SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5epf'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1E7C_A_HLTA4007_1
(SERUM ALBUMIN)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		4 / 8 HIS A  58
PHE A  59
ASP A 150
LEU A 153
 None
 0.81A 1e7cA-5epfA:
undetectable		 1e7cA-5epfA:
15.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_A_BEZA1162_0
(PEROXIREDOXIN 5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		6 / 10 PRO A  45
THR A  49
PRO A  50
GLY A  51
CYH A  52
ARG A 124
 None
 0.90A 1h4oA-5epfA:
20.9
1h4oB-5epfA:
21.1		 1h4oA-5epfA:
28.65
1h4oB-5epfA:
28.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_B_BEZB1162_0
(PEROXIREDOXIN 5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		6 / 8 PRO A  45
THR A  49
PRO A  50
GLY A  51
CYH A  52
ARG A 124
 None
 0.92A 1h4oB-5epfA:
21.1		 1h4oB-5epfA:
28.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_C_BEZC1162_0
(PEROXIREDOXIN 5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		6 / 9 PRO A  45
THR A  49
PRO A  50
GLY A  51
CYH A  52
ARG A 124
 None
 0.92A 1h4oC-5epfA:
21.0
1h4oD-5epfA:
21.0		 1h4oC-5epfA:
28.65
1h4oD-5epfA:
28.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_D_BEZD1162_0
(PEROXIREDOXIN 5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		6 / 9 PRO A  45
THR A  49
PRO A  50
GLY A  51
CYH A  52
ARG A 124
 None
 0.92A 1h4oD-5epfA:
21.0		 1h4oD-5epfA:
28.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_E_BEZE1162_0
(PEROXIREDOXIN 5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		6 / 9 PRO A  45
THR A  49
PRO A  50
GLY A  51
CYH A  52
ARG A 124
 None
 0.93A 1h4oE-5epfA:
21.0
1h4oF-5epfA:
21.0		 1h4oE-5epfA:
28.65
1h4oF-5epfA:
28.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_F_BEZF1162_0
(PEROXIREDOXIN 5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		6 / 9 PRO A  45
THR A  49
PRO A  50
GLY A  51
CYH A  52
ARG A 124
 None
 0.91A 1h4oF-5epfA:
21.0		 1h4oF-5epfA:
28.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_G_BEZG1162_0
(PEROXIREDOXIN 5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		6 / 8 PRO A  45
THR A  49
PRO A  50
GLY A  51
CYH A  52
ARG A 124
 None
 0.90A 1h4oG-5epfA:
20.8		 1h4oG-5epfA:
28.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1H4O_H_BEZH1162_0
(PEROXIREDOXIN 5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		6 / 9 PRO A  45
THR A  49
PRO A  50
GLY A  51
CYH A  52
ARG A 124
 None
 0.89A 1h4oH-5epfA:
20.9		 1h4oH-5epfA:
28.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HD2_A_BEZA201_0
(PEROXIREDOXIN 5
RESIDUES 54-214)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		6 / 9 PRO A  45
THR A  49
PRO A  50
GLY A  51
CYH A  52
ARG A 124
 None
 0.92A 1hd2A-5epfA:
21.0		 1hd2A-5epfA:
28.65
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OC3_A_BEZA201_0
(PEROXIREDOXIN 5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		6 / 8 PRO A  45
THR A  49
PRO A  50
GLY A  51
CYH A  52
ARG A 124
 None
 0.94A 1oc3A-5epfA:
20.9		 1oc3A-5epfA:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OC3_B_BEZB201_0
(PEROXIREDOXIN 5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		6 / 9 PRO A  45
THR A  49
PRO A  50
GLY A  51
CYH A  52
ARG A 124
 None
 0.92A 1oc3B-5epfA:
20.7		 1oc3B-5epfA:
30.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1URM_A_BEZA201_0
(PEROXIREDOXIN 5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		5 / 9 PRO A  45
THR A  49
PRO A  50
GLY A  51
ARG A 124
 None
 0.68A 1urmA-5epfA:
20.7		 1urmA-5epfA:
29.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_A_TFPA204_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		4 / 7 PHE A  18
LEU A  33
PHE A 109
VAL A 138
 None
 1.12A 1wrlA-5epfA:
undetectable
1wrlB-5epfA:
undetectable		 1wrlA-5epfA:
18.52
1wrlB-5epfA:
18.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V32_C_BEZC1222_0
(PEROXIREDOXIN 6)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		4 / 8 PRO A  45
THR A  49
PRO A  50
ARG A 124
 None
 0.64A 2v32C-5epfA:
18.9
2v32D-5epfA:
20.9		 2v32C-5epfA:
21.34
2v32D-5epfA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_C_BEZC1218_0
(PEROXIREDOXIN 6.)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		4 / 8 PRO A  45
THR A  49
PRO A  50
ARG A 124
 None
 0.70A 2v41C-5epfA:
20.6
2v41D-5epfA:
21.0		 2v41C-5epfA:
21.34
2v41D-5epfA:
21.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V41_H_BEZH1222_0
(PEROXIREDOXIN 6.)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		4 / 8 PRO A  45
THR A  49
PRO A  50
ARG A 124
 None
 0.68A 2v41G-5epfA:
19.0
2v41H-5epfA:
18.9		 2v41G-5epfA:
21.34
2v41H-5epfA:
21.34
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		5 / 10 PRO A  45
PRO A  50
GLY A  51
CYH A  52
ARG A 124
 None
 0.95A 2vl2A-5epfA:
20.9
2vl2C-5epfA:
18.4		 2vl2A-5epfA:
30.37
2vl2C-5epfA:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VL2_A_BEZA1162_0
(PEROXIREDOXIN-5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		5 / 10 PRO A  45
THR A  49
PRO A  50
GLY A  51
ARG A 124
 None
 0.54A 2vl2A-5epfA:
20.9
2vl2C-5epfA:
18.4		 2vl2A-5epfA:
30.37
2vl2C-5epfA:
30.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2VL2_B_BEZB1162_0
(PEROXIREDOXIN-5)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		4 / 7 PRO A  45
THR A  49
PRO A  50
GLY A  51
 None
 0.56A 2vl2B-5epfA:
20.7		 2vl2B-5epfA:
30.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HS6_A_EPAA1_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		5 / 12 VAL A  40
TYR A  95
ALA A 149
LEU A 153
LEU A 156
 None
 0.99A 3hs6A-5epfA:
undetectable		 3hs6A-5epfA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LB0_B_ACTB401_0
(UNCHARACTERIZED
PROTEIN)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		4 / 5 VAL A  40
LEU A 156
VAL A  69
PHE A  66
 None
 0.96A 4lb0B-5epfA:
undetectable		 4lb0B-5epfA:
18.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LV9_B_20JB602_1
(NICOTINAMIDE
PHOSPHORIBOSYLTRANSF
ERASE)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		4 / 7 VAL A 128
ARG A 157
ILE A 159
ALA A 158
 None
 0.76A 4lv9B-5epfA:
undetectable		 4lv9B-5epfA:
14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D4N_C_ACTC201_0
(NITROGEN REGULATORY
PROTEIN P-II)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		4 / 5 VAL A 105
VAL A 111
GLY A 110
PHE A  43
 None
 0.98A 5d4nA-5epfA:
undetectable
5d4nC-5epfA:
undetectable		 5d4nA-5epfA:
22.35
5d4nC-5epfA:
22.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_B_DAHB123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		5 / 10 PHE A  43
THR A 126
GLY A  75
ILE A  76
ILE A 129
 None
 1.25A 6ebpB-5epfA:
undetectable		 6ebpB-5epfA:
21.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EBP_C_DAHC123_0
(RIBONUCLEOSIDE-DIPHO
SPHATE REDUCTASE,
BETA SUBUNIT)		 5epf PEROXIREDOXIN
(Mycobacterium
tuberculosis) 		5 / 10 PHE A  43
THR A 126
GLY A  75
ILE A  76
ILE A 129
 None
 1.24A 6ebpC-5epfA:
undetectable		 6ebpC-5epfA:
21.21