SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ep5'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GWY_E_010E6_0
(N-[(5-METHYLISOXAZOL
-3-YL)CARBONYL]ALANY
L-L-VALYL-N~1~-((1R,
2Z)-4-(BENZYLOXY)-4-
OXO-1-{[(3R)-2-OXOPY
RROLIDIN-3-YL]METHYL
}BUT-2-ENYL)-L-LEUCI
NAMIDE
MAIN PROTEASE)		 5ep5 THIOESTERASE
(Staphylococcus
aureus) 		4 / 4 THR A  86
LEU A  19
HIS A  14
GLY A  18
 None
 1.41A 5gwyA-5ep5A:
undetectable		 5gwyA-5ep5A:
17.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JWA_A_ACTA609_0
(NADH DEHYDROGENASE,
PUTATIVE)		 5ep5 THIOESTERASE
(Staphylococcus
aureus) 		3 / 3 VAL A 118
SER A  51
TRP A  99
 None
 0.80A 5jwaA-5ep5A:
undetectable		 5jwaA-5ep5A:
13.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VCE_A_RITA602_1
(CYTOCHROME P450 3A4)		 5ep5 THIOESTERASE
(Staphylococcus
aureus) 		5 / 12 ILE A  90
ALA A  72
THR A 112
ILE A 103
ALA A  85
 None
 1.08A 5vceA-5ep5A:
undetectable		 5vceA-5ep5A:
12.71