SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eoe'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GHM_A_CEDA1_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
6 / 12 SER A  62
LYS A  65
SER A 123
ASN A 125
LYS A 227
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-3.6A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
0.26A 1ghmA-5eoeA:
36.3
1ghmA-5eoeA:
30.60
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_A_CFXA1300_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
8 / 12 SER A  62
LYS A  65
SER A 123
ASN A 125
GLU A 159
THR A 209
LYS A 227
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-3.6A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
0.33A 1i2wA-5eoeA:
39.0
1i2wA-5eoeA:
37.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_A_CFXA1300_2
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
4 / 5 TYR A  97
PRO A 160
LEU A 162
THR A 228
CIT  A 303 (-4.1A)
None
None
CIT  A 303 (-3.6A)
0.55A 1i2wA-5eoeA:
39.1
1i2wA-5eoeA:
37.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1I2W_B_CFXB2300_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 SER A  62
LYS A  65
SER A 123
ASN A 125
GLU A 159
THR A 209
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-3.6A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
0.34A 1i2wB-5eoeA:
39.0
1i2wB-5eoeA:
37.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_A_CFXA1001_1
(BETA-LACTAMASE
CTX-M-9)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
9 / 12 SER A  62
LYS A  65
SER A 123
ASN A 125
GLU A 159
ASN A 163
THR A 209
LYS A 227
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-3.6A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
0.40A 1ymxA-5eoeA:
40.6
1ymxA-5eoeA:
41.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_A_CFXA1001_2
(BETA-LACTAMASE
CTX-M-9)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
4 / 5 TYR A  97
PRO A 160
THR A 228
SER A 230
CIT  A 303 (-4.1A)
None
CIT  A 303 (-3.6A)
CIT  A 303 (-2.5A)
0.52A 1ymxA-5eoeA:
40.6
1ymxA-5eoeA:
41.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_1
(BETA-LACTAMASE
CTX-M-9)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
9 / 12 SER A  62
LYS A  65
SER A 123
ASN A 125
GLU A 159
ASN A 163
LYS A 227
GLY A 229
SER A 230
CIT  A 303 (-2.8A)
CIT  A 303 (-3.6A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
CIT  A 303 (-2.5A)
0.43A 1ymxB-5eoeA:
40.7
1ymxB-5eoeA:
41.79
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1YMX_B_CFXB1002_2
(BETA-LACTAMASE
CTX-M-9)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
4 / 5 TYR A  97
PRO A 160
THR A 209
THR A 228
CIT  A 303 (-4.1A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.6A)
0.39A 1ymxB-5eoeA:
40.7
1ymxB-5eoeA:
41.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G70_B_SAMB2002_0
(PHENYLETHANOLAMINE
N-METHYLTRANSFERASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
5 / 12 LEU A 200
VAL A 112
ALA A  78
VAL A  72
TYR A 144
None
1.44A 2g70B-5eoeA:
undetectable
2g70B-5eoeA:
21.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QBN_A_CAMA442_0
(CYTOCHROME P450-CAM)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
4 / 7 TYR A 255
THR A 174
VAL A  42
VAL A 251
None
1.03A 2qbnA-5eoeA:
undetectable
2qbnA-5eoeA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_D_ASDD1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
5 / 9 PRO A 138
LEU A 155
LEU A 132
ALA A 128
PHE A  64
None
1.15A 2vcvD-5eoeA:
undetectable
2vcvD-5eoeA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_E_ASDE1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
5 / 9 PRO A 138
LEU A 155
LEU A 132
ALA A 128
PHE A  64
None
1.12A 2vcvE-5eoeA:
undetectable
2vcvE-5eoeA:
21.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_H_ASDH1224_1
(GLUTATHIONE
S-TRANSFERASE A3)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
5 / 9 PRO A 138
LEU A 155
LEU A 132
ALA A 128
PHE A  64
None
1.11A 2vcvH-5eoeA:
undetectable
2vcvH-5eoeA:
21.90
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_A_CE3A301_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
9 / 12 LYS A  65
TYR A  97
SER A 123
ASN A 125
ASN A 163
THR A 209
LYS A 227
GLY A 229
SER A 230
CIT  A 303 (-3.6A)
CIT  A 303 (-4.1A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
CIT  A 303 (-2.5A)
0.54A 3hlwA-5eoeA:
40.5
3hlwA-5eoeA:
41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
6 / 12 THR A 209
LYS A 227
THR A 228
GLY A 229
SER A 230
GLY A 235
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
CIT  A 303 (-2.5A)
None
1.21A 3hlwB-5eoeA:
40.5
3hlwB-5eoeA:
41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HLW_B_CE3B302_1
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
9 / 12 TYR A  97
SER A 123
ASN A 125
ASN A 163
THR A 209
LYS A 227
THR A 228
GLY A 229
SER A 230
CIT  A 303 (-4.1A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
CIT  A 303 (-2.5A)
0.49A 3hlwB-5eoeA:
40.5
3hlwB-5eoeA:
41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_A_PNNA300_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 LYS A  65
ASN A 125
ASN A 163
LYS A 227
THR A 228
GLY A 229
SER A 230
CIT  A 303 (-3.6A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
CIT  A 303 (-2.5A)
0.37A 3huoA-5eoeA:
40.7
3huoA-5eoeA:
41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HUO_B_PNNB301_0
(CTX-M-9
EXTENDED-SPECTRUM
BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
6 / 12 LYS A  65
ASN A 125
ASN A 163
LYS A 227
GLY A 229
SER A 230
CIT  A 303 (-3.6A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
CIT  A 303 (-2.5A)
0.34A 3huoB-5eoeA:
40.7
3huoB-5eoeA:
41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3NY4_A_SMXA308_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 SER A  62
SER A 123
ASN A 163
THR A 209
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.50A 3ny4A-5eoeA:
39.1
3ny4A-5eoeA:
39.19
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
8 / 12 LYS A  65
SER A 123
ASN A 125
THR A 161
ASN A 163
LYS A 227
GLY A 229
SER A 230
CIT  A 303 (-3.6A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
CIT  A 303 (-2.5A)
0.43A 3q07A-5eoeA:
40.7
3q07A-5eoeA:
41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_A_WPPA300_2
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
4 / 5 TYR A  97
PRO A 160
THR A 164
THR A 228
CIT  A 303 (-4.1A)
None
None
CIT  A 303 (-3.6A)
0.37A 3q07A-5eoeA:
40.7
3q07A-5eoeA:
41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
8 / 12 LYS A  65
SER A 123
ASN A 125
THR A 161
ASN A 163
LYS A 227
GLY A 229
SER A 230
CIT  A 303 (-3.6A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
CIT  A 303 (-2.5A)
0.44A 3q07B-5eoeA:
40.7
3q07B-5eoeA:
41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3Q07_B_WPPB400_2
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
4 / 5 TYR A  97
PRO A 160
THR A 164
THR A 228
CIT  A 303 (-4.1A)
None
None
CIT  A 303 (-3.6A)
0.35A 3q07B-5eoeA:
40.7
3q07B-5eoeA:
41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_A_CEDA1_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 SER A  62
TYR A  97
SER A 123
ASN A 125
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-4.1A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.42A 3sh8A-5eoeA:
37.9
3sh8A-5eoeA:
35.53
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3SH8_B_CEDB1_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
6 / 12 SER A  62
LYS A  65
SER A 123
ASN A 125
LYS A 227
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-3.6A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
0.28A 3sh8B-5eoeA:
37.4
3sh8B-5eoeA:
35.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AX8_A_SAMA1474_0
(WBDD)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
5 / 12 GLY A  51
ILE A  26
SER A 253
VAL A  39
ILE A  37
None
0.99A 4ax8A-5eoeA:
undetectable
4ax8A-5eoeA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZS_A_SAMA1475_0
(METHYLTRANSFERASE
WBDD)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
5 / 12 GLY A  51
ILE A  26
GLU A  30
LEU A  41
VAL A  39
None
1.03A 4azsA-5eoeA:
undetectable
4azsA-5eoeA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
6 / 12 GLY A  51
ILE A  26
GLU A  30
LEU A  41
VAL A  39
ILE A  37
None
1.03A 4aztA-5eoeA:
undetectable
4aztA-5eoeA:
19.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZW_A_SAMA1451_0
(WBDD)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
5 / 12 GLY A  51
ILE A  26
GLU A  30
LEU A  41
VAL A  39
None
0.97A 4azwA-5eoeA:
undetectable
4azwA-5eoeA:
21.94
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4EUZ_A_MEMA401_1
(CARBAPENEM-HYDROLIZI
NG BETA-LACTAMASE
SFC-1)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
8 / 12 LYS A  65
SER A 123
ASN A 125
ASN A 163
THR A 209
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-3.6A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.36A 4euzA-5eoeA:
39.5
4euzA-5eoeA:
40.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4FH2_A_0RNA303_1
(BETA-LACTAMASE SHV-1)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
6 / 10 TYR A  97
SER A 123
ASN A 125
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-4.1A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.50A 4fh2A-5eoeA:
38.0
4fh2A-5eoeA:
37.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_A_MTLA804_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
4 / 6 ARG A 154
ASP A 169
ASP A 156
ARG A 171
None
1.41A 4kcnA-5eoeA:
undetectable
4kcnA-5eoeA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCN_B_MTLB805_0
(NITRIC OXIDE
SYNTHASE, BRAIN)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
4 / 6 ARG A 154
ASP A 169
ASP A 156
ARG A 171
None
1.39A 4kcnB-5eoeA:
undetectable
4kcnB-5eoeA:
21.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
4 / 8 TYR A 255
THR A 174
VAL A  42
VAL A 251
None
0.97A 4l4bA-5eoeA:
undetectable
4l4bA-5eoeA:
21.41
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_A_CEDA301_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
8 / 12 SER A  62
TYR A  97
SER A 123
ASN A 125
ASN A 163
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-4.1A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.31A 4n9kA-5eoeA:
39.3
4n9kA-5eoeA:
36.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4N9K_B_CEDB301_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 SER A  62
SER A 123
ASN A 125
ASN A 163
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.23A 4n9kB-5eoeA:
39.4
4n9kB-5eoeA:
36.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
6 / 12 THR A 209
LYS A 227
THR A 228
GLY A 229
SER A 230
GLY A 235
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
CIT  A 303 (-2.5A)
None
1.23A 4pm5A-5eoeA:
40.7
4pm5A-5eoeA:
41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
8 / 12 TYR A  97
ASN A 125
ASN A 163
THR A 209
LYS A 227
THR A 228
GLY A 229
SER A 230
CIT  A 303 (-4.1A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
CIT  A 303 (-2.5A)
0.52A 4pm5A-5eoeA:
40.7
4pm5A-5eoeA:
41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM5_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
8 / 12 TYR A  97
SER A 123
ASN A 125
ASN A 163
LYS A 227
THR A 228
GLY A 229
SER A 230
CIT  A 303 (-4.1A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
CIT  A 303 (-2.5A)
0.71A 4pm5A-5eoeA:
40.7
4pm5A-5eoeA:
41.42
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 LYS A  65
TYR A  97
ASN A 125
ASN A 163
THR A 209
LYS A 227
GLY A 229
CIT  A 303 (-3.6A)
CIT  A 303 (-4.1A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
0.54A 4pm7A-5eoeA:
40.7
4pm7A-5eoeA:
41.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM7_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 LYS A  65
TYR A  97
SER A 123
ASN A 125
ASN A 163
LYS A 227
GLY A 229
CIT  A 303 (-3.6A)
CIT  A 303 (-4.1A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
0.75A 4pm7A-5eoeA:
40.7
4pm7A-5eoeA:
41.04
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 TYR A  97
ASN A 125
ASN A 163
THR A 209
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-4.1A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.43A 4pm9A-5eoeA:
40.7
4pm9A-5eoeA:
41.57
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4PM9_A_CE3A301_1
(BETA-LACTAMASE
CTX-M-14)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 TYR A  97
SER A 123
ASN A 125
ASN A 163
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-4.1A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.65A 4pm9A-5eoeA:
40.7
4pm9A-5eoeA:
41.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
5 / 12 GLY A  51
ILE A  26
GLU A  30
LEU A  41
VAL A  39
None
1.05A 4uw0A-5eoeA:
undetectable
4uw0A-5eoeA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UW0_A_SAMA1506_0
(WBDD)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
5 / 12 GLY A  51
ILE A  26
LEU A  41
VAL A  39
ILE A  37
None
0.99A 4uw0A-5eoeA:
undetectable
4uw0A-5eoeA:
19.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WNU_D_QDND602_1
(CYTOCHROME P450 2D6)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
5 / 10 GLY A 108
LEU A  94
ALA A 126
ASP A 124
ALA A 115
None
1.26A 4wnuD-5eoeA:
undetectable
4wnuD-5eoeA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DSG_B_0HKB1201_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M4,ENDOLYSIN,ENDOLYS
IN,MUSCARINIC
ACETYLCHOLINE
RECEPTOR M4)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
3 / 3 ASP A 226
ASN A 237
PHE A  64
None
0.74A 5dsgB-5eoeA:
undetectable
5dsgB-5eoeA:
19.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_C_RAPC999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
4 / 8 SER A 184
PHE A 188
GLY A 189
TYR A 250
None
0.96A 5flcB-5eoeA:
undetectable
5flcB-5eoeA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FLC_G_RAPG999_1
(SERINE/THREONINE-PRO
TEIN KINASE MTOR
FKBP)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
4 / 8 SER A 184
PHE A 188
GLY A 189
TYR A 250
None
0.97A 5flcF-5eoeA:
undetectable
5flcF-5eoeA:
13.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5G5G_A_ACTA1231_0
(PUTATIVE XANTHINE
DEHYDROGENASE YAGR
MOLYBDENUM-BINDING
SU SUBUNIT
PUTATIVE XANTHINE
DEHYDROGENASE YAGT
IRON-SULFUR-BINDING
SUBUNIT)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
3 / 3 ARG A 157
THR A 166
ASP A 169
None
0.81A 5g5gA-5eoeA:
undetectable
5g5gB-5eoeA:
undetectable
5g5gA-5eoeA:
22.10
5g5gB-5eoeA:
23.39
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_A_CEDA301_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
6 / 12 SER A  62
SER A 123
ASN A 125
ASN A 163
LYS A 227
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
0.24A 5ghyA-5eoeA:
39.0
5ghyA-5eoeA:
36.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHY_B_CEDB301_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
6 / 12 SER A  62
SER A 123
ASN A 125
ASN A 163
LYS A 227
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
0.22A 5ghyB-5eoeA:
39.3
5ghyB-5eoeA:
36.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_A_CEDA301_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
8 / 11 SER A  62
TYR A  97
SER A 123
ASN A 125
ASN A 163
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-4.1A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.35A 5ghzA-5eoeA:
39.2
5ghzA-5eoeA:
36.67
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5GHZ_B_CEDB301_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
8 / 10 SER A  62
TYR A  97
SER A 123
ASN A 125
ASN A 163
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-4.1A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.34A 5ghzB-5eoeA:
39.4
5ghzB-5eoeA:
36.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HFJ_H_SAMH301_0
(ADENINE SPECIFIC DNA
METHYLTRANSFERASE
(DPNA))
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
5 / 12 ASP A 124
ALA A 128
PRO A 160
THR A 164
THR A 173
None
1.29A 5hfjH-5eoeA:
undetectable
5hfjH-5eoeA:
22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1O_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
3 / 3 ALA A 126
ASN A 129
LEU A 130
None
0.35A 5i1oC-5eoeA:
undetectable
5i1oC-5eoeA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5I1P_F_DVAF9_0
(D-VILLIN HEADPIECE
SUBDOMAIN
VILLIN-1)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
3 / 3 ALA A 126
ASN A 129
LEU A 130
None
0.36A 5i1pA-5eoeA:
undetectable
5i1pA-5eoeA:
10.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UXC_A_ZITA306_1
(PREDICTED
AMINOGLYCOSIDE
PHOSPHOTRANSFERASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
4 / 7 THR A 142
PHE A  64
ASP A 172
LEU A 162
None
1.20A 5uxcA-5eoeA:
undetectable
5uxcA-5eoeA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y7P_H_CHDH401_0
(BILE SALT HYDROLASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
5 / 10 LEU A  87
ILE A  76
LEU A  73
LEU A 120
ALA A 119
None
1.14A 5y7pH-5eoeA:
undetectable
5y7pH-5eoeA:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5YVN_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
4 / 6 LEU A 162
LYS A  65
LEU A  68
LEU A 132
None
CIT  A 303 (-3.6A)
None
None
1.10A 5yvnA-5eoeA:
undetectable
5yvnA-5eoeA:
20.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_B_9F2B400_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 SER A  62
SER A 123
ASN A 163
THR A 209
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.42A 6b5yB-5eoeA:
39.4
6b5yB-5eoeA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B5Y_D_9F2D400_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 SER A  62
SER A 123
ASN A 163
THR A 209
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.45A 6b5yD-5eoeA:
39.4
6b5yD-5eoeA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_B_9F2B301_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 SER A  62
SER A 123
ASN A 163
THR A 209
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.31A 6b68B-5eoeA:
39.5
6b68B-5eoeA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B68_D_9F2D400_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
6 / 12 SER A  62
SER A 123
ASN A 163
THR A 209
LYS A 227
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
0.38A 6b68D-5eoeA:
39.4
6b68D-5eoeA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_B_9F2B301_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
8 / 12 SER A  62
SER A 123
PRO A 160
ASN A 163
THR A 209
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
None
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.31A 6b69A-5eoeA:
39.4
6b69B-5eoeA:
39.4
6b69A-5eoeA:
16.08
6b69B-5eoeA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B69_D_9F2D301_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 SER A  62
SER A 123
ASN A 163
THR A 209
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.32A 6b69D-5eoeA:
39.3
6b69D-5eoeA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_B_9F2B301_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 SER A  62
SER A 123
ASN A 163
THR A 209
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.35A 6b6aB-5eoeA:
39.3
6b6aB-5eoeA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6A_D_9F2D301_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
6 / 12 SER A  62
SER A 123
ASN A 163
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.32A 6b6aD-5eoeA:
39.0
6b6aD-5eoeA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6C_A_9F2A301_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 SER A  62
SER A 123
PRO A 160
ASN A 163
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
None
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.40A 6b6cA-5eoeA:
39.1
6b6cA-5eoeA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6D_A_9F2A302_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 SER A  62
SER A 123
ASN A 163
THR A 209
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.57A 6b6dA-5eoeA:
39.0
6b6dA-5eoeA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6E_A_9F2A302_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
7 / 12 SER A  62
SER A 123
ASN A 163
THR A 209
LYS A 227
THR A 228
GLY A 229
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.34A 6b6eA-5eoeA:
39.1
6b6eA-5eoeA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6B6F_A_9F2A301_1
(BETA-LACTAMASE)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
8 / 12 CSS A  61
SER A  62
SER A 123
PRO A 160
ASN A 163
LYS A 227
THR A 228
GLY A 229
None
CIT  A 303 (-2.8A)
CIT  A 303 (-2.5A)
None
None
CIT  A 303 (-3.5A)
CIT  A 303 (-3.6A)
CIT  A 303 (-3.5A)
0.52A 6b6fA-5eoeA:
38.8
6b6fA-5eoeA:
16.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)
5eoe BETA-LACTAMASE
(Pseudomonas
aeruginosa)
8 / 12 TYR A  97
SER A 123
ASN A 125
ASN A 163
THR A 209
LYS A 227
GLY A 229
SER A 230
CIT  A 303 (-4.1A)
CIT  A 303 (-2.5A)
CIT  A 303 (-3.2A)
None
CIT  A 303 (-3.2A)
CIT  A 303 (-3.5A)
CIT  A 303 (-3.5A)
CIT  A 303 (-2.5A)
0.52A 6c79A-5eoeA:
40.8
6c79A-5eoeA:
17.50