SIMILAR PATTERN OF AMINO ACIDS MAPPED TO '5epg'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 10 GLY A 120
THR A  53
THR A 127
SER A 347
ALA A 143
 None
 1.41A 1gtnO-5epgA:
undetectable
1gtnP-5epgA:
undetectable		 1gtnO-5epgA:
4.77
1gtnP-5epgA:
4.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_Q_TRPQ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 9 GLY A 120
THR A  53
THR A 127
SER A 347
ALA A 143
 None
 1.47A 1gtnQ-5epgA:
undetectable
1gtnR-5epgA:
undetectable		 1gtnQ-5epgA:
4.77
1gtnR-5epgA:
4.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 GLY A1048
GLY A1050
GLU A1046
ARG A 802
GLY A 804
 MTE  A3003 (-3.5A)
None
None
None
None
 0.95A 1jg3A-5epgA:
undetectable		 1jg3A-5epgA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG3_B_ADNB550_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 GLY A1048
GLY A1050
GLU A1046
ARG A 802
GLY A 804
 MTE  A3003 (-3.5A)
None
None
None
None
 0.92A 1jg3B-5epgA:
undetectable		 1jg3B-5epgA:
10.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K6C_B_MK1B902_2
(POL POLYPROTEIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 GLY A 809
ALA A 806
GLY A1087
ILE A1085
VAL A 803
 None
MTE  A3003 (-3.8A)
MTE  A3003 ( 3.4A)
None
None
 0.87A 1k6cB-5epgA:
undetectable		 1k6cB-5epgA:
6.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQT_A_ACTA1869_0
(FPRA)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 4 ASP A1186
HIS A1249
ARG A1184
GLU A1247
 None
 1.01A 1lqtA-5epgA:
undetectable		 1lqtA-5epgA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LQU_A_ACTA1426_0
(FPRA)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 4 ASP A1186
HIS A1249
ARG A1184
GLU A1247
 None
 0.87A 1lquA-5epgA:
undetectable		 1lquA-5epgA:
16.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Q8J_B_C2FB802_0
(5-METHYLTETRAHYDROFO
LATE S-HOMOCYSTEINE
METHYLTRANSFERASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 GLY A1232
ASN A  72
GLY A 346
ASN A 436
ILE A 349
 None
FES  A3002 ( 3.8A)
None
None
FAD  A3004 ( 4.3A)
 1.08A 1q8jB-5epgA:
undetectable		 1q8jB-5epgA:
18.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RG7_A_MTXA161_1
(DIHYDROFOLATE
REDUCTASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 ASN A 369
LEU A 392
SER A 361
ILE A 360
LEU A 405
 None
None
FAD  A3004 ( 3.7A)
FAD  A3004 ( 4.0A)
None
 1.02A 1rg7A-5epgA:
undetectable		 1rg7A-5epgA:
8.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RU9_H_ACTH611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 6 LEU A 528
TRP A1002
LEU A1176
PHE A1319
 None
 0.80A 1ru9H-5epgA:
undetectable
1ru9L-5epgA:
undetectable		 1ru9H-5epgA:
10.33
1ru9L-5epgA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RUK_L_ACTL611_0
(IMMUNOGLOBULIN
IGG2A, HEAVY CHAIN
IMMUNOGLOBULIN
IGG2A, LIGHT CHAIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 6 LEU A 528
TRP A1002
LEU A1176
PHE A1319
 None
 0.75A 1rukH-5epgA:
undetectable
1rukL-5epgA:
undetectable		 1rukH-5epgA:
10.33
1rukL-5epgA:
10.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1SG9_C_SAMC303_0
(HEMK PROTEIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 PRO A 219
GLY A  83
ALA A  85
PRO A  61
ALA A 226
 None
 0.98A 1sg9C-5epgA:
2.0		 1sg9C-5epgA:
13.68
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6002_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 7 GLN A 673
ALA A 878
ARG A 619
ASN A 913
 None
 1.38A 1t9wA-5epgA:
undetectable		 1t9wA-5epgA:
22.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_O_CHDO3085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 ARG A 921
PHE A 807
GLY A 808
GLY A1088
GLN A1049
 MTE  A3003 (-3.7A)
MTE  A3003 (-3.7A)
MOS  A3005 (-4.0A)
MOS  A3005 ( 3.4A)
MTE  A3003 (-4.4A)
 0.97A 1v54G-5epgA:
undetectable
1v54N-5epgA:
undetectable
1v54O-5epgA:
undetectable		 1v54G-5epgA:
5.22
1v54N-5epgA:
16.15
1v54O-5epgA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_O_CHDO3085_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE II
CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 ARG A 921
PHE A 807
GLY A 808
GLY A1088
GLN A1049
 MTE  A3003 (-3.7A)
MTE  A3003 (-3.7A)
MOS  A3005 (-4.0A)
MOS  A3005 ( 3.4A)
MTE  A3003 (-4.4A)
 1.00A 1v55G-5epgA:
undetectable
1v55N-5epgA:
0.0
1v55O-5epgA:
undetectable		 1v55G-5epgA:
5.22
1v55N-5epgA:
16.15
1v55O-5epgA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XOQ_B_ROFB501_1
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		3 / 3 MET A 753
ASN A 436
GLN A1235
 FES  A3001 (-4.9A)
None
None
 1.03A 1xoqB-5epgA:
undetectable		 1xoqB-5epgA:
13.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZLQ_A_ACTA1502_0
(NICKEL-BINDING
PERIPLASMIC PROTEIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 PRO A  70
GLY A  50
ASN A 147
GLY A 146
 None
FES  A3002 (-3.4A)
None
None
 1.11A 1zlqA-5epgA:
undetectable		 1zlqA-5epgA:
17.57
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_0
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 ILE A 784
GLY A 815
VAL A 803
PRO A 778
ILE A1045
 None
 1.11A 1zq9A-5epgA:
undetectable		 1zq9A-5epgA:
12.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 ARG A 921
PHE A 807
GLY A 808
GLY A1088
GLN A1049
 MTE  A3003 (-3.7A)
MTE  A3003 (-3.7A)
MOS  A3005 (-4.0A)
MOS  A3005 ( 3.4A)
MTE  A3003 (-4.4A)
 1.00A 2dyrG-5epgA:
undetectable
2dyrN-5epgA:
undetectable
2dyrO-5epgA:
undetectable		 2dyrG-5epgA:
5.22
2dyrN-5epgA:
16.15
2dyrO-5epgA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_A_C2FA3000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 ASN A  72
GLY A 346
ASN A 436
ARG A 429
ILE A 349
 FES  A3002 ( 3.8A)
None
None
FAD  A3004 (-4.1A)
FAD  A3004 ( 4.3A)
 1.20A 2e7fA-5epgA:
undetectable		 2e7fA-5epgA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2E7F_B_C2FB4000_0
(5-METHYLTETRAHYDROFO
LATE CORRINOID/IRON
SULFUR PROTEIN
METHYLTRANSFERASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 ASN A  72
GLY A 346
ASN A 436
ARG A 429
ILE A 349
 FES  A3002 ( 3.8A)
None
None
FAD  A3004 (-4.1A)
FAD  A3004 ( 4.3A)
 1.22A 2e7fB-5epgA:
undetectable		 2e7fB-5epgA:
12.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 ARG A 921
PHE A 807
GLY A 808
GLY A1088
GLN A1049
 MTE  A3003 (-3.7A)
MTE  A3003 (-3.7A)
MOS  A3005 (-4.0A)
MOS  A3005 ( 3.4A)
MTE  A3003 (-4.4A)
 1.01A 2eijG-5epgA:
undetectable
2eijN-5epgA:
0.0
2eijO-5epgA:
undetectable		 2eijG-5epgA:
5.22
2eijN-5epgA:
16.15
2eijO-5epgA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 ARG A 921
PHE A 807
GLY A 808
GLY A1088
GLN A1049
 MTE  A3003 (-3.7A)
MTE  A3003 (-3.7A)
MOS  A3005 (-4.0A)
MOS  A3005 ( 3.4A)
MTE  A3003 (-4.4A)
 1.01A 2eikG-5epgA:
undetectable
2eikN-5epgA:
0.0
2eikO-5epgA:
undetectable		 2eikG-5epgA:
5.22
2eikN-5epgA:
16.15
2eikO-5epgA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_O_CHDO229_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE
VIA-HEART
CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 ARG A 921
PHE A 807
GLY A 808
GLY A1088
GLN A1049
 MTE  A3003 (-3.7A)
MTE  A3003 (-3.7A)
MOS  A3005 (-4.0A)
MOS  A3005 ( 3.4A)
MTE  A3003 (-4.4A)
 0.99A 2eilG-5epgA:
undetectable
2eilN-5epgA:
undetectable
2eilO-5epgA:
undetectable		 2eilG-5epgA:
5.22
2eilN-5epgA:
16.15
2eilO-5epgA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKK_A_2FAA501_2
(ADENOSINE KINASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 4 ALA A1282
VAL A1010
PHE A1280
THR A 937
 None
 1.25A 2pkkA-5epgA:
undetectable		 2pkkA-5epgA:
13.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VJ1_A_BEZA1303_0
(SARS CORONAVIRUS
MAIN PROTEINASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		3 / 3 HIS A 872
MET A 870
MET A 894
 None
 1.32A 2vj1A-5epgA:
undetectable		 2vj1A-5epgA:
12.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y6R_B_CTCB1385_0
(TETX2 PROTEIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 8 GLN A 927
PHE A 923
GLY A 924
GLY A 809
 None
MOS  A3005 (-4.2A)
None
None
 0.70A 2y6rB-5epgA:
undetectable		 2y6rB-5epgA:
14.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 GLY A1088
GLN A1049
ARG A 921
PHE A 807
GLY A 808
 MOS  A3005 ( 3.4A)
MTE  A3003 (-4.4A)
MTE  A3003 (-3.7A)
MTE  A3003 (-3.7A)
MOS  A3005 (-4.0A)
 1.06A 3ag3A-5epgA:
0.2
3ag3B-5epgA:
undetectable
3ag3T-5epgA:
undetectable		 3ag3A-5epgA:
16.15
3ag3B-5epgA:
11.18
3ag3T-5epgA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_O_CHDO229_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 ARG A 921
PHE A 807
GLY A 808
GLY A1088
GLN A1049
 MTE  A3003 (-3.7A)
MTE  A3003 (-3.7A)
MOS  A3005 (-4.0A)
MOS  A3005 ( 3.4A)
MTE  A3003 (-4.4A)
 0.97A 3ag3G-5epgA:
undetectable
3ag3N-5epgA:
undetectable
3ag3O-5epgA:
undetectable		 3ag3G-5epgA:
5.22
3ag3N-5epgA:
16.15
3ag3O-5epgA:
11.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AQI_B_CHDB4_0
(FERROCHELATASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 6 ARG A  32
PRO A  70
GLY A 120
MET A 123
 None
 1.49A 3aqiB-5epgA:
undetectable		 3aqiB-5epgA:
14.09
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ARU_A_PNXA606_1
(CHITINASE A)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 7 PHE A 116
GLY A  43
ASP A 601
ARG A 833
 None
FES  A3002 (-3.9A)
None
None
 1.26A 3aruA-5epgA:
undetectable		 3aruA-5epgA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_B_CHDB1085_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 GLY A1088
GLN A1049
ARG A 921
PHE A 807
GLY A 808
 MOS  A3005 ( 3.4A)
MTE  A3003 (-4.4A)
MTE  A3003 (-3.7A)
MTE  A3003 (-3.7A)
MOS  A3005 (-4.0A)
 1.00A 3asoA-5epgA:
0.0
3asoB-5epgA:
undetectable
3asoT-5epgA:
undetectable		 3asoA-5epgA:
16.15
3asoB-5epgA:
11.18
3asoT-5epgA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AXT_A_SAMA397_0
(PROBABLE
N(2),N(2)-DIMETHYLGU
ANOSINE TRNA
METHYLTRANSFERASE
TRM1)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 ALA A 160
ILE A 158
ARG A 155
GLU A 206
ALA A 203
 None
 1.19A 3axtA-5epgA:
undetectable		 3axtA-5epgA:
14.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CKZ_A_ZMRA469_2
(NEURAMINIDASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 6 ASP A 289
ARG A 234
ILE A 291
SER A 295
 None
 1.10A 3ckzA-5epgA:
undetectable		 3ckzA-5epgA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX94_0
(PROTEIN S100-B)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		3 / 3 PHE A1274
CYH A1277
PHE A1281
 None
 0.96A 3cr5X-5epgA:
undetectable		 3cr5X-5epgA:
5.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CR5_X_PNTX95_0
(PROTEIN S100-B)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		3 / 3 CYH A1277
PHE A1280
PHE A1281
 None
 0.82A 3cr5X-5epgA:
undetectable		 3cr5X-5epgA:
5.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3F8W_B_ADNB301_1
(PURINE-NUCLEOSIDE
PHOSPHORYLASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 HIS A1229
GLY A 505
VAL A 512
GLY A 510
VAL A1332
 None
 1.27A 3f8wB-5epgA:
undetectable		 3f8wB-5epgA:
12.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JUS_B_ECNB602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 9 TYR A 964
PHE A1159
GLY A 890
ALA A 928
THR A 932
 None
 1.35A 3jusB-5epgA:
undetectable		 3jusB-5epgA:
16.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K13_B_THHB643_0
(5-METHYLTETRAHYDROFO
LATE-HOMOCYSTEINE
METHYLTRANSFERASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 ASN A  72
GLY A 346
ASN A 436
ARG A 429
ILE A 349
 FES  A3002 ( 3.8A)
None
None
FAD  A3004 (-4.1A)
FAD  A3004 ( 4.3A)
 1.18A 3k13B-5epgA:
undetectable		 3k13B-5epgA:
13.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_D_TFPD201_1
(PROTEIN S100-A4)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 8 GLY A 595
CYH A  49
CYH A 149
PHE A 807
 None
FES  A3002 (-2.2A)
FES  A3001 (-2.1A)
MTE  A3003 (-3.7A)
 1.04A 3ko0D-5epgA:
undetectable
3ko0E-5epgA:
undetectable		 3ko0D-5epgA:
5.58
3ko0E-5epgA:
5.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LP9_D_SPMD230_1
(LS-24)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		3 / 3 GLU A 554
GLU A 999
ASN A1000
 None
 0.91A 3lp9B-5epgA:
undetectable
3lp9D-5epgA:
undetectable		 3lp9B-5epgA:
10.93
3lp9D-5epgA:
10.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_A_PZIA801_0
(GLUTAMATE RECEPTOR 2)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 8 GLY A 346
PRO A  70
SER A 124
ASN A  72
 None
None
None
FES  A3002 ( 3.8A)
 0.78A 3lslA-5epgA:
undetectable
3lslD-5epgA:
undetectable		 3lslA-5epgA:
12.24
3lslD-5epgA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LSL_G_PZIG801_0
(GLUTAMATE RECEPTOR 2)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		3 / 3 PRO A  70
SER A 124
ASN A  72
 None
None
FES  A3002 ( 3.8A)
 0.69A 3lslG-5epgA:
undetectable		 3lslG-5epgA:
12.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNO_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 GLY A  50
GLN A 348
MET A 121
CYH A 149
ILE A1238
 FES  A3002 (-3.4A)
None
None
FES  A3001 (-2.1A)
None
 1.39A 3mnoA-5epgA:
undetectable		 3mnoA-5epgA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MNP_A_DEXA784_1
(GLUCOCORTICOID
RECEPTOR)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 GLY A  50
GLN A 348
MET A 121
CYH A 149
ILE A1238
 FES  A3002 (-3.4A)
None
None
FES  A3001 (-2.1A)
None
 1.39A 3mnpA-5epgA:
undetectable		 3mnpA-5epgA:
12.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PP7_B_SVRB499_1
(PYRUVATE KINASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 10 THR A 932
PRO A 926
GLY A1276
TYR A1215
ALA A 929
 None
 1.31A 3pp7B-5epgA:
undetectable		 3pp7B-5epgA:
17.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3QOW_A_SAMA417_1
(HISTONE-LYSINE
N-METHYLTRANSFERASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		3 / 3 THR A1177
ASP A 555
GLU A 529
 None
 0.79A 3qowA-5epgA:
undetectable		 3qowA-5epgA:
16.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U7S_A_017A201_1
(POL POLYPROTEIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 9 GLY A 809
ALA A 806
GLY A1087
ILE A1085
VAL A 803
 None
MTE  A3003 (-3.8A)
MTE  A3003 ( 3.4A)
None
None
 0.97A 3u7sA-5epgA:
undetectable		 3u7sA-5epgA:
5.98
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3U88_A_CHDA611_0
(MENIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		3 / 3 SER A 383
PHE A 257
LYS A 256
 None
 0.80A 3u88A-5epgA:
undetectable		 3u88A-5epgA:
17.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_B_MIYB2001_1
(TETX2 PROTEIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 8 GLN A 927
PHE A 923
GLY A 924
GLY A 809
 None
MOS  A3005 (-4.2A)
None
None
 0.62A 3v3nB-5epgA:
undetectable		 3v3nB-5epgA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_C_MIYC2001_1
(TETX2 PROTEIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 8 GLN A 927
PHE A 923
GLY A 924
GLY A 809
 None
MOS  A3005 (-4.2A)
None
None
 0.61A 3v3nC-5epgA:
undetectable		 3v3nC-5epgA:
13.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_E_ACTE502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		3 / 3 LYS A1237
ARG A 429
LEU A 438
 None
FAD  A3004 (-4.1A)
FAD  A3004 (-4.8A)
 1.39A 3v4tE-5epgA:
undetectable		 3v4tE-5epgA:
16.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_A_ACTA1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 6 GLY A1267
VAL A1090
ASP A1093
THR A1261
 None
MTE  A3003 (-4.3A)
None
None
 1.16A 3vqrA-5epgA:
undetectable		 3vqrA-5epgA:
15.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VQR_B_ACTB1002_0
(PUTATIVE
OXIDOREDUCTASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 GLY A1267
VAL A1090
ASP A1093
THR A1261
 None
MTE  A3003 (-4.3A)
None
None
 1.16A 3vqrB-5epgA:
undetectable		 3vqrB-5epgA:
15.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_A_W9TA1004_1
(HEMOLYTIC LECTIN
CEL-III)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 GLU A1170
GLY A1006
TYR A 986
GLU A 948
 None
 1.35A 3w9tA-5epgA:
undetectable		 3w9tA-5epgA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_C_W9TC1002_1
(HEMOLYTIC LECTIN
CEL-III)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 GLU A1170
GLY A1006
TYR A 986
GLU A 948
 None
 1.35A 3w9tC-5epgA:
undetectable		 3w9tC-5epgA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_D_W9TD512_1
(HEMOLYTIC LECTIN
CEL-III)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 GLU A1170
GLY A1006
TYR A 986
GLU A 948
 None
 1.35A 3w9tD-5epgA:
undetectable		 3w9tD-5epgA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3W9T_G_W9TG502_1
(HEMOLYTIC LECTIN
CEL-III)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 GLU A1170
GLY A1006
TYR A 986
GLU A 948
 None
 1.35A 3w9tG-5epgA:
undetectable		 3w9tG-5epgA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4B53_B_ACTB1445_0
(IG GAMMA-4 CHAIN C
REGION)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		3 / 3 GLU A 938
GLY A 741
SER A 934
 None
 0.70A 4b53B-5epgA:
undetectable		 4b53B-5epgA:
5.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BWL_C_MN9C1297_0
(N-ACETYLNEURAMINATE
LYASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 10 ILE A 291
LEU A 249
GLY A 309
GLY A 307
SER A 413
 None
 1.20A 4bwlC-5epgA:
undetectable		 4bwlC-5epgA:
13.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L4B_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 8 TYR A 418
LEU A 326
VAL A 322
VAL A 297
 None
 1.05A 4l4bA-5epgA:
undetectable		 4l4bA-5epgA:
15.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_A_8PRA603_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.04A 4mm4A-5epgA:
undetectable		 4mm4A-5epgA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM4_B_8PRB603_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.01A 4mm4B-5epgA:
undetectable		 4mm4B-5epgA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM5_A_SREA603_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 9 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.14A 4mm5A-5epgA:
undetectable		 4mm5A-5epgA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM6_A_29EA603_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 0.99A 4mm6A-5epgA:
undetectable		 4mm6A-5epgA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM7_A_29JA603_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 10 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.15A 4mm7A-5epgA:
undetectable		 4mm7A-5epgA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MM9_A_FVXA603_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.00A 4mm9A-5epgA:
undetectable		 4mm9A-5epgA:
17.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMB_A_SREA603_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 9 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.08A 4mmbA-5epgA:
undetectable		 4mmbA-5epgA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMC_A_29JA603_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 10 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.02A 4mmcA-5epgA:
undetectable		 4mmcA-5epgA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMD_B_29EB603_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.01A 4mmdB-5epgA:
undetectable		 4mmdB-5epgA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_A_29QA603_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 9 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.02A 4mmeA-5epgA:
undetectable		 4mmeA-5epgA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MME_B_29QB603_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 9 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.03A 4mmeB-5epgA:
undetectable		 4mmeB-5epgA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_A_29QA603_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 9 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.02A 4mmfA-5epgA:
undetectable		 4mmfA-5epgA:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MMF_B_29QB603_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 9 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.03A 4mmfB-5epgA:
1.0		 4mmfB-5epgA:
18.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4MUB_A_OAQA302_0
(SULFOTRANSFERASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 LEU A  31
VAL A  54
GLY A 146
THR A  40
MET A 352
 None
 1.07A 4mubA-5epgA:
undetectable		 4mubA-5epgA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QN9_B_DXCB610_0
(N-ACYL-PHOSPHATIDYLE
THANOLAMINE-HYDROLYZ
ING PHOSPHOLIPASE D)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		3 / 3 GLY A1232
PRO A1233
ALA A 431
 None
 0.32A 4qn9B-5epgA:
undetectable		 4qn9B-5epgA:
13.91
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		6 / 8 GLU A 577
ASP A 578
SER A1060
ARG A1061
PRO A1066
TRP A1122
 None
 1.39A 4uhxA-5epgA:
48.0		 4uhxA-5epgA:
99.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UHX_A_LZUA3008_1
(ALDEHYDE OXIDASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		7 / 8 HIS A 575
ASP A 578
SER A1060
ARG A1061
PRO A1066
TRP A1122
TRP A1125
 None
 0.92A 4uhxA-5epgA:
48.0		 4uhxA-5epgA:
99.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		6 / 8 ASP A 578
SER A1060
ARG A1061
ARG A1064
PRO A1066
TRP A1122
 None
 0.81A 4uhxA-5epgA:
48.0		 4uhxA-5epgA:
99.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		6 / 8 GLU A 577
ASP A 578
SER A1060
ARG A1061
PRO A1066
TRP A1122
 None
 1.39A 4uhxA-5epgA:
48.0		 4uhxA-5epgA:
99.93
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UHX_A_RTZA3009_1
(ALDEHYDE OXIDASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		6 / 8 HIS A 575
ASP A 578
SER A1060
ARG A1061
PRO A1066
TRP A1122
 None
 0.92A 4uhxA-5epgA:
48.0		 4uhxA-5epgA:
99.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XNX_A_41XA707_1
(TRANSPORTER)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.07A 4xnxA-5epgA:
undetectable		 4xnxA-5epgA:
17.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XP1_A_LDPA708_1
(DOPAMINE
TRANSPORTER, ISOFORM
B)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 10 ASP A1093
VAL A1163
TYR A1161
SER A1265
GLY A1192
 None
 1.12A 4xp1A-5epgA:
undetectable		 4xp1A-5epgA:
17.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZZB_D_ACTD403_0
(PROTON-GATED ION
CHANNEL)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 4 ILE A 711
ARG A 906
TYR A 873
GLU A 871
 None
 1.40A 4zzbD-5epgA:
undetectable		 4zzbD-5epgA:
13.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A6I_A_TCWA1124_1
(TRANSTHYRETIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 6 LYS A 827
ALA A 824
LEU A 610
VAL A 820
 None
 1.23A 5a6iA-5epgA:
undetectable		 5a6iA-5epgA:
6.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ALB_L_TIQL1210_1
(MEDI2452 HEAVY CHAIN
MEDI2452 LIGHT CHAIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 ILE A 968
TYR A 956
PRO A 901
ASP A 895
LEU A 892
 None
 1.25A 5albH-5epgA:
undetectable		 5albH-5epgA:
12.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 GLY A1087
GLN A1049
ARG A 921
PHE A 807
GLY A 808
 MTE  A3003 ( 3.4A)
MTE  A3003 (-4.4A)
MTE  A3003 (-3.7A)
MTE  A3003 (-3.7A)
MOS  A3005 (-4.0A)
 1.14A 5b1bA-5epgA:
2.3
5b1bB-5epgA:
undetectable
5b1bT-5epgA:
undetectable		 5b1bA-5epgA:
16.15
5b1bB-5epgA:
11.18
5b1bT-5epgA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_B_CHDB303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 GLY A1088
GLN A1049
ARG A 921
PHE A 807
GLY A 808
 MOS  A3005 ( 3.4A)
MTE  A3003 (-4.4A)
MTE  A3003 (-3.7A)
MTE  A3003 (-3.7A)
MOS  A3005 (-4.0A)
 1.17A 5b1bA-5epgA:
2.3
5b1bB-5epgA:
undetectable
5b1bT-5epgA:
undetectable		 5b1bA-5epgA:
16.15
5b1bB-5epgA:
11.18
5b1bT-5epgA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BMV_C_VLBC507_1
(TUBULIN BETA CHAIN
TUBULIN ALPHA-1B
CHAIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 6 TYR A 898
PRO A1011
TYR A1164
LEU A 973
 None
 1.29A 5bmvB-5epgA:
undetectable		 5bmvB-5epgA:
15.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BYJ_A_OQRA302_0
(SULFOTRANSFERASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 LEU A  31
VAL A  54
GLY A 146
THR A  40
MET A 352
 None
 1.06A 5byjA-5epgA:
undetectable		 5byjA-5epgA:
10.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_P_BEZP801_1
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 6 SER A  57
ALA A  85
HIS A  68
LEU A 216
 None
 1.02A 5dzkB-5epgA:
2.0
5dzkP-5epgA:
undetectable		 5dzkB-5epgA:
10.35
5dzkP-5epgA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DZK_R_BEZR801_0
(ATP-DEPENDENT CLP
PROTEASE PROTEOLYTIC
SUBUNIT 2
BEZ-LEU-LEU)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 7 SER A  57
ALA A  85
HIS A  68
LEU A 216
 None
 1.11A 5dzkD-5epgA:
2.0
5dzkR-5epgA:
undetectable		 5dzkD-5epgA:
10.35
5dzkR-5epgA:
25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5H1E_A_VDXA501_1
(VITAMIN D3 RECEPTOR)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 LEU A1262
SER A1265
ILE A1195
VAL A1099
HIS A1042
 None
 1.43A 5h1eA-5epgA:
undetectable		 5h1eA-5epgA:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_A_ADNA501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 GLU A 742
GLU A 938
THR A 937
LEU A 930
 None
 1.26A 5hm8A-5epgA:
undetectable		 5hm8A-5epgA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_B_ADNB501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 GLU A 742
GLU A 938
THR A 937
LEU A 930
 None
 1.26A 5hm8B-5epgA:
undetectable		 5hm8B-5epgA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_C_ADNC501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 GLU A 742
GLU A 938
THR A 937
LEU A 930
 None
 1.25A 5hm8C-5epgA:
undetectable		 5hm8C-5epgA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_D_ADND501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 GLU A 742
GLU A 938
THR A 937
LEU A 930
 None
 1.26A 5hm8D-5epgA:
undetectable		 5hm8D-5epgA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_E_ADNE501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 GLU A 742
GLU A 938
THR A 937
LEU A 930
 None
 1.25A 5hm8E-5epgA:
undetectable		 5hm8E-5epgA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_F_ADNF501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 GLU A 742
GLU A 938
THR A 937
LEU A 930
 None
 1.25A 5hm8F-5epgA:
undetectable		 5hm8F-5epgA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HM8_H_ADNH501_2
(ADENOSYLHOMOCYSTEINA
SE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 GLU A 742
GLU A 938
THR A 937
LEU A 930
 None
 1.26A 5hm8H-5epgA:
undetectable		 5hm8H-5epgA:
16.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HPU_A_IPHA101_0
(INSULIN, CHAIN A
INSULIN, CHAIN B)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 4 CYH A 161
LEU A 144
LEU A 140
ALA A 143
 None
 1.11A 5hpuA-5epgA:
undetectable
5hpuB-5epgA:
undetectable		 5hpuA-5epgA:
2.77
5hpuB-5epgA:
1.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HV1_A_RFPA902_1
(PHOSPHOENOLPYRUVATE
SYNTHASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 PRO A1011
ALA A1166
VAL A1188
SER A1256
ILE A 968
 None
 1.17A 5hv1A-5epgA:
undetectable		 5hv1A-5epgA:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5JNC_D_ACTD305_0
(CARBONIC ANHYDRASE 4)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 5 ALA A 336
ALA A 427
ILE A 371
LEU A 368
 None
 0.80A 5jncD-5epgA:
undetectable		 5jncD-5epgA:
11.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KB5_A_ADNA401_2
(ADENOSINE KINASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 4 ASN A 147
LEU A 144
SER A 347
LEU A 128
 None
 1.31A 5kb5A-5epgA:
undetectable		 5kb5A-5epgA:
14.29
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UUN_A_ACTA310_0
(GLUTATHIONE
S-TRANSFERASE-LIKE
PROTEIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		3 / 3 GLU A 749
HIS A 750
ARG A 848
 None
 0.92A 5uunA-5epgA:
undetectable		 5uunA-5epgA:
12.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_A_ADNA502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 4 GLU A 435
THR A 343
THR A1177
LEU A 556
 None
 1.28A 5v96A-5epgA:
undetectable		 5v96A-5epgA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_B_ADNB502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 4 GLU A 435
THR A 343
THR A1177
LEU A 556
 None
 1.29A 5v96B-5epgA:
undetectable		 5v96B-5epgA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_C_ADNC502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 4 GLU A 435
THR A 343
THR A1177
LEU A 556
 None
 1.31A 5v96C-5epgA:
undetectable		 5v96C-5epgA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V96_D_ADND502_2
(S-ADENOSYL-L-HOMOCYS
TEINE HYDROLASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 4 GLU A 435
THR A 343
THR A1177
LEU A 556
 None
 1.31A 5v96D-5epgA:
undetectable		 5v96D-5epgA:
15.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WM2_A_ACTA605_0
(SALICYLATE-AMP
LIGASE)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		3 / 3 THR A1320
THR A 517
ARG A1312
 None
 0.86A 5wm2A-5epgA:
undetectable		 5wm2A-5epgA:
17.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_B_CHDB302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 2
CYTOCHROME C OXIDASE
SUBUNIT 6A2,
MITOCHONDRIAL)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 11 GLY A1088
GLN A1049
ARG A 921
PHE A 807
GLY A 808
 MOS  A3005 ( 3.4A)
MTE  A3003 (-4.4A)
MTE  A3003 (-3.7A)
MTE  A3003 (-3.7A)
MOS  A3005 (-4.0A)
 1.25A 5x19A-5epgA:
undetectable
5x19B-5epgA:
undetectable
5x19T-5epgA:
undetectable		 5x19A-5epgA:
16.15
5x19B-5epgA:
11.18
5x19T-5epgA:
5.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X24_A_LSNA502_1
(CYTOCHROME P450 2C9)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 ALA A 107
VAL A 122
MET A 123
VAL A  89
GLY A  93
 None
 1.15A 5x24A-5epgA:
undetectable		 5x24A-5epgA:
15.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CP4_A_CAMA422_0
(CYTOCHROME P450CAM)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 8 TYR A 418
LEU A 326
VAL A 322
VAL A 297
 None
 1.04A 6cp4A-5epgA:
undetectable		 6cp4A-5epgA:
16.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6CZM_E_HISE402_0
(ATP
PHOSPHORIBOSYLTRANSF
ERASE CATALYTIC
SUBUNIT)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 9 LEU A  28
GLY A 120
THR A  88
VAL A  54
CYH A  52
 None
None
None
None
FES  A3002 (-2.1A)
 1.28A 6czmD-5epgA:
undetectable
6czmE-5epgA:
undetectable		 6czmD-5epgA:
14.88
6czmE-5epgA:
14.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_B_TA1B501_1
(TUBULIN BETA CHAIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 LEU A  31
LEU A  37
ALA A  84
LEU A  27
LEU A   7
 None
 0.99A 6ew0B-5epgA:
undetectable		 6ew0B-5epgA:
4.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_D_TA1D501_1
(TUBULIN BETA CHAIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 LEU A  31
LEU A  37
ALA A  84
LEU A  27
LEU A   7
 None
 0.98A 6ew0D-5epgA:
undetectable		 6ew0D-5epgA:
4.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_H_TA1H501_1
(TUBULIN BETA CHAIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 LEU A  31
LEU A  37
ALA A  84
LEU A  27
LEU A   7
 None
 0.98A 6ew0H-5epgA:
undetectable		 6ew0H-5epgA:
4.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EW0_I_TA1I501_1
(TUBULIN BETA CHAIN)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 LEU A  31
LEU A  37
ALA A  84
LEU A  27
LEU A   7
 None
 0.98A 6ew0I-5epgA:
undetectable		 6ew0I-5epgA:
4.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6F88_A_STRA502_1
(CYTOCHROME P450
CYP260A1)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		4 / 6 PHE A 614
LEU A 612
ALA A 677
THR A 788
 None
 0.94A 6f88A-5epgA:
undetectable		 6f88A-5epgA:
4.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNG_B_QPSB601_2
(-)		 5epg ALDEHYDE OXIDASE
(Homo
sapiens) 		5 / 12 GLY A 342
LEU A 341
GLY A 465
HIS A 358
ARG A 429
 None
None
None
FAD  A3004 (-4.0A)
FAD  A3004 (-4.1A)
 1.06A 6gngB-5epgA:
undetectable		 6gngB-5epgA:
17.83