
musculus) 		5 / 12 VAL H 167
VAL H 185
SER H 183
ASN H 200
ASN H 159
 None
 1.43A 3nyaA-5eocH:
undetectable		 3nyaA-5eocH:
16.73
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5MTH_A_ACTA302_0
(ANTIBODY FAB HEAVY
CHAIN)		 5eoc FAB FRAGMENT (HEAVY
CHAIN)
(Mus
musculus) 		4 / 5 SER H 118
ALA H 120
PHE H 150
LEU H 174
 None
 0.29A 5mthA-5eocH:
29.0		 5mthA-5eocH:
81.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6DWN_B_AQ4B602_1
(CYTOCHROME P450 1A1)		 5eoc FAB FRAGMENT (HEAVY
CHAIN)
(Mus
musculus) 		4 / 7 GLY H   8
ALA H   9
VAL H  18
LEU H  20
 None
 0.74A 6dwnB-5eocH:
undetectable		 6dwnB-5eocH:
16.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6FOS_B_PQNB2002_1
(PHOTOSYSTEM I P700
CHLOROPHYLL A
APOPROTEIN A2)		 5eoc FAB FRAGMENT (HEAVY
CHAIN)
(Mus
musculus) 		4 / 6 MET H  50
TRP H  47
LEU H 106
ALA H  97
 None
 1.20A 6fosB-5eocH:
undetectable		 6fosB-5eocH:
16.13