SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eod'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_A_DVAA8_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.71A 1a7yA-5eodA:
undetectable		 1a7yA-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB2_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 390
PRO A 392
THR A 393
 None
 0.70A 1a7yB-5eodA:
undetectable		 1a7yB-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A7Y_B_DVAB8_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.80A 1a7yB-5eodA:
undetectable		 1a7yB-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC2_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 390
PRO A 392
THR A 393
 None
 0.77A 1dscC-5eodA:
undetectable		 1dscC-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DSC_C_DVAC8_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.74A 1dscC-5eodA:
undetectable		 1dscC-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ETR_H_MITH1_1
(EPSILON-THROMBIN)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 12 HIS A 413
SER A 557
TRP A 577
GLY A 578
GLY A 588
 None
 0.80A 1etrH-5eodA:
27.5		 1etrH-5eodA:
17.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_C_DVAC8_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.66A 1fjaC-5eodA:
undetectable		 1fjaC-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1FJA_D_DVAD8_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.66A 1fjaD-5eodA:
undetectable		 1fjaD-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GSE_B_EAAB224_1
(GLUTATHIONE
TRANSFERASE)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 12 GLY A 558
LEU A 397
LEU A 466
ALA A 464
PHE A 415
 None
 1.09A 1gseB-5eodA:
undetectable		 1gseB-5eodA:
16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE2_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 390
PRO A 392
THR A 393
 None
 0.68A 1i3wE-5eodA:
undetectable		 1i3wE-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_E_DVAE8_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.79A 1i3wE-5eodA:
undetectable		 1i3wE-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_F_DVAF8_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.67A 1i3wF-5eodA:
undetectable		 1i3wF-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG2_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 390
PRO A 392
THR A 393
 None
 0.76A 1i3wG-5eodA:
undetectable		 1i3wG-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_G_DVAG8_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.70A 1i3wG-5eodA:
undetectable		 1i3wG-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1I3W_H_DVAH8_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.71A 1i3wH-5eodA:
undetectable		 1i3wH-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJO_C_SAMC200_0
(METHIONINE REPRESSOR)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 12 ALA A 205
PHE A 206
GLY A 209
LEU A 257
PRO A 188
 None
 1.28A 1mjoC-5eodA:
undetectable
1mjoD-5eodA:
undetectable		 1mjoC-5eodA:
11.01
1mjoD-5eodA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_C_SAMC199_0
(METHIONINE REPRESSOR)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 10 LEU A 257
PRO A 188
ALA A 205
PHE A 206
GLY A 209
 None
 1.35A 1mjqC-5eodA:
undetectable
1mjqD-5eodA:
undetectable		 1mjqC-5eodA:
11.01
1mjqD-5eodA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MJQ_I_SAMI199_0
(METHIONINE REPRESSOR)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 11 LEU A 257
PRO A 188
ALA A 205
PHE A 206
GLY A 209
 None
 1.34A 1mjqI-5eodA:
undetectable
1mjqJ-5eodA:
undetectable		 1mjqI-5eodA:
11.01
1mjqJ-5eodA:
11.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD2_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 390
PRO A 392
THR A 393
 None
 0.75A 1mnvD-5eodA:
undetectable		 1mnvD-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MNV_D_DVAD8_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.69A 1mnvD-5eodA:
undetectable		 1mnvD-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OVF_B_DVAB2_0
(ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 390
PRO A 392
THR A 393
 None
 0.65A 1ovfB-5eodA:
undetectable		 1ovfB-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_A_DVAA8_0
(ACTINOMYCIN X2)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.71A 1qfiA-5eodA:
undetectable		 1qfiA-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1QFI_B_DVAB8_0
(ACTINOMYCIN X2)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.83A 1qfiB-5eodA:
undetectable		 1qfiB-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_F_DVAF8_0
(7-AMINO-ACTINOMYCIN
D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.73A 1unjF-5eodA:
undetectable		 1unjF-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL2_0
(7-AMINO-ACTINOMYCIN
D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 390
PRO A 392
THR A 393
 None
 0.77A 1unjL-5eodA:
undetectable		 1unjL-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_L_DVAL8_0
(7-AMINO-ACTINOMYCIN
D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.72A 1unjL-5eodA:
undetectable		 1unjL-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR2_0
(7-AMINO-ACTINOMYCIN
D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 390
PRO A 392
THR A 393
 None
 0.79A 1unjR-5eodA:
undetectable		 1unjR-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_R_DVAR8_0
(7-AMINO-ACTINOMYCIN
D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.70A 1unjR-5eodA:
undetectable		 1unjR-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_W_DVAW8_0
(7-AMINO-ACTINOMYCIN
D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.78A 1unjW-5eodA:
undetectable		 1unjW-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX2_0
(7-AMINO-ACTINOMYCIN
D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 390
PRO A 392
THR A 393
 None
 0.76A 1unjX-5eodA:
undetectable		 1unjX-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNJ_X_DVAX8_0
(7-AMINO-ACTINOMYCIN
D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.72A 1unjX-5eodA:
undetectable		 1unjX-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE2_0
(7-AMINOACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 390
PRO A 392
THR A 393
 None
 0.82A 1unmE-5eodA:
undetectable		 1unmE-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_E_DVAE8_0
(7-AMINOACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.71A 1unmE-5eodA:
undetectable		 1unmE-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF2_0
(7-AMINOACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 390
PRO A 392
THR A 393
 None
 0.64A 1unmF-5eodA:
undetectable		 1unmF-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UNM_F_DVAF8_0
(7-AMINOACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.65A 1unmF-5eodA:
undetectable		 1unmF-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
209D_C_DVAC8_0
(N8-ACTINOMYCIN D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 393
THR A 390
PRO A 392
 None
 0.73A 209dC-5eodA:
undetectable		 209dC-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2IGT_C_SAMC1003_0
(SAM DEPENDENT
METHYLTRANSFERASE)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 12 PHE A 415
TYR A 416
ALA A 411
ALA A 464
GLY A 558
 None
 1.19A 2igtC-5eodA:
undetectable		 2igtC-5eodA:
20.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P16_A_GG2A298_1
(COAGULATION FACTOR X
(EC 3.4.21.6)
(STUART FACTOR)
(STUART-PROWER
FACTOR))		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 12 SER A 557
TRP A 577
GLY A 578
GLY A 588
TYR A 590
 None
 0.84A 2p16A-5eodA:
27.5		 2p16A-5eodA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2W26_A_RIVA1001_1
(ACTIVATED FACTOR XA
HEAVY CHAIN)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 12 SER A 557
TRP A 577
GLY A 578
GLY A 588
TYR A 590
 None
 0.74A 2w26A-5eodA:
27.5		 2w26A-5eodA:
15.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2XCT_H_CPFH1020_1
(DNA GYRASE SUBUNIT
B, DNA GYRASE
SUBUNIT A)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 ARG A 234
GLU A 231
SER A 349
 None
 0.80A 2xctD-5eodA:
undetectable		 2xctD-5eodA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
316D_C_DVAC2_0
(8-FLUORO-ACTINOMYCIN
D)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 THR A 390
PRO A 392
THR A 393
 None
 0.91A 316dC-5eodA:
undetectable		 316dC-5eodA:
1.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCJ_A_THHA401_0
(PROBABLE
5'-PHOSPHORIBOSYLGLY
CINAMIDE
FORMYLTRANSFERASE
PURN)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 12 LEU A 466
LEU A 468
THR A 499
VAL A 426
PRO A 560
 None
 1.25A 3dcjA-5eodA:
undetectable
3dcjB-5eodA:
undetectable		 3dcjA-5eodA:
16.03
3dcjB-5eodA:
16.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EEO_A_SAMA328_0
(MODIFICATION
METHYLASE HHAI)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 12 LEU A 239
GLY A 217
ASP A 185
ILE A 183
PRO A 247
 None
 1.23A 3eeoA-5eodA:
undetectable		 3eeoA-5eodA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3GY3_A_PNTA246_0
(CATIONIC TRYPSIN)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 11 HIS A 413
SER A 557
TRP A 577
GLY A 578
GLY A 588
 None
 0.74A 3gy3A-5eodA:
24.8		 3gy3A-5eodA:
20.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IB0_A_DIFA701_1
(LACTOTRANSFERRIN)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		4 / 4 PRO A 316
TYR A 314
GLY A 347
THR A 281
 None
 1.11A 3ib0A-5eodA:
undetectable		 3ib0A-5eodA:
18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K2H_B_LYAB514_2
(DIHYDROFOLATE
REDUCTASE/THYMIDYLAT
E SYNTHASE)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 ARG A 378
THR A 440
THR A 513
 None
 0.69A 3k2hB-5eodA:
undetectable		 3k2hB-5eodA:
21.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KPD_B_SAMB1000_1
(UNCHARACTERIZED
PROTEIN MJ0100)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 ASN A 473
ASN A 405
GLU A 361
 None
 0.91A 3kpdC-5eodA:
undetectable		 3kpdC-5eodA:
14.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ME6_D_CGED501_1
(CYTOCHROME P450 2B4)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 9 VAL A 472
ILE A 402
THR A 410
VAL A 426
VAL A 385
 None
 1.25A 3me6D-5eodA:
undetectable		 3me6D-5eodA:
22.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ACB_C_DXCC1475_0
(TRANSLATION
ELONGATION FACTOR
SELB)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		4 / 8 ILE A 463
ASP A 462
ILE A 574
GLY A 400
 None
 0.79A 4acbC-5eodA:
2.2		 4acbC-5eodA:
22.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BBO_B_ACTB1114_0
(BLR5658 PROTEIN)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 TRP A 497
TRP A 381
THR A 499
 None
 1.36A 4bboB-5eodA:
undetectable		 4bboB-5eodA:
11.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4DUB_A_LDPA501_1
(CYTOCHROME P450 BM3
VARIANT 9D7)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		4 / 6 PHE A 415
ALA A 464
GLY A 400
LEU A 466
 None
 0.73A 4dubA-5eodA:
undetectable		 4dubA-5eodA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 5 GLY A 326
GLY A 324
GLU A 323
 None
 0.46A 4z2eA-5eodA:
undetectable
4z2eD-5eodA:
undetectable		 4z2eA-5eodA:
23.04
4z2eD-5eodA:
16.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5O96_B_SAMB501_0
(RIBOSOMAL RNA SMALL
SUBUNIT
METHYLTRANSFERASE E)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 9 LEU A 409
GLY A 558
GLY A 399
LEU A 465
ALA A 464
 None
 0.97A 5o96A-5eodA:
undetectable
5o96B-5eodA:
undetectable		 5o96A-5eodA:
17.11
5o96B-5eodA:
17.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OS7_A_ACTA402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 HIS A 129
SER A 171
LYS A 173
 None
 1.12A 5os7A-5eodA:
undetectable		 5os7A-5eodA:
18.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZNI_A_YMZA302_0
(PURINE NUCLEOSIDE
PHOSPHORYLASE)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		5 / 9 VAL A 572
GLY A 544
TYR A 590
VAL A 522
PRO A 587
 None
 1.39A 5zniA-5eodA:
undetectable		 5zniA-5eodA:
8.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GMD_B_ACTB402_0
(CASEIN KINASE II
SUBUNIT ALPHA)		 5eod COAGULATION FACTOR
XI
(Homo
sapiens) 		3 / 3 HIS A 129
SER A 171
LYS A 173
 None
 1.12A 6gmdB-5eodA:
undetectable		 6gmdB-5eodA:
18.58