SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5eog'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7A_B_PFLB4001_1
(SERUM ALBUMIN)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		5 / 9 LEU A 257
ILE A 253
LEU A 350
GLY A 297
LEU A 356
 None
 1.19A 1e7aB-5eogA:
undetectable		 1e7aB-5eogA:
20.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1PCG_A_ESTA1_1
(ESTROGEN RECEPTOR)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		5 / 10 LEU A 269
LEU A 254
LEU A 277
ILE A 308
LEU A 345
 None
 1.30A 1pcgA-5eogA:
undetectable		 1pcgA-5eogA:
18.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		5 / 12 ALA A 346
LEU A 345
LEU A 304
GLY A 297
LEU A   8
 None
 1.11A 2jfaB-5eogA:
undetectable		 2jfaB-5eogA:
20.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VCV_P_ASDP1224_1
(GLUTATHIONE
S-TRANSFERASE A3)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		4 / 8 LEU A 321
LEU A 324
LEU A  94
ALA A 229
 None
 0.80A 2vcvP-5eogA:
undetectable		 2vcvP-5eogA:
22.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_B_SVRB512_1
(PHOSPHOLIPASE A2)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		4 / 5 VAL A 167
VAL A 168
THR A 155
THR A  72
 None
 1.18A 3bjwA-5eogA:
undetectable		 3bjwA-5eogA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_E_SVRE510_3
(PHOSPHOLIPASE A2)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		4 / 5 VAL A 167
VAL A 168
THR A 155
THR A  72
 None
 1.12A 3bjwG-5eogA:
undetectable		 3bjwG-5eogA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_F_SVRF509_1
(PHOSPHOLIPASE A2)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		4 / 5 VAL A 167
VAL A 168
THR A 155
THR A  72
 None
 1.15A 3bjwC-5eogA:
undetectable		 3bjwC-5eogA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BJW_H_SVRH511_2
(PHOSPHOLIPASE A2)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		4 / 5 VAL A 167
VAL A 168
THR A 155
THR A  72
 None
 1.18A 3bjwD-5eogA:
undetectable		 3bjwD-5eogA:
14.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3THR_C_C2FC1410_0
(GLYCINE
N-METHYLTRANSFERASE)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		3 / 3 ARG A 314
PRO A 268
PHE A 327
 None
 0.97A 3thrC-5eogA:
undetectable		 3thrC-5eogA:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K50_A_ACTA505_0
(RNA POLYMERASE
3D-POL)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		3 / 3 CYH A  20
ASN A  17
LYS A 249
 None
 1.15A 4k50A-5eogA:
undetectable		 4k50A-5eogA:
19.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XJ7_A_ADNA303_1
(5'/3'-NUCLEOTIDASE
SURE)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		5 / 10 GLY A 297
ILE A 253
LEU A  12
LEU A 300
TYR A  15
 None
 1.17A 4xj7A-5eogA:
undetectable
4xj7B-5eogA:
undetectable		 4xj7A-5eogA:
20.98
4xj7B-5eogA:
20.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ESG_A_1YNA701_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		5 / 12 GLU A  75
PHE A  86
ILE A 117
PHE A 174
VAL A 231
 None
 1.19A 5esgA-5eogA:
undetectable		 5esgA-5eogA:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EU8_B_010B6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		4 / 5 LEU A 307
HIS A 273
THR A 276
CYH A 310
 None
 1.05A 5eu8A-5eogA:
undetectable		 5eu8A-5eogA:
20.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IEP_A_VDYA201_2
(CDL2.3B)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		5 / 9 ILE A 192
PRO A 286
VAL A 203
LEU A 241
TYR A 280
 None
 1.49A 5iepA-5eogA:
undetectable		 5iepA-5eogA:
16.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5TWJ_A_SAMA201_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE H)		 5eog PROTEIN MAB-21-LIKE
1
(Homo
sapiens) 		5 / 12 ILE A 303
GLY A 297
SER A 252
LEU A 251
VAL A 278
 None
 0.88A 5twjA-5eogA:
undetectable		 5twjA-5eogA:
18.11