SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5ep8'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CMA_A_SAMA105_0
(PROTEIN (MET
REPRESSOR))		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 GLU A 297
ARG A 293
LEU A 273
GLU A 270
 GLU  A 297 ( 0.6A)
ARG  A 293 ( 0.6A)
LEU  A 273 ( 0.6A)
GLU  A 270 ( 0.6A)
 1.06A 1cmaA-5ep8A:
undetectable
1cmaB-5ep8A:
undetectable		 1cmaA-5ep8A:
17.07
1cmaB-5ep8A:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_B_URFB2011_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 0.97A 1rxcB-5ep8A:
3.4		 1rxcB-5ep8A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_C_URFC2081_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 7 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 0.95A 1rxcC-5ep8A:
3.4		 1rxcC-5ep8A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_D_URFD2021_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 7 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 0.94A 1rxcD-5ep8A:
3.2		 1rxcD-5ep8A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_E_URFE2031_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 0.96A 1rxcE-5ep8A:
3.4		 1rxcE-5ep8A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_F_URFF2001_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 7 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 1.00A 1rxcF-5ep8A:
3.4		 1rxcF-5ep8A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_K_URFK2061_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 0.97A 1rxcK-5ep8A:
3.1		 1rxcK-5ep8A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RXC_L_URFL2071_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 7 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 0.98A 1rxcL-5ep8A:
3.2		 1rxcL-5ep8A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HDN_L_TACL6888_1
(ELONGATION FACTOR
EF-TU)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 6 SER A 237
VAL A 200
THR A  91
ASP A  89
 SER  A 237 ( 0.0A)
VAL  A 200 ( 0.6A)
THR  A  91 ( 0.8A)
ASP  A  89 ( 0.6A)
 1.28A 2hdnJ-5ep8A:
2.4
2hdnK-5ep8A:
undetectable
2hdnL-5ep8A:
2.6		 2hdnJ-5ep8A:
21.43
2hdnK-5ep8A:
9.45
2hdnL-5ep8A:
21.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WEK_A_DIFA1376_1
(ZINC-BINDING ALCOHOL
DEHYDROGENASE
DOMAIN-CONTAINING
PROTEIN 2)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 LEU A 296
LEU A 102
LYS A 285
ALA A 286
 LEU  A 296 ( 0.5A)
LEU  A 102 ( 0.6A)
LYS  A 285 ( 0.0A)
ALA  A 286 ( 0.0A)
 1.00A 2wekA-5ep8A:
undetectable		 2wekA-5ep8A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FXR_A_ASCA3001_0
(LYSR TYPE REGULATOR
OF TSAMBCD)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 ARG A 168
ALA A  42
ILE A  45
PRO A 178
 ARG  A 168 ( 0.6A)
ALA  A  42 ( 0.0A)
ILE  A  45 ( 0.7A)
PRO  A 178 ( 1.1A)
 1.03A 3fxrA-5ep8A:
undetectable		 3fxrA-5ep8A:
22.90
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NMU_F_SAMF228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		5 / 12 GLY A 203
ALA A 204
ASP A 213
ALA A 214
ASP A 238
 GLY  A 203 ( 0.0A)
ALA  A 204 ( 0.0A)
ASP  A 213 ( 0.6A)
ALA  A 214 ( 0.0A)
ASP  A 238 ( 0.6A)
 1.35A 3nmuA-5ep8A:
undetectable
3nmuF-5ep8A:
undetectable		 3nmuA-5ep8A:
23.25
3nmuF-5ep8A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		5 / 12 GLY A 203
ALA A 204
ASP A 213
ALA A 214
ASP A 238
 GLY  A 203 ( 0.0A)
ALA  A 204 ( 0.0A)
ASP  A 213 ( 0.6A)
ALA  A 214 ( 0.0A)
ASP  A 238 ( 0.6A)
 1.26A 3nvkF-5ep8A:
undetectable
3nvkJ-5ep8A:
undetectable		 3nvkF-5ep8A:
23.03
3nvkJ-5ep8A:
18.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_C_ACTC502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		3 / 3 PRO A 105
ASP A 103
GLU A  75
 PRO  A 105 ( 1.1A)
ASP  A 103 ( 0.6A)
GLU  A  75 ( 0.6A)
 0.83A 3v4tC-5ep8A:
undetectable		 3v4tC-5ep8A:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_H_ACTH503_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 7 ALA A 246
ILE A 247
ARG A 381
GLY A 377
 ALA  A 246 ( 0.0A)
ILE  A 247 ( 0.6A)
ARG  A 381 ( 0.6A)
GLY  A 377 ( 0.0A)
 0.96A 3v4tH-5ep8A:
undetectable		 3v4tH-5ep8A:
26.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_C_PXLC300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 GLY A 262
ASP A 258
GLY A 264
VAL A 272
 GLY  A 262 ( 0.0A)
ASP  A 258 ( 0.6A)
GLY  A 264 ( 0.0A)
VAL  A 272 ( 0.6A)
 0.69A 4c5nC-5ep8A:
undetectable		 4c5nC-5ep8A:
23.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_A_URFA1301_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 0.93A 4e1vA-5ep8A:
3.2		 4e1vA-5ep8A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_B_URFB1301_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 7 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 0.92A 4e1vB-5ep8A:
3.0		 4e1vB-5ep8A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_C_URFC1301_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 0.92A 4e1vC-5ep8A:
3.1		 4e1vC-5ep8A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_D_URFD1301_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 0.93A 4e1vD-5ep8A:
3.1		 4e1vD-5ep8A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_E_URFE1301_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 0.96A 4e1vE-5ep8A:
3.2		 4e1vE-5ep8A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_G_URFG1301_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 0.94A 4e1vG-5ep8A:
3.0		 4e1vG-5ep8A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4E1V_H_URFH1301_1
(URIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 GLY A 355
ILE A 247
VAL A  87
PRO A 242
 GLY  A 355 ( 0.0A)
ILE  A 247 ( 0.6A)
VAL  A  87 ( 0.6A)
PRO  A 242 ( 1.1A)
 0.90A 4e1vH-5ep8A:
3.3		 4e1vH-5ep8A:
20.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		5 / 12 LEU A 329
ILE A 127
ILE A 257
ALA A 256
GLY A 119
 LEU  A 329 ( 0.6A)
ILE  A 127 ( 0.6A)
ILE  A 257 ( 0.6A)
ALA  A 256 ( 0.0A)
GLY  A 119 ( 0.0A)
 1.04A 4enhA-5ep8A:
undetectable		 4enhA-5ep8A:
21.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ENH_A_FVXA602_1
(CHOLESTEROL
24-HYDROXYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		5 / 12 PHE A 309
LEU A 329
ILE A 127
ALA A 256
GLY A 119
 PHE  A 309 ( 1.3A)
LEU  A 329 ( 0.6A)
ILE  A 127 ( 0.6A)
ALA  A 256 ( 0.0A)
GLY  A 119 ( 0.0A)
 1.03A 4enhA-5ep8A:
undetectable		 4enhA-5ep8A:
21.68
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4LHM_A_AZZA510_1
(THYMIDINE
PHOSPHORYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		8 / 11 THR A  84
TYR A 165
ARG A 168
VAL A 174
ILE A 180
SER A 183
MET A 208
LEU A 217
 THR  A  84 ( 0.8A)
TYR  A 165 ( 1.3A)
ARG  A 168 ( 0.6A)
VAL  A 174 ( 0.5A)
ILE  A 180 ( 0.7A)
SER  A 183 ( 0.0A)
MET  A 208 ( 0.0A)
LEU  A 217 ( 0.6A)
 0.63A 4lhmA-5ep8A:
52.9		 4lhmA-5ep8A:
45.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MWZ_B_CQAB303_0
(PHOSPHOETHANOLAMINE
N-METHYLTRANSFERASE,
PUTATIVE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 GLY A  88
LEU A 251
GLU A 252
LYS A 254
 GLY  A  88 ( 0.0A)
LEU  A 251 ( 0.6A)
GLU  A 252 ( 0.6A)
LYS  A 254 ( 0.0A)
 0.62A 4mwzB-5ep8A:
undetectable		 4mwzB-5ep8A:
22.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_A_SAMA301_0
(PUTATIVE RNA
METHYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		5 / 12 GLY A 225
ASN A 226
ASP A  52
ILE A 184
SER A 183
 GLY  A 225 ( 0.0A)
ASN  A 226 ( 0.6A)
ASP  A  52 ( 0.6A)
ILE  A 184 ( 0.4A)
SER  A 183 ( 0.0A)
 1.28A 4pooA-5ep8A:
undetectable		 4pooA-5ep8A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4POO_B_SAMB301_0
(PUTATIVE RNA
METHYLASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		5 / 12 GLY A 225
ASN A 226
ASP A  52
ILE A 184
SER A 183
 GLY  A 225 ( 0.0A)
ASN  A 226 ( 0.6A)
ASP  A  52 ( 0.6A)
ILE  A 184 ( 0.4A)
SER  A 183 ( 0.0A)
 1.32A 4pooB-5ep8A:
undetectable		 4pooB-5ep8A:
19.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_B_SAMB2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		5 / 12 GLY A  88
GLY A  86
LEU A 251
THR A 396
LYS A 383
 GLY  A  88 ( 0.0A)
GLY  A  86 ( 0.0A)
LEU  A 251 ( 0.6A)
THR  A 396 ( 0.8A)
LYS  A 383 ( 0.0A)
 1.09A 4uckB-5ep8A:
undetectable		 4uckB-5ep8A:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4W5Q_A_IPHA905_0
(PROTEIN ARGONAUTE-2)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 6 ASP A 213
ALA A 215
THR A 210
THR A 202
 ASP  A 213 ( 0.6A)
ALA  A 215 ( 0.0A)
THR  A 210 ( 0.8A)
THR  A 202 ( 0.8A)
 1.44A 4w5qA-5ep8A:
undetectable		 4w5qA-5ep8A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z4F_A_IPHA904_0
(PROTEIN ARGONAUTE-2)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 6 ASP A 213
ALA A 215
THR A 210
THR A 202
 ASP  A 213 ( 0.6A)
ALA  A 215 ( 0.0A)
THR  A 210 ( 0.8A)
THR  A 202 ( 0.8A)
 1.44A 4z4fA-5ep8A:
undetectable		 4z4fA-5ep8A:
19.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		5 / 12 SER A 347
GLU A 348
GLU A 211
THR A 202
GLY A 203
 SER  A 347 ( 0.0A)
GLU  A 348 ( 0.6A)
GLU  A 211 ( 0.6A)
THR  A 202 ( 0.8A)
GLY  A 203 ( 0.0A)
 1.45A 4zjlA-5ep8A:
undetectable		 4zjlA-5ep8A:
18.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZN7_A_DESA601_1
(ESTROGEN RECEPTOR)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		5 / 12 LEU A 289
ALA A 292
GLU A 291
MET A 233
LEU A 296
 LEU  A 289 ( 0.6A)
ALA  A 292 ( 0.0A)
GLU  A 291 ( 0.6A)
MET  A 233 ( 0.0A)
LEU  A 296 ( 0.5A)
 1.02A 4zn7A-5ep8A:
undetectable		 4zn7A-5ep8A:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		5 / 12 GLY A 364
GLY A 115
GLY A 113
ALA A 358
HIS A 116
 GLY  A 364 ( 0.0A)
GLY  A 115 ( 0.0A)
GLY  A 113 ( 0.0A)
ALA  A 358 ( 0.0A)
HIS  A 116 ( 1.0A)
 1.07A 5c0oE-5ep8A:
undetectable		 5c0oE-5ep8A:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5CXV_A_0HKA501_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M1,ENDOLYSIN,MUSCARI
NIC ACETYLCHOLINE
RECEPTOR M1)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		3 / 3 THR A 210
THR A 202
PHE A 207
 THR  A 210 ( 0.8A)
THR  A 202 ( 0.8A)
PHE  A 207 ( 1.3A)
 0.83A 5cxvA-5ep8A:
undetectable		 5cxvA-5ep8A:
21.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5E26_D_PAUD601_0
(PANTOTHENATE KINASE
2, MITOCHONDRIAL)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 8 VAL A 407
ALA A 357
GLY A 355
GLY A 364
 VAL  A 407 ( 0.6A)
ALA  A 357 ( 0.0A)
GLY  A 355 ( 0.0A)
GLY  A 364 ( 0.0A)
 0.85A 5e26C-5ep8A:
undetectable
5e26D-5ep8A:
undetectable		 5e26C-5ep8A:
23.17
5e26D-5ep8A:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGT_A_ERYA402_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		5 / 12 PRO A 242
VAL A 411
ALA A 340
VAL A 395
GLY A 344
 PRO  A 242 ( 1.1A)
VAL  A 411 ( 0.6A)
ALA  A 340 ( 0.0A)
VAL  A 395 ( 0.5A)
GLY  A 344 ( 0.0A)
 1.03A 5igtA-5ep8A:
undetectable		 5igtA-5ep8A:
23.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M78_A_SALA304_1
(CARBONIC ANHYDRASE 2)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 7 VAL A 197
LEU A  95
THR A  92
THR A  91
 VAL  A 197 ( 0.6A)
LEU  A  95 ( 0.6A)
THR  A  92 (-0.8A)
THR  A  91 ( 0.8A)
 0.75A 5m78A-5ep8A:
undetectable		 5m78A-5ep8A:
14.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VIM_B_SAMB301_0
(METHYLTRANSFERASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		6 / 12 GLY A 115
GLY A 248
GLY A 364
GLU A 252
VAL A 395
ILE A 354
 GLY  A 115 ( 0.0A)
GLY  A 248 ( 0.0A)
GLY  A 364 ( 0.0A)
GLU  A 252 ( 0.6A)
VAL  A 395 ( 0.5A)
ILE  A 354 ( 0.7A)
 1.31A 5vimB-5ep8A:
undetectable		 5vimB-5ep8A:
21.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WZ2_C_SAMC601_0
(NS5 MTASE)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		6 / 12 GLY A 115
GLY A 248
GLY A 364
GLU A 252
VAL A 395
ILE A 354
 GLY  A 115 ( 0.0A)
GLY  A 248 ( 0.0A)
GLY  A 364 ( 0.0A)
GLU  A 252 ( 0.6A)
VAL  A 395 ( 0.5A)
ILE  A 354 ( 0.7A)
 1.31A 5wz2C-5ep8A:
undetectable		 5wz2C-5ep8A:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BQG_A_ERMA1201_1
(5-HYDROXYTRYPTAMINE
RECEPTOR 2C,SOLUBLE
CYTOCHROME B562)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		5 / 12 SER A 110
GLY A 192
ALA A 191
PHE A 139
ASN A 315
 SER  A 110 (-0.0A)
GLY  A 192 ( 0.0A)
ALA  A 191 ( 0.0A)
PHE  A 139 ( 1.3A)
ASN  A 315 ( 0.6A)
 1.19A 6bqgA-5ep8A:
undetectable		 6bqgA-5ep8A:
9.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EU9_D_READ601_1
(RETINOIC ACID
RECEPTOR)		 5ep8 PYRIMIDINE-NUCLEOSID
E PHOSPHORYLASE
(Bacillus
subtilis) 		4 / 7 LEU A 306
GLY A 262
LEU A 296
GLY A 276
 LEU  A 306 ( 0.6A)
GLY  A 262 ( 0.0A)
LEU  A 296 ( 0.5A)
GLY  A 276 ( 0.0A)
 0.70A 6eu9D-5ep8A:
undetectable		 6eu9D-5ep8A:
13.15