SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ep0'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JN3_A_JN3A130_1
(FATTY ACID-BINDING
PROTEIN, LIVER)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		5 / 12 LEU A  55
LEU A  66
ALA A  93
ILE A  94
GLN A  99
 None
 1.06A 2jn3A-5ep0A:
undetectable		 2jn3A-5ep0A:
16.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2N27_A_4DYA205_1
(CALMODULIN)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		5 / 11 ILE A 323
MET A 149
LEU A  50
VAL A  79
MET A  81
 None
 1.28A 2n27A-5ep0A:
undetectable		 2n27A-5ep0A:
18.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		5 / 11 ARG A 277
ILE A 168
ALA A 182
ALA A 180
VAL A 279
 None
 1.20A 2qhfA-5ep0A:
undetectable		 2qhfA-5ep0A:
24.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		5 / 10 GLU A  92
ARG A  95
ILE A  94
GLY A  97
ILE A  80
 None
 1.22A 3adsA-5ep0A:
undetectable		 3adsA-5ep0A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ADS_A_IMNA1_1
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		5 / 10 GLU A  92
ILE A  94
GLY A  97
LEU A  50
ILE A  80
 None
 1.15A 3adsA-5ep0A:
undetectable		 3adsA-5ep0A:
20.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G1U_C_ADNC438_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		5 / 12 GLU A 177
ASP A 241
LEU A 310
MET A 239
PHE A 194
 None
SO4  A 401 ( 4.6A)
None
None
None
 1.27A 3g1uC-5ep0A:
6.8		 3g1uC-5ep0A:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T44A501_1
(THYROID HORMONE
RECEPTOR ALPHA)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		4 / 6 SER A 187
VAL A 166
THR A 165
ARG A 277
 None
 1.19A 4lnxA-5ep0A:
undetectable		 4lnxA-5ep0A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PFJ_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		5 / 12 GLU A 177
ASP A 241
LEU A 310
MET A 239
PHE A 194
 None
SO4  A 401 ( 4.6A)
None
None
None
 1.28A 4pfjB-5ep0A:
6.5		 4pfjB-5ep0A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_A_ADNA502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		5 / 12 GLU A 177
ASP A 241
LEU A 310
MET A 239
PHE A 194
 None
SO4  A 401 ( 4.6A)
None
None
None
 1.33A 4pgfA-5ep0A:
6.6		 4pgfA-5ep0A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4PGF_B_ADNB502_1
(ADENOSYLHOMOCYSTEINA
SE)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		5 / 12 GLU A 177
ASP A 241
LEU A 310
MET A 239
PHE A 194
 None
SO4  A 401 ( 4.6A)
None
None
None
 1.35A 4pgfB-5ep0A:
2.0		 4pgfB-5ep0A:
21.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		5 / 10 ALA A  90
VAL A  91
ASP A  88
PHE A 101
SER A 340
 None
 1.39A 4xp1A-5ep0A:
undetectable		 4xp1A-5ep0A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EB5_A_010A609_0
(HNL ISOENZYME 5)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		5 / 11 ALA A 229
ALA A 233
LEU A 238
LEU A 254
TYR A 263
 None
 1.21A 5eb5A-5ep0A:
undetectable		 5eb5A-5ep0A:
22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F3N_C_ADNC505_1
(-)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		5 / 12 GLU A 177
ASP A 241
LEU A 310
MET A 239
PHE A 194
 None
SO4  A 401 ( 4.6A)
None
None
None
 1.34A 6f3nC-5ep0A:
7.5		 6f3nC-5ep0A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F5U_A_CQNA610_1
(ENVELOPE
GLYCOPROTEIN,ENVELOP
E GLYCOPROTEIN,GP1
ENVELOPE
GLYCOPROTEIN)		 5ep0 PUTATIVE REPRESSOR
PROTEIN LUXO
(Photobacterium
angustum) 		5 / 10 ARG A 112
VAL A 115
LEU A  23
LEU A 102
LEU A  52
 None
 0.94A 6f5uA-5ep0A:
undetectable
6f5uB-5ep0A:
undetectable		 6f5uA-5ep0A:
12.89
6f5uB-5ep0A:
12.05